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Template proteins with similar binding site:
Click to view | Rank | CscoreLB | PDB Hit | TM-score | RMSDa | IDENa | Cov. | BS-score | Lig. Name | Download Complex | Predicted binding site residues |
| 1 | 0.01 | 2qjyD | 0.422 | 5.10 | 0.026 | 0.640 | 0.12 | LOP | complex1.pdb.gz | 154,163,164,167,168 |
| 2 | 0.01 | 2h7v1 | 0.453 | 4.35 | 0.059 | 0.627 | 0.33 | III | complex2.pdb.gz | 170,173,177,180,181,183,184 |
| 3 | 0.01 | 1bg1A | 0.476 | 3.91 | 0.062 | 0.610 | 0.15 | QNA | complex3.pdb.gz | 168,174,175 |
| 4 | 0.01 | 2qjyP | 0.422 | 5.10 | 0.026 | 0.640 | 0.13 | LOP | complex4.pdb.gz | 176,179,186,190,191 |
| 5 | 0.01 | 2qjpJ | 0.422 | 4.90 | 0.031 | 0.623 | 0.13 | SMA | complex5.pdb.gz | 168,176,177 |
| 6 | 0.01 | 2qjkM | 0.419 | 4.97 | 0.026 | 0.627 | 0.15 | LOP | complex6.pdb.gz | 169,172,179,180,183,184 |
| 7 | 0.01 | 2qjyG | 0.420 | 5.05 | 0.026 | 0.636 | 0.28 | HEM | complex7.pdb.gz | 169,170,173,174,176,177,179 |
| 8 | 0.01 | 2qjyP | 0.422 | 5.10 | 0.026 | 0.640 | 0.12 | SMA | complex8.pdb.gz | 155,158,161,169 |
| Click on the radio buttons to visualize predicted binding site and residues. |
(a) | CscoreLB is the confidence score of predicted binding site. CscoreLB values range in between [0-1]; where a higher score indicates a more reliable ligand-binding site prediction. |
(b) | BS-score is a measure of local similarity (sequence & structure) between template binding site and predicted binding site in the query structure. Based on large scale benchmarking analysis, we have observed that a BS-score >1 reflects a significant local match between the predicted and template binding site.
| (c) | TM-score is a measure of global structural similarity between query and template protein. |
(d) | RMSDa the RMSD between residues that are structurally aligned by TM-align. |
(e) | IDENa is the percentage sequence identity in the structurally aligned region. |
(f) | Cov. represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein. |
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