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Template proteins with similar binding site:
Click to view | Rank | CscoreLB | PDB Hit | TM-score | RMSDa | IDENa | Cov. | BS-score | Lig. Name | Download Complex | Predicted binding site residues |
| 1 | 0.01 | 1sijA | 0.423 | 6.09 | 0.030 | 0.694 | 0.60 | FES | complex1.pdb.gz | 245,246,267,268,269,283,285 |
| 2 | 0.01 | 1dgjA | 0.423 | 5.87 | 0.051 | 0.683 | 0.56 | FES | complex2.pdb.gz | 218,219,220,236,246 |
| 3 | 0.01 | 3fidB | 0.419 | 4.90 | 0.017 | 0.566 | 0.51 | CXE | complex3.pdb.gz | 196,198,203,204,205,220,235,246 |
| Click on the radio buttons to visualize predicted binding site and residues. |
(a) | CscoreLB is the confidence score of predicted binding site. CscoreLB values range in between [0-1]; where a higher score indicates a more reliable ligand-binding site prediction. |
(b) | BS-score is a measure of local similarity (sequence & structure) between template binding site and predicted binding site in the query structure. Based on large scale benchmarking analysis, we have observed that a BS-score >1 reflects a significant local match between the predicted and template binding site.
| (c) | TM-score is a measure of global structural similarity between query and template protein. |
(d) | RMSDa the RMSD between residues that are structurally aligned by TM-align. |
(e) | IDENa is the percentage sequence identity in the structurally aligned region. |
(f) | Cov. represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein. |
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