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Template proteins with similar binding site:
Click to view | Rank | CscoreLB | PDB Hit | TM-score | RMSDa | IDENa | Cov. | BS-score | Lig. Name | Download Complex | Predicted binding site residues |
| 1 | 0.67 | 3f81A | 0.757 | 2.19 | 0.387 | 0.815 | 1.26 | STT | complex1.pdb.gz | 120,152,153,154,156,157,158 |
| 2 | 0.50 | 1j4xA | 0.752 | 2.28 | 0.384 | 0.815 | 1.32 | III | complex2.pdb.gz | 58,59,73,120,122,152,153,154,155,156,157,158,189,190,191,192 |
| 3 | 0.19 | 2fjmA | 0.657 | 3.14 | 0.122 | 0.810 | 0.89 | 073 | complex3.pdb.gz | 120,121,152,153,154,155,156,157,158,187,188,191 |
| Click on the radio buttons to visualize predicted binding site and residues. |
(a) | CscoreLB is the confidence score of predicted binding site. CscoreLB values range in between [0-1]; where a higher score indicates a more reliable ligand-binding site prediction. |
(b) | BS-score is a measure of local similarity (sequence & structure) between template binding site and predicted binding site in the query structure. Based on large scale benchmarking analysis, we have observed that a BS-score >1 reflects a significant local match between the predicted and template binding site.
| (c) | TM-score is a measure of global structural similarity between query and template protein. |
(d) | RMSDa the RMSD between residues that are structurally aligned by TM-align. |
(e) | IDENa is the percentage sequence identity in the structurally aligned region. |
(f) | Cov. represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein. |
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