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Template proteins with similar binding site:
Click to view | Rank | CscoreLB | PDB Hit | TM-score | RMSDa | IDENa | Cov. | BS-score | Lig. Name | Download Complex | Predicted binding site residues |
| 1 | 0.57 | 1z8gA | 0.897 | 1.63 | 0.379 | 0.944 | 1.34 | III | complex1.pdb.gz | 74,116,118,165,195,210,211,212,213,214,216,236,237,238,239,242,243,250 |
| 2 | 0.54 | 2zc9H | 0.836 | 1.24 | 0.353 | 0.866 | 1.36 | 22U | complex2.pdb.gz | 74,116,117,194,211,212,216,235,236,237,238,242,250,251 |
| 3 | 0.53 | 1ettH | 0.835 | 1.36 | 0.352 | 0.869 | 1.19 | 0ZG | complex3.pdb.gz | 74,118,210,211,216,235,236,237,238,251 |
| 4 | 0.52 | 1uvsH | 0.812 | 1.34 | 0.358 | 0.843 | 1.25 | I11 | complex4.pdb.gz | 118,194,210,211,212,213,235,236,237,238,242,243 |
| 5 | 0.50 | 5gdsH | 0.837 | 1.31 | 0.352 | 0.869 | 1.30 | III | complex5.pdb.gz | 74,212,213,216,236,237,238,239,242,243 |
| 6 | 0.38 | 1c5nH | 0.835 | 1.26 | 0.349 | 0.866 | 1.35 | ESI | complex6.pdb.gz | 210,211,216,235,237,238,239,242,243,244,250 |
| 7 | 0.37 | 1nroH | 0.835 | 1.34 | 0.348 | 0.869 | 1.02 | III | complex7.pdb.gz | 74,216,236,238,242 |
| 8 | 0.37 | 2c93B | 0.832 | 1.24 | 0.351 | 0.862 | 0.97 | C4M | complex8.pdb.gz | 74,118,213,237,238 |
| 9 | 0.36 | 1umaH | 0.838 | 1.27 | 0.348 | 0.869 | 1.11 | IN2 | complex9.pdb.gz | 74,210,211,212,213,216,242 |
| 10 | 0.36 | 1qhrB | 0.838 | 1.28 | 0.352 | 0.869 | 1.10 | 157 | complex10.pdb.gz | 74,210,211,212,213,214,215,216,235,237,238,250 |
| Click on the radio buttons to visualize predicted binding site and residues. |
(a) | CscoreLB is the confidence score of predicted binding site. CscoreLB values range in between [0-1]; where a higher score indicates a more reliable ligand-binding site prediction. |
(b) | BS-score is a measure of local similarity (sequence & structure) between template binding site and predicted binding site in the query structure. Based on large scale benchmarking analysis, we have observed that a BS-score >1 reflects a significant local match between the predicted and template binding site.
| (c) | TM-score is a measure of global structural similarity between query and template protein. |
(d) | RMSDa the RMSD between residues that are structurally aligned by TM-align. |
(e) | IDENa is the percentage sequence identity in the structurally aligned region. |
(f) | Cov. represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein. |
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