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Template proteins with similar binding site:
Click to view | Rank | CscoreLB | PDB Hit | TM-score | RMSDa | IDENa | Cov. | BS-score | Lig. Name | Download Complex | Predicted binding site residues |
| 1 | 0.01 | 2uzaB | 0.329 | 7.62 | 0.037 | 0.522 | 0.36 | SF4 | complex1.pdb.gz | 433,435,488,493,494 |
| 2 | 0.01 | 1l8aA | 0.294 | 7.66 | 0.035 | 0.470 | 0.17 | TDP | complex2.pdb.gz | 420,434,489,492,493,494 |
| 3 | 0.01 | 1u6g0 | 0.301 | 7.94 | 0.038 | 0.498 | 0.36 | III | complex3.pdb.gz | 433,487,488 |
| 4 | 0.01 | 3lplB | 0.295 | 7.69 | 0.033 | 0.471 | 0.18 | TDP | complex4.pdb.gz | 435,488,489,491 |
| 5 | 0.01 | 1b0pA | 0.318 | 8.27 | 0.045 | 0.540 | 0.36 | SF4 | complex5.pdb.gz | 431,432,444,445,446,449 |
| 6 | 0.01 | 2g25A | 0.295 | 7.73 | 0.031 | 0.475 | 0.14 | TDK | complex6.pdb.gz | 455,457,471,473 |
| 7 | 0.01 | 2g28A | 0.294 | 7.65 | 0.033 | 0.470 | 0.16 | TDK | complex7.pdb.gz | 439,457,460,478 |
| Click on the radio buttons to visualize predicted binding site and residues. |
(a) | CscoreLB is the confidence score of predicted binding site. CscoreLB values range in between [0-1]; where a higher score indicates a more reliable ligand-binding site prediction. |
(b) | BS-score is a measure of local similarity (sequence & structure) between template binding site and predicted binding site in the query structure. Based on large scale benchmarking analysis, we have observed that a BS-score >1 reflects a significant local match between the predicted and template binding site.
| (c) | TM-score is a measure of global structural similarity between query and template protein. |
(d) | RMSDa the RMSD between residues that are structurally aligned by TM-align. |
(e) | IDENa is the percentage sequence identity in the structurally aligned region. |
(f) | Cov. represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein. |
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