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Template proteins with similar binding site:
Click to view | Rank | CscoreLB | PDB Hit | TM-score | RMSDa | IDENa | Cov. | BS-score | Lig. Name | Download Complex | Predicted binding site residues |
| 1 | 0.04 | 1b9y2 | 0.826 | 1.33 | 0.177 | 0.929 | 0.22 | III | complex1.pdb.gz | 37,50,71,73,75,76,77,79,81 |
| 2 | 0.03 | 1a0rB | 0.815 | 1.53 | 0.150 | 0.941 | 0.39 | FAR | complex2.pdb.gz | 12,13,25,27,30,32,34 |
| 3 | 0.03 | 1omw0 | 0.820 | 1.49 | 0.150 | 0.941 | 0.15 | III | complex3.pdb.gz | 8,11,12,13,55,58,71 |
| 4 | 0.03 | 1tbg0 | 0.826 | 1.44 | 0.138 | 0.941 | 0.13 | III | complex4.pdb.gz | 13,14,15,16 |
| 5 | 0.03 | 1gg20 | 0.816 | 1.47 | 0.138 | 0.941 | 0.11 | III | complex5.pdb.gz | 37,73,77,78,81 |
| 6 | 0.03 | 3sfzA | 0.826 | 1.68 | 0.134 | 0.965 | 0.11 | ADP | complex6.pdb.gz | 8,20,24,25 |
| 7 | 0.01 | 1tbg8 | 0.169 | 3.71 | 0.042 | 0.282 | 0.23 | III | complex7.pdb.gz | 10,11,13,14,15,16,17,18,22,39,40 |
| 8 | 0.01 | 3ob4A | 0.336 | 4.19 | 0.049 | 0.612 | 0.12 | MLR | complex8.pdb.gz | 11,12,14,31,72,73 |
| Click on the radio buttons to visualize predicted binding site and residues. |
(a) | CscoreLB is the confidence score of predicted binding site. CscoreLB values range in between [0-1]; where a higher score indicates a more reliable ligand-binding site prediction. |
(b) | BS-score is a measure of local similarity (sequence & structure) between template binding site and predicted binding site in the query structure. Based on large scale benchmarking analysis, we have observed that a BS-score >1 reflects a significant local match between the predicted and template binding site.
| (c) | TM-score is a measure of global structural similarity between query and template protein. |
(d) | RMSDa the RMSD between residues that are structurally aligned by TM-align. |
(e) | IDENa is the percentage sequence identity in the structurally aligned region. |
(f) | Cov. represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein. |
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