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Template proteins with similar binding site:
Click to view | Rank | CscoreLB | PDB Hit | TM-score | RMSDa | IDENa | Cov. | BS-score | Lig. Name | Download Complex | Predicted binding site residues |
| 1 | 0.01 | 2h4m0 | 0.336 | 6.34 | 0.039 | 0.582 | 0.14 | III | complex1.pdb.gz | 153,177,178,179 |
| 2 | 0.01 | 2uvbA | 0.373 | 6.37 | 0.043 | 0.633 | 0.12 | NAP | complex2.pdb.gz | 150,159,196,217 |
| 3 | 0.01 | 3e1f2 | 0.357 | 6.74 | 0.046 | 0.658 | 0.31 | NA | complex3.pdb.gz | 215,216,219 |
| 4 | 0.01 | 1jz0A | 0.368 | 6.91 | 0.034 | 0.680 | 0.11 | 2FG | complex4.pdb.gz | 196,199,215 |
| 5 | 0.01 | 2ot8A | 0.314 | 6.58 | 0.038 | 0.560 | 0.14 | III | complex5.pdb.gz | 177,233,258 |
| 6 | 0.01 | 1jyyA | 0.367 | 6.62 | 0.038 | 0.665 | 0.12 | 2FL | complex6.pdb.gz | 162,221,222 |
| 7 | 0.01 | 1jyxA | 0.366 | 6.39 | 0.046 | 0.644 | 0.19 | IPT | complex7.pdb.gz | 160,194,197,199 |
| 8 | 0.01 | 1vt4I | 0.368 | 6.12 | 0.022 | 0.629 | 0.11 | DTP | complex8.pdb.gz | 231,232,233 |
| Click on the radio buttons to visualize predicted binding site and residues. |
(a) | CscoreLB is the confidence score of predicted binding site. CscoreLB values range in between [0-1]; where a higher score indicates a more reliable ligand-binding site prediction. |
(b) | BS-score is a measure of local similarity (sequence & structure) between template binding site and predicted binding site in the query structure. Based on large scale benchmarking analysis, we have observed that a BS-score >1 reflects a significant local match between the predicted and template binding site.
| (c) | TM-score is a measure of global structural similarity between query and template protein. |
(d) | RMSDa the RMSD between residues that are structurally aligned by TM-align. |
(e) | IDENa is the percentage sequence identity in the structurally aligned region. |
(f) | Cov. represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein. |
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