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Template proteins with similar binding site:
Click to view | Rank | CscoreLB | PDB Hit | TM-score | RMSDa | IDENa | Cov. | BS-score | Lig. Name | Download Complex | Predicted binding site residues |
| 1 | 0.01 | 1a9x0 | 0.363 | 8.53 | 0.038 | 0.589 | 0.19 | III | complex1.pdb.gz | 383,384,432,457,476 |
| 2 | 0.01 | 3izaA | 0.363 | 6.54 | 0.037 | 0.483 | 0.13 | ATP | complex2.pdb.gz | 395,396,433,434 |
| 3 | 0.01 | 1vt4I | 0.382 | 6.82 | 0.010 | 0.531 | 0.11 | DTP | complex3.pdb.gz | 396,434,540 |
| 4 | 0.01 | 1ce8E | 0.361 | 8.47 | 0.036 | 0.586 | 0.21 | IMP | complex4.pdb.gz | 363,432,433,455,456 |
| 5 | 0.01 | 1ce8A | 0.362 | 8.51 | 0.041 | 0.588 | 0.17 | IMP | complex5.pdb.gz | 415,433,455 |
| 6 | 0.01 | 1ce8C | 0.361 | 8.48 | 0.038 | 0.584 | 0.22 | ADP | complex6.pdb.gz | 415,433,453 |
| 7 | 0.01 | 1ce8G | 0.362 | 8.56 | 0.044 | 0.591 | 0.16 | IMP | complex7.pdb.gz | 413,433,434 |
| 8 | 0.01 | 1t36A | 0.362 | 8.48 | 0.039 | 0.586 | 0.15 | U | complex8.pdb.gz | 365,366,415,472 |
| 9 | 0.01 | 3i7nA | 0.360 | 6.65 | 0.064 | 0.486 | 0.12 | III | complex9.pdb.gz | 538,579,621 |
| 10 | 0.01 | 2zuxB | 0.392 | 5.99 | 0.069 | 0.506 | 0.25 | RAM | complex10.pdb.gz | 364,414,432 |
| Click on the radio buttons to visualize predicted binding site and residues. |
(a) | CscoreLB is the confidence score of predicted binding site. CscoreLB values range in between [0-1]; where a higher score indicates a more reliable ligand-binding site prediction. |
(b) | BS-score is a measure of local similarity (sequence & structure) between template binding site and predicted binding site in the query structure. Based on large scale benchmarking analysis, we have observed that a BS-score >1 reflects a significant local match between the predicted and template binding site.
| (c) | TM-score is a measure of global structural similarity between query and template protein. |
(d) | RMSDa the RMSD between residues that are structurally aligned by TM-align. |
(e) | IDENa is the percentage sequence identity in the structurally aligned region. |
(f) | Cov. represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein. |
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