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Template proteins with similar binding site:
Click to view | Rank | CscoreLB | PDB Hit | TM-score | RMSDa | IDENa | Cov. | BS-score | Lig. Name | Download Complex | Predicted binding site residues |
| 1 | 0.46 | 1m54C | 0.615 | 1.36 | 0.994 | 0.628 | 1.91 | HEM | complex1.pdb.gz | 50,51,52,53,54,58,62,63,64,65,226,229,230,233,262,266,314 |
| 2 | 0.46 | 1jbq0 | 0.622 | 1.10 | 0.989 | 0.632 | 1.93 | III | complex2.pdb.gz | 75,76,77,78,79,80,83,89,90,91,93,94,106,112,156,159,176,179,180,183,184,242,243,245,339,340,343,344,345,369,379,382,386,389 |
| 3 | 0.08 | 2q3dA | 0.536 | 1.58 | 0.413 | 0.553 | 1.06 | PDA | complex3.pdb.gz | 119,146,147,149,150,222,255,256,257,258,259,260,305,306,349,375,376 |
| Click on the radio buttons to visualize predicted binding site and residues. |
(a) | CscoreLB is the confidence score of predicted binding site. CscoreLB values range in between [0-1]; where a higher score indicates a more reliable ligand-binding site prediction. |
(b) | BS-score is a measure of local similarity (sequence & structure) between template binding site and predicted binding site in the query structure. Based on large scale benchmarking analysis, we have observed that a BS-score >1 reflects a significant local match between the predicted and template binding site.
| (c) | TM-score is a measure of global structural similarity between query and template protein. |
(d) | RMSDa the RMSD between residues that are structurally aligned by TM-align. |
(e) | IDENa is the percentage sequence identity in the structurally aligned region. |
(f) | Cov. represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein. |
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