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Template proteins with similar binding site:
Click to view | Rank | CscoreLB | PDB Hit | TM-score | RMSDa | IDENa | Cov. | BS-score | Lig. Name | Download Complex | Predicted binding site residues |
| 1 | 0.01 | 1zyrN | 0.337 | 6.34 | 0.020 | 0.549 | 0.59 | STD | complex1.pdb.gz | 239,242,248 |
| 2 | 0.01 | 2p9i3 | 0.132 | 5.28 | 0.036 | 0.189 | 0.63 | III | complex2.pdb.gz | 233,234,235,237,240,241,242 |
| 3 | 0.01 | 1ea0A | 0.264 | 6.86 | 0.043 | 0.463 | 0.56 | F3S | complex3.pdb.gz | 257,258,259,260,261,262,263 |
| 4 | 0.01 | 2onk2 | 0.191 | 5.94 | 0.028 | 0.294 | 0.75 | III | complex4.pdb.gz | 236,237,239,240,241,242,243,244,245,246,247,248,257 |
| Click on the radio buttons to visualize predicted binding site and residues. |
(a) | CscoreLB is the confidence score of predicted binding site. CscoreLB values range in between [0-1]; where a higher score indicates a more reliable ligand-binding site prediction. |
(b) | BS-score is a measure of local similarity (sequence & structure) between template binding site and predicted binding site in the query structure. Based on large scale benchmarking analysis, we have observed that a BS-score >1 reflects a significant local match between the predicted and template binding site.
| (c) | TM-score is a measure of global structural similarity between query and template protein. |
(d) | RMSDa the RMSD between residues that are structurally aligned by TM-align. |
(e) | IDENa is the percentage sequence identity in the structurally aligned region. |
(f) | Cov. represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein. |
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