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Template proteins with similar binding site:
Click to view | Rank | CscoreLB | PDB Hit | TM-score | RMSDa | IDENa | Cov. | BS-score | Lig. Name | Download Complex | Predicted binding site residues |
| 1 | 0.11 | 1e4xM | 0.418 | 2.73 | 0.181 | 0.475 | 0.98 | III | complex1.pdb.gz | 56,58,71,72,78,115,117,118 |
| 2 | 0.11 | 1ejoL | 0.427 | 2.41 | 0.168 | 0.479 | 1.04 | III | complex2.pdb.gz | 52,56,118,119,120,122 |
| 3 | 0.10 | 1q72H | 0.435 | 2.67 | 0.182 | 0.487 | 0.82 | COC | complex3.pdb.gz | 53,55,117,118,119 |
| 4 | 0.07 | 1cu4L | 0.427 | 2.42 | 0.143 | 0.479 | 0.84 | III | complex4.pdb.gz | 68,115,117,118 |
| 5 | 0.02 | 1indH | 0.425 | 2.63 | 0.182 | 0.479 | 0.81 | EOT | complex5.pdb.gz | 110,126,128 |
| 6 | 0.02 | 1yejL | 0.424 | 2.51 | 0.154 | 0.479 | 0.89 | PNF | complex6.pdb.gz | 61,63,110,112,113,114,124,126,128 |
| Click on the radio buttons to visualize predicted binding site and residues. |
(a) | CscoreLB is the confidence score of predicted binding site. CscoreLB values range in between [0-1]; where a higher score indicates a more reliable ligand-binding site prediction. |
(b) | BS-score is a measure of local similarity (sequence & structure) between template binding site and predicted binding site in the query structure. Based on large scale benchmarking analysis, we have observed that a BS-score >1 reflects a significant local match between the predicted and template binding site.
| (c) | TM-score is a measure of global structural similarity between query and template protein. |
(d) | RMSDa the RMSD between residues that are structurally aligned by TM-align. |
(e) | IDENa is the percentage sequence identity in the structurally aligned region. |
(f) | Cov. represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein. |
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