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Template proteins with similar binding site:
Click to view | Rank | CscoreLB | PDB Hit | TM-score | RMSDa | IDENa | Cov. | BS-score | Lig. Name | Download Complex | Predicted binding site residues |
| 1 | 0.79 | 2zckP | 0.903 | 0.45 | 1.000 | 0.908 | 1.97 | III | complex1.pdb.gz | 65,101,110,111,186,187,188,189,190,208,209,210,211,213,228,229,230,231,232,239 |
| 2 | 0.50 | 2a1dB | 0.832 | 1.44 | 0.323 | 0.866 | 1.20 | 0G6 | complex2.pdb.gz | 65,117,207,208,209,211,212,213,228,229,230,232 |
| 3 | 0.49 | 3f68H | 0.824 | 1.17 | 0.315 | 0.851 | 1.40 | 91U | complex3.pdb.gz | 65,116,208,213,227,228,229,230,231,232,241,242 |
| 4 | 0.48 | 2jh0D | 0.831 | 1.18 | 0.313 | 0.858 | 1.27 | 701 | complex4.pdb.gz | 65,107,207,208,209,210,227,229,230,232,234,241,242,243 |
| 5 | 0.48 | 1nzqH | 0.827 | 1.18 | 0.314 | 0.854 | 1.15 | 162 | complex5.pdb.gz | 65,207,208,210,213,228,229,230,234,241 |
| 6 | 0.43 | 8kme2 | 0.827 | 1.18 | 0.314 | 0.854 | 1.16 | III | complex6.pdb.gz | 117,190,210,228,229,230,234 |
| 7 | 0.34 | 1gj4H | 0.831 | 1.16 | 0.313 | 0.858 | 1.19 | 132 | complex7.pdb.gz | 50,65,66,209,210,213,227,229,230,234,235,240,241 |
| 8 | 0.34 | 1no9H | 0.834 | 1.19 | 0.311 | 0.862 | 1.20 | 4ND | complex8.pdb.gz | 65,208,209,213,227,228,229 |
| 9 | 0.33 | 1nroH | 0.835 | 1.22 | 0.310 | 0.866 | 1.05 | III | complex9.pdb.gz | 65,117,213,228,230,232 |
| 10 | 0.33 | 3qdzD | 0.829 | 1.35 | 0.307 | 0.862 | 1.08 | III | complex10.pdb.gz | 65,190,210,211,213,227,230,241 |
| Click on the radio buttons to visualize predicted binding site and residues. |
(a) | CscoreLB is the confidence score of predicted binding site. CscoreLB values range in between [0-1]; where a higher score indicates a more reliable ligand-binding site prediction. |
(b) | BS-score is a measure of local similarity (sequence & structure) between template binding site and predicted binding site in the query structure. Based on large scale benchmarking analysis, we have observed that a BS-score >1 reflects a significant local match between the predicted and template binding site.
| (c) | TM-score is a measure of global structural similarity between query and template protein. |
(d) | RMSDa the RMSD between residues that are structurally aligned by TM-align. |
(e) | IDENa is the percentage sequence identity in the structurally aligned region. |
(f) | Cov. represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein. |
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