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Template proteins with similar binding site:
Click to view | Rank | CscoreLB | PDB Hit | TM-score | RMSDa | IDENa | Cov. | BS-score | Lig. Name | Download Complex | Predicted binding site residues |
| 1 | 0.02 | 1iar0 | 0.513 | 3.60 | 0.142 | 0.722 | 0.88 | III | complex1.pdb.gz | 34,35,38,41,42,89,91,92,93,95 |
| 2 | 0.02 | 1z920 | 0.533 | 3.41 | 0.112 | 0.736 | 0.69 | III | complex2.pdb.gz | 50,57,59,78,79,82,84,113,114,115 |
| 3 | 0.02 | 1ete0 | 0.520 | 3.69 | 0.088 | 0.750 | 0.78 | III | complex3.pdb.gz | 40,41,42,82,83,84,85,86,87,90 |
| 4 | 0.01 | 1brrC | 0.504 | 4.16 | 0.054 | 0.778 | 0.78 | ARC | complex4.pdb.gz | 41,42,85 |
| 5 | 0.01 | 1nbpA | 0.515 | 4.08 | 0.069 | 0.785 | 0.63 | MHC | complex5.pdb.gz | 42,46,83 |
| 6 | 0.01 | 1bm1A | 0.502 | 4.06 | 0.036 | 0.764 | 0.70 | DPG | complex6.pdb.gz | 77,80,81,83,84,89,92 |
| Click on the radio buttons to visualize predicted binding site and residues. |
(a) | CscoreLB is the confidence score of predicted binding site. CscoreLB values range in between [0-1]; where a higher score indicates a more reliable ligand-binding site prediction. |
(b) | BS-score is a measure of local similarity (sequence & structure) between template binding site and predicted binding site in the query structure. Based on large scale benchmarking analysis, we have observed that a BS-score >1 reflects a significant local match between the predicted and template binding site.
| (c) | TM-score is a measure of global structural similarity between query and template protein. |
(d) | RMSDa the RMSD between residues that are structurally aligned by TM-align. |
(e) | IDENa is the percentage sequence identity in the structurally aligned region. |
(f) | Cov. represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein. |
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