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Template proteins with similar binding site:
Click to view | Rank | CscoreLB | PDB Hit | TM-score | RMSDa | IDENa | Cov. | BS-score | Lig. Name | Download Complex | Predicted binding site residues |
| 1 | 0.49 | 1stf1 | 0.930 | 1.26 | 0.969 | 0.990 | 1.86 | III | complex1.pdb.gz | 4,5,6,46,47,48,49,52,73,74,75,97 |
| 2 | 0.02 | 1krl0 | 0.379 | 1.88 | 0.114 | 0.439 | 1.05 | III | complex2.pdb.gz | 50,51,52,53,54,55,56,57,58,59,60,61,65,67,69,80,82,85,86,87 |
| 3 | 0.01 | 1jn5B | 0.572 | 3.65 | 0.022 | 0.857 | 0.60 | III | complex3.pdb.gz | 3,4,5,46,47,48,51 |
| Click on the radio buttons to visualize predicted binding site and residues. |
(a) | CscoreLB is the confidence score of predicted binding site. CscoreLB values range in between [0-1]; where a higher score indicates a more reliable ligand-binding site prediction. |
(b) | BS-score is a measure of local similarity (sequence & structure) between template binding site and predicted binding site in the query structure. Based on large scale benchmarking analysis, we have observed that a BS-score >1 reflects a significant local match between the predicted and template binding site.
| (c) | TM-score is a measure of global structural similarity between query and template protein. |
(d) | RMSDa the RMSD between residues that are structurally aligned by TM-align. |
(e) | IDENa is the percentage sequence identity in the structurally aligned region. |
(f) | Cov. represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein. |
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