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Template proteins with similar binding site:
Click to view | Rank | CscoreLB | PDB Hit | TM-score | RMSDa | IDENa | Cov. | BS-score | Lig. Name | Download Complex | Predicted binding site residues |
| 1 | 0.01 | 2yu91 | 0.046 | 3.92 | 0.059 | 0.056 | 0.43 | III | complex1.pdb.gz | 32,37,38,59,60,61 |
| 2 | 0.01 | 2vjt3 | 0.135 | 5.28 | 0.043 | 0.182 | 0.44 | III | complex2.pdb.gz | 31,40,58,59,60,61,63 |
| 3 | 0.01 | 1hnz4 | 0.055 | 3.92 | 0.122 | 0.065 | 0.46 | III | complex3.pdb.gz | 36,37,38,60,61,62,64 |
| 4 | 0.01 | 1l0l5 | 0.137 | 5.77 | 0.089 | 0.186 | 0.45 | III | complex4.pdb.gz | 63,64,66,74 |
| Click on the radio buttons to visualize predicted binding site and residues. |
(a) | CscoreLB is the confidence score of predicted binding site. CscoreLB values range in between [0-1]; where a higher score indicates a more reliable ligand-binding site prediction. |
(b) | BS-score is a measure of local similarity (sequence & structure) between template binding site and predicted binding site in the query structure. Based on large scale benchmarking analysis, we have observed that a BS-score >1 reflects a significant local match between the predicted and template binding site.
| (c) | TM-score is a measure of global structural similarity between query and template protein. |
(d) | RMSDa the RMSD between residues that are structurally aligned by TM-align. |
(e) | IDENa is the percentage sequence identity in the structurally aligned region. |
(f) | Cov. represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein. |
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