D-I-TASSER results for O43861-D1

Input Sequence in FASTA format

>O43861 (1147 residues)
MADQIPLYPVRSAAAAAANRKRAAYYSAAGPRPGADRHSRYQLEDESAHLDEMPLMMSEE
GFENEESDYHTLPRARIMQRKRGLEWFVCDGWKFLCTSCCGWLINICRRKKELKARTVWL
GCPEKCEEKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVISCSQFVPALKIGYLY
TYWAPLGFVLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRGKVQVKSSDIQVGDLIIV
EKNQRIPSDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSCTQQLPALGDLFSISAYV
YAQKPQMDIHSFEGTFTREDSDPPIHESLSIENTLWASTIVASGTVIGVVIYTGKETRSV
MNTSNPKNKVGLLDLELNRLTKALFLALVALSIVMVTLQGFVGPWYRNLFRFLLLFSYII
PISLRVNLDMGKAVYGWMMMKDENIPGTVVRTSTIPEELGRLVYLLTDKTGTLTQNEMIF
KRLHLGTVSYGADTMDEIQSHVRDSYSQMQSQAGGNNTGSTPLRKAQSSAPKVRKSVSSR
IHEAVKAIVLCHNVTPVYESRAGVTEETEFAEADQDFSDENRTYQASSPDEVALVQWTES
VGLTLVSRDLTSMQLKTPSGQVLSFCILQLFPFTSESKRMGVIVRDESTAEITFYMKGAD
VAMSPIVQYNDWLEEECGNMAREGLRTLVVAKKALTEEQYQDFESRYTQAKLSMHDRSLK
VAAVVESLEREMELLCLTGVEDQLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSS
HLVSRTQDIHIFRQVTSRGEAHLELNAFRRKHDCALVISGDSLEVCLKYYEHEFVELACQ
CPAVVCCRCSPTQKARIVTLLQQHTGRRTCAIGDGGNDVSMIQAADCGIGIEGKEGKQAS
LAADFSITQFRHIGRLLMVHGRNSYKRSAALGQFVMHRGLIISTMQAVFSSVFYFASVPL
YQGFLMVGYATIYTMFPVFSLVLDQDVKPEMAMLYPELYKDLTKGRSLSFKTFLIWVLIS
IYQGGILMYGALVLFESEFVHVVAISFTALILTELLMVALTVRTWHWLMVVAEFLSLGCY
VSSLAFLNEYFGIGRVSFGAFLDVAFITTVTFLWKVSAITVVSCLPLYVLKYLRRKLSPP
SYCKLAS

Predicted Secondary Structure

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340                 360                 380                 400                 420                 440                 460                 480                 500                 520                 540                 560                 580                 600                 620                 640                 660                 680                 700                 720                 740                 760                 780                 800                 820                 840                 860                 880                 900                 920                 940                 960                 980                1000                1020                1040                1060                1080                1100                1120                1140
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Sequence
MADQIPLYPVRSAAAAAANRKRAAYYSAAGPRPGADRHSRYQLEDESAHLDEMPLMMSEEGFENEESDYHTLPRARIMQRKRGLEWFVCDGWKFLCTSCCGWLINICRRKKELKARTVWLGCPEKCEEKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVISCSQFVPALKIGYLYTYWAPLGFVLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRGKVQVKSSDIQVGDLIIVEKNQRIPSDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSCTQQLPALGDLFSISAYVYAQKPQMDIHSFEGTFTREDSDPPIHESLSIENTLWASTIVASGTVIGVVIYTGKETRSVMNTSNPKNKVGLLDLELNRLTKALFLALVALSIVMVTLQGFVGPWYRNLFRFLLLFSYIIPISLRVNLDMGKAVYGWMMMKDENIPGTVVRTSTIPEELGRLVYLLTDKTGTLTQNEMIFKRLHLGTVSYGADTMDEIQSHVRDSYSQMQSQAGGNNTGSTPLRKAQSSAPKVRKSVSSRIHEAVKAIVLCHNVTPVYESRAGVTEETEFAEADQDFSDENRTYQASSPDEVALVQWTESVGLTLVSRDLTSMQLKTPSGQVLSFCILQLFPFTSESKRMGVIVRDESTAEITFYMKGADVAMSPIVQYNDWLEEECGNMAREGLRTLVVAKKALTEEQYQDFESRYTQAKLSMHDRSLKVAAVVESLEREMELLCLTGVEDQLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSSHLVSRTQDIHIFRQVTSRGEAHLELNAFRRKHDCALVISGDSLEVCLKYYEHEFVELACQCPAVVCCRCSPTQKARIVTLLQQHTGRRTCAIGDGGNDVSMIQAADCGIGIEGKEGKQASLAADFSITQFRHIGRLLMVHGRNSYKRSAALGQFVMHRGLIISTMQAVFSSVFYFASVPLYQGFLMVGYATIYTMFPVFSLVLDQDVKPEMAMLYPELYKDLTKGRSLSFKTFLIWVLISIYQGGILMYGALVLFESEFVHVVAISFTALILTELLMVALTVRTWHWLMVVAEFLSLGCYVSSLAFLNEYFGIGRVSFGAFLDVAFITTVTFLWKVSAITVVSCLPLYVLKYLRRKLSPPSYCKLAS
Prediction
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCSSSCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCSSSSSSSSCCCCCSSSSCCCCSSCCSSSSSSSCCCCCCSSSSCCCCCCCCCCSSCCCCHHHHCCCCHHHHHHCSSSSSSCCCCCCCCSSSSSSSSCCCCCCCCCCCCCCHSHSCCSSSSCCSSSSSSSSSCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCHHSHHHHHHHHHHHHHHHHCCCCCCSSCCCCHHHHHCCSSSSSCCCCCCCCCCCSSSSSSSSCCSSSCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCSSSCCCCCCHHHHHHHHHHHCCSSSSCCCCSSSSSSCCCCSSSSSSSSSSCCCCCCCCSSSSSSCCCCCSSSSSSCCCCCHHHHHHCHHHHHHHHHHHHHHHCCCSSSSSSSSCCHHHHHHHHHHHHHHHHCHHCHHHHHHHHHHHHHCCCSSSSSSSSSCCCCCCHHHHHHHHHHHCCSSSSSCCCCHHHHHHHHHHCCCCCCCCSSSSSSCCCCHHHHHHHHHHHHCCCCCSSSSCHHHHHHHHHHHHHHHHHHHHCCCCSSSSCCCHHHHHHHHHHHHHHCCCSSSSSCCCCCCHHHHHHCHHCCCCCCCCHHHHHHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHSCCCCHHHHCC
Confidence
9988888877777664445677777887778888777766666677888776787778888776655544577764211123554445553123443213565521014677898289769961456218998446766551568999999999999999999999999855424664058998877723456667899999999998997214321225763146532414578199983896514449999715898826996046887666411135345420699776753438999726887753245799981577666777531001101247742669999999322356677569999775479999999999999999988667555314555148899999999998753100114899999999998630146751313574157717614996177786444630679999998752355542011111134556654334555666630110123432244430578888877653113311233202421001233345667777514316896576999999993978651378817998368822578999996168877630589970899869999848850233310026899999999998527157999986899999999999999872121589999989999970877999999740455236999999999199999977995899999999807778997499995257658899998764202331123137899999777499999999509939998489699999999999854958999527753236777510034114651589997312012103788999999989999999999999999999999999999999846753278999999999999787889876347888999874815445431265335999999999999999999999999845874131235768999999999999974337999999999999999999999886311335514766788760389997999999999999999999866039980665169

H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340                 360                 380                 400                 420                 440                 460                 480                 500                 520                 540                 560                 580                 600                 620                 640                 660                 680                 700                 720                 740                 760                 780                 800                 820                 840                 860                 880                 900                 920                 940                 960                 980                1000                1020                1040                1060                1080                1100                1120                1140
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Sequence
MADQIPLYPVRSAAAAAANRKRAAYYSAAGPRPGADRHSRYQLEDESAHLDEMPLMMSEEGFENEESDYHTLPRARIMQRKRGLEWFVCDGWKFLCTSCCGWLINICRRKKELKARTVWLGCPEKCEEKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVISCSQFVPALKIGYLYTYWAPLGFVLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRGKVQVKSSDIQVGDLIIVEKNQRIPSDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSCTQQLPALGDLFSISAYVYAQKPQMDIHSFEGTFTREDSDPPIHESLSIENTLWASTIVASGTVIGVVIYTGKETRSVMNTSNPKNKVGLLDLELNRLTKALFLALVALSIVMVTLQGFVGPWYRNLFRFLLLFSYIIPISLRVNLDMGKAVYGWMMMKDENIPGTVVRTSTIPEELGRLVYLLTDKTGTLTQNEMIFKRLHLGTVSYGADTMDEIQSHVRDSYSQMQSQAGGNNTGSTPLRKAQSSAPKVRKSVSSRIHEAVKAIVLCHNVTPVYESRAGVTEETEFAEADQDFSDENRTYQASSPDEVALVQWTESVGLTLVSRDLTSMQLKTPSGQVLSFCILQLFPFTSESKRMGVIVRDESTAEITFYMKGADVAMSPIVQYNDWLEEECGNMAREGLRTLVVAKKALTEEQYQDFESRYTQAKLSMHDRSLKVAAVVESLEREMELLCLTGVEDQLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSSHLVSRTQDIHIFRQVTSRGEAHLELNAFRRKHDCALVISGDSLEVCLKYYEHEFVELACQCPAVVCCRCSPTQKARIVTLLQQHTGRRTCAIGDGGNDVSMIQAADCGIGIEGKEGKQASLAADFSITQFRHIGRLLMVHGRNSYKRSAALGQFVMHRGLIISTMQAVFSSVFYFASVPLYQGFLMVGYATIYTMFPVFSLVLDQDVKPEMAMLYPELYKDLTKGRSLSFKTFLIWVLISIYQGGILMYGALVLFESEFVHVVAISFTALILTELLMVALTVRTWHWLMVVAEFLSLGCYVSSLAFLNEYFGIGRVSFGAFLDVAFITTVTFLWKVSAITVVSCLPLYVLKYLRRKLSPPSYCKLAS
Prediction
6444122432244444444444443444443243444424343444444343241445554354455444334444444444434324344133113322413264445565452020203444634651260405554332220001000100110000000100100000001122100011001100000001201310322310340032111101210102030330100000103351200000000000244020102133023313113320242144044353023020102023334302301010213244444444443410010000001100000000014001001123434433320121001000000000001011000000111100100000000000000000000000000000001121340310102204112201201100022111113231100000000101021123334422434323143423234344442222222222234423420220011001111012222222211121221221122242222244423200000200240102023144420312234342230211101102241210000032474330000000123102422323220240034003300000000214045620540453154043315324430430143003300000000011413640340043034030100001223210020003003002442100002212242102210322322220011012200320054034201400340300000000151002003001412420000000001014003301001002233021001000000140310010000001100200000000000000001101121011001000002000100010000000000000001301240012104013301413100110000000001000000011000000010000000000000000001000001110111000122222222122023010000000000000000000011011000000010112110010010022042121017

Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Contact, Hydrogen and Distance Map Used in D-I-TASSER simulation

D-I-TASSER simulation is guided by the consensus contact map (left figure), distance map (middle figure) and Hydrogen bond network (right figure) derived based on confidence scores of DeepPotential. In the contact, distance map and hydrogen bond networks, the axes mark the residue index along the sequence. For the contact map, each dot represents a residue pair with predicted contact, while for the distance map and hydrogen bond network, a color scale represents a distance of 1-20+ angstroms or a angle of 0-180 degree.

Top 10 threading templates used by D-I-TASSER

Rank	PDB hit	ID1	ID2	Cov	Norm. Zscore	Download alignment		20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340                 360                 380                 400                 420                 440                 460                 480                 500                 520                 540                 560                 580                 600                 620                 640                 660                 680                 700                 720                 740                 760                 780                 800                 820                 840                 860                 880                 900                 920                 940                 960                 980                1000                1020                1040                1060                1080                1100                1120                1140                    |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |
							SS	CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCSSSCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCSSSSSSSSCCCCCSSSSCCCCSSCCSSSSSSSCCCCCCSSSSCCCCCCCCCCSSCCCCHHHHCCCCHHHHHHCSSSSSSCCCCCCCCSSSSSSSSCCCCCCCCCCCCCCHSHSCCSSSSCCSSSSSSSSSCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCHHSHHHHHHHHHHHHHHHHCCCCCCSSCCCCHHHHHCCSSSSSCCCCCCCCCCCSSSSSSSSCCSSSCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCSSSCCCCCCHHHHHHHHHHHCCSSSSCCCCSSSSSSCCCCSSSSSSSSSSCCCCCCCCSSSSSSCCCCCSSSSSSCCCCCHHHHHHCHHHHHHHHHHHHHHHCCCSSSSSSSSCCHHHHHHHHHHHHHHHHCHHCHHHHHHHHHHHHHCCCSSSSSSSSSCCCCCCHHHHHHHHHHHCCSSSSSCCCCHHHHHHHHHHCCCCCCCCSSSSSSCCCCHHHHHHHHHHHHCCCCCSSSSCHHHHHHHHHHHHHHHHHHHHCCCCSSSSCCCHHHHHHHHHHHHHHCCCSSSSSCCCCCCHHHHHHCHHCCCCCCCCHHHHHHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHSCCCCHHHHCC
							Seq	MADQIPLYPVRSAAAAAANRKRAAYYSAAGPRPGADRHSRYQLEDESAHLDEMPLMMSEEGFENEESDYHTLPRARIMQRKRGLEWFVCDGWKFLCTSCCGWLINICRRKKELKARTVWLGCPEKCEEKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVISCSQFVPALKIGYLYTYWAPLGFVLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRGKVQVKSSDIQVGDLIIVEKNQRIPSDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSCTQQLPALGDLFSISAYVYAQKPQMDIHSFEGTFTREDSDPPIHESLSIENTLWASTIVASGTVIGVVIYTGKETRSVMNTSNPKNKVGLLDLELNRLTKALFLALVALSIVMVTLQGFVGPWYRNLFRFLLLFSYIIPISLRVNLDMGKAVYGWMMMKDENIPGTVVRTSTIPEELGRLVYLLTDKTGTLTQNEMIFKRLHLGTVSYGADTMDEIQSHVRDSYSQMQSQAGGNNTGSTPLRKAQSSAPKVRKSVSSRIHEAVKAIVLCHNVTPVYESRAGVTEETEFAEADQDFSDENRTYQASSPDEVALVQWTESVGLTLVSRDLTSMQLKTPSGQVLSFCILQLFPFTSESKRMGVIVRDESTAEITFYMKGADVAMSPIVQYNDWLEEECGNMAREGLRTLVVAKKALTEEQYQDFESRYTQAKLSMHDRSLKVAAVVESLEREMELLCLTGVEDQLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSSHLVSRTQDIHIFRQVTSRGEAHLELNAFRRKHDCALVISGDSLEVCLKYYEHEFVELACQCPAVVCCRCSPTQKARIVTLLQQHTGRRTCAIGDGGNDVSMIQAADCGIGIEGKEGKQASLAADFSITQFRHIGRLLMVHGRNSYKRSAALGQFVMHRGLIISTMQAVFSSVFYFASVPLYQGFLMVGYATIYTMFPVFSLVLDQDVKPEMAMLYPELYKDLTKGRSLSFKTFLIWVLISIYQGGILMYGALVLFESEFVHVVAISFTALILTELLMVALTVRTWHWLMVVAEFLSLGCYVSSLAFLNEYFGIGRVSFGAFLDVAFITTVTFLWKVSAITVVSCLPLYVLKYLRRKLSPPSYCKLAS
1	6lcpA	0.22	0.17	5.48	1.17	DEthreader		-----------------------------------------------------------------------------------------------------------------------------YFNLPPQQFPRNKIRTAKYTFIKNLWFQFHNIANIFFLFLVILVIFPIFGGVNPGLNSVPLIVIITVTAIKDAIEDYRRTILDIELNNAPVHRLKARFHKDAWKNLVVGDFVRIYNDDELPADIIILATSDPD-GACYVETKNLD-G-ETNLKVRQ-AL-RCG-RTLKHARDCAFVIESEPQNLYKYNGAIRWKEPREMSE-PIGIDNLLLRGCHLRNTEWALGVVVFTHDTKIMMNAGITPSKRARIARELNFNVICNFGILLIMCLIAAIANGIAWTGFITFWAAVIVFQNLVPISLYISLEIVRTLQAFFIYSDVGMYPCIPKSWNISDDVGQIEYIFSDKTGTLTQNVMEFKKATINGQPYGEKAILMTFIAPDF--EDLAG----P--E----QQQATEHFMLA--LA-LCH-TVV----------AE-KQPGDP--------P-------KMIFK--AQSPDEAALVATAR-------------LGMSDGGI-------------------------VLSIIEFNSSRKRMKGADSVIYSRLTAHLEMFAVEGLRTLCIA-RREHDLAATAL-EN-----------------REEKLEEVADIEGGTAIEDRLQDGVPDTIALLADAGIKLWVLTGDKVETAINIGFSCNLLNNDMDLLRLQVNESDLEQLKTNLERFNMSPYALVIDGFTLRWVLSDLKQKFLLLCKQCKSVLCCRVSPAQKAAVVSMVKNGLDVMTLSIGDGANDVAMIQEADVGVGIAGEEGRQAVMSSDFAIGQFRFLQRLVLVHGRWSYRRLAETISNFFYKNMIWTWSIFWYQCYCNFDIAYIFEYTYILMFNLFFTSVPVILMGVLDQDSDTVSLAVPQLYRRGIERKEWTQTKFWLYMIDGVYQSVMSFFIPFIVVVSERTRLGAYIAHPAVITINGYILINTYRWDWLMLLSIVLSDVFIFFWTGVYTATTYSA------GFYQAAPQVYQELTFWMCLIVTPALCLLPRLVVKCIQFPYDVDIIRE
2	6lcpA	0.20	0.17	5.35	1.55	EigenThreader		----------------------------------APRKLYFNLPPELKDEEGHPIQQFPRNKIRTAKYTPLSFIPKNLWFQFHNIANIFFLFLVILV---------------------------IFPIFGGVNP----------------------------------------GLNSVPLIVIITVTAIKDAIEDYRRTILDIELNN------APVHRLSGKARKDAWKNLVVGDFVRIYNDDELPADIIILATSDPDGACYVETKNLDGETNLKVRQALRCGRTLKHA-------------RDCERAQFVIESAIRWKEPREMSEPIGIDNLLLRGCHLRTEWALGVVVFTGH-------DTKIMMNAGINFNVICNFGILLIMCLIAAIANGIAWGKTDASLAWFEALTGFITFWAAVIVFLYISLEIVRTLQAFFIYSDVGMYYEKISWNISDDVGQIEYIFSDKTGT-----LEFKKATINGQPYGEAYTEIAAAKVRAIRGLRELHDNPYLHDEDM-----TFIALAGKNGPEQQQATEHFMLAL--------ALCHTVVAEKQ----PGDPPKMI-FKAQSPDEAALVATARDMGFTVLGMGGINVNVM----GKDMHFPVLSIIEFNSRKRMSTIVRMPDGRILLFCKGA----DSVIYSRLRETAQHLEMFAVEGLRTLCIAERELSEEEYREWRREHDLAATALENREEKLEEVA-----DKIGTAIEDRLQ---DGVPDTIALLADAGIKLWVLTGDKVETAINIGFSCNLLNNDM-DLLRLQVNESDAEQLKTNLERFNMTGALVIDGFTLRWVLSDSLKQKFLLLCKQCKSVLCCVSPAQKAAVVSMVKNGLDVMTLSIGDGANDVAMIQEADVGVGIAVMSS-------DFAIGQFRFLQRLVLVHGRWSYRRLAETISNFFYKNMIWTWSIFWYQCYFNLFFTSVPVILMGVL---------------DQDVSDTVSLAVPQLYRRGIERKEWTKFWLYMIDGVYQSVMSFFIPFIFVVLVSERTRLGAYIAHPAVITINGYILINTYRWDWLMLLSIVLSDVFIFFWTGVYT---ATTYSAGFYQAAPQVYQELTFWMCLIVTPALCLLPRLVVKCIQKQRFPYDVDIIRE
3	7ky5A	0.27	0.24	7.27	4.71	SPARKS-K		-------------------------------------------------------------------------------------------------------------NRSDELRTVYYNLPLPPLAVYPRNKIRTTKYTPLTFFPKNILFQFHNFANIYFLILLILGAFQIFGVTNPGFASVPLIVIVIITAIKDGIEDSRRTVLDLEVNNTRTHILSGCRFAKDYWKNVKVGDIVRVHNNDEIPADMILLSTSDVDGACYVETKNLDGETNLKVRQSLKCSKIIKSSRDITRTKFWVESEGPHANLYSYQGNWQDTQNGNIRNEPVNINNLLLRGCTLRNTWAMGMVIFTGDDTKIMINAGVTPTKKSRISRELNFSVILNFVLLFILCFTAGIVNGVYYNGFVSFWVAVILYQSLVPISLYISVEIIKTAQAIFIYTDVLLYPCTPKSWNISDDLGQIEYIFSDKTGTLTQNVMEFKKCTINGVSYGRAYEKEEIAKDRETMIDELRSMSDNTQFCPSKEIVEDLKGSSGDHQQKCCEHFLLALALCHSVLVEPNKD----------------DPKKLDIKAQSPDESALVSTARQLGYSFVGSSKSGLIVEIQ-GVQKEFQVLNVLEFNSSRKRMSCIIKIPGEPKALLICKGADSVIYSRLTLLEKTALHLEEYATEGLRTLCLAQRELTWSEYERWVKTYDVAAASVTNREEELDKVTDVIERELILLGGTAIEDRLQDGVPDSIALLAEAGIKLWVLTGDKVETAINIGFSCNVLNNDMELLVVKASGPIQVVNNLVTKYLREGNFAVIIDGDALKVALNGMRRKFLLLCKNCKAVLCCRVSPAQKAAVVKLVKKTLDVMTLAIGDGSNDVAMIQSADVGVGIAGEEGRQAVMCSDYAIGQFRYVTRLVLVHGKWCYKRLAEMIPQFFYKNVIFTLSLFWYGIYNNFDGSYLFEYTYLTFYNLAFTSVPVILLAVDQDVSDTVSMLVPQLYRVGILRKEWNQTKFLWYMLDGVYQSVICFFFPYLAYHDHRYFVGVFVTAIAVTSCNFYVFMEQYRWDWFCGLFICLSLAVFYGWTGIWTS---SSSSNEFYKGAARVFAQPAYWAVLFVGVLFCLLPRFTIDCIRKIFYPKDIEIVRE
4	6lcpA	0.27	0.23	7.16	2.00	MapAlign		-----------------------------------------------------------------------------------------------------------------APRKLYFNEEGHPIQQFPRNKIRTAKYTPLSFIPKNLWFQFHNIANIFFLFLVILVIFPIFGGVNPGLNSVPLIVIITVTAIKDAIEDYRRTILDIELNN-APVHRLSARFHKDAWKNLVVGDFVRIYNDDELPADIIILATSDPDGACYVETKNLDGETNLKVRQALRCGRTLKHARDCERAQFVIESEPPQPNLYKYNGAIRWK-EPREMSEPIGIDNLLLRGCHLRNTWALGVVVFTGHDTKIMMNAGITPSKRARIARELNFNVICNFGILLIMCLIAAIANGIAWPALTGFITFWAAVQNLVPISLYISLEIVRTLQAFFIYSDVGMYYCIPKSWNISDDVGQIEYIFSDKTGTLTQNVMEFKKATINGQPYGAEEIAAAKVRAIRGLRELNPYLHDEDMTFIAPDFVEDLAGKNGPEQQQATEHFMLALALCHTVVAEKQ-----------------PGDPPKMIFKAQPDEAALVATARDMGFTVLGMSDGGINVNVM-GKDMHFPVLSIIEFNSSRKRMSTIVRMP-DGRILLFCKGADSVIYSRLKMRRETAQHLEMFAVEGLRTLCIAERELSEEEYREWRREHDLAATALENREEKLEEVADKIERDLTLLGGTAIEDRLQDGVPDTIALLADAGIKLWVLTGDKVETAINIGFSCNLLNNDMDLLRLQVNEYLQLAEEQLKTNLPSPTYALVIDGFTLRWVLSSLKQKFLLLCKQCKSVLCCRVSPAQKAAVVSMVKNGLDVMTLSIGDGANDVAMIQEADVGVGIAGEEGRQAVMSSDFAIGQFRFLQRLVLVHGRWSYRRLAETISNFFYKNMIWTWSIFWYQCYCNFDIAYI-FEYTYILMFNFFTSVPVILMGVDQDVSDTVSLAVPQLYRRGIERKEWFWLYMIDGVYQSVMSFFIPFIFVVGLDVSERTRLGAYIAHPAVITINGYILINTYRWDWLMLLSIVLSDVFIFFWTGVYTATTYSAGF---YQAAPQVYQELTFWMCLIVTPALCLLPRLVVKCIQKQRFPYDVDII--
5	6lcpA	0.25	0.23	7.00	0.79	CEthreader		----------------------------------------------------------------------------------------------------------APRKLYFNLPPELKDEEGHPIQQFPRNKIRTAKYTPLSFIPKNLWFQFHNIANIFFLFLVILVIFPIFGGVNPGLNSVPLIVIITVTAIKDAIEDYRRTILDIELNNAPVHRLSGKARHKDAWKNLVVGDFVRIYNDDELPADIIILATSDPDGACYVETKNLDGETNLKVRQALRCGRTLKHARDCERAQFVIESEPPQPNLYKYNGAIRWKEPREMSE-PIGIDNLLLRGCHLRNTWALGVVVFTGHDTKIMMNAGITPSKRARIARELNFNVICNFGILLIMCLIAAIANGIALTGFITFWAAVIVFQNLVPISLYISLEIVRTLQAFFIYSDVGMYPCIPKSWNISDDVGQIEYIFSDKTGTLTQNVMEFKKATINGQPYGEAYTEAQAGMDRRGINVEEEAKVIREEIAAAKVRAIRGLRELHDNIAPDFVEDLAGKNGPEQQQATEHFMLALALCHTVVAEKQPGDPPKMIFKAQSPDEAALVATARDMGFTVLGMSDGGINVNVMGKDMHF-PVLSIIEFNSSRKRMSTIVRM-PDGRILLFCKGADSVIYSRLDMRRETAQHLEMFAVEGLRTLCIAERELSEEEYREWRREHDLAATALENREEKLEEVADKIERDLTLLGGTAIEDRLQDGVPDTIALLADAGIKLWVLTGDKVETAINIGFSCNLLNNDMDLLRLQVNEYLQLAEEQLKTNLERPTYALVIDGFTLRWVLSSLKQKFLLLCKQCKSVLCCRVSPAQKAAVVSMVKNGLDVMTLSIGDGANDVAMIQEADVGVGIAGEEGRQAVMSSDFAIGQFRFLQRLVLVHGRWSYRRLAETISNFFYKNMIWTWSIFWYQCYCNFDIAYIFEYTYILMFNLFFTSVPVILMGVLQDVSDTVSLAVPQLYRRGIERKEWTQTKFWLYMIDGVYQSVMSFFIPFIFVVLERTRLGAYIAHPAVITINGYILINTYRWDWLMLLSIVLSDVFIFFWTGVYTATTYSAG---FYQAAPQVYQELTFWMCLIVTPALCLLPRLVVKCIQKQRFPYDVDIIRE
6	6rohA	0.30	0.26	7.82	3.78	MUSTER		------------------------------------------------------------------------------------------------------------------PRVIHINDSANSSFGYSDNHISTTKYNFATFLPKFLFQEFSKYANLFFLCTSAIQQVPHVSPTNRYTTIGTLLVVLIVSAMKECIEDIKRANSDKELNNSTAEIFSEDDFVEKRWIDIRVGDIIRVKSEEPIPADTIILSSSEPEGLCYIETANLDGETNLKIKQSRVETAKFIDVKTLKNMNGKVVSEQPNSSLYTYEGTMTLNDR----QIPLSPDQMILRGALRNTAWIFGLVIFTGHETKLLRNATATPIKRTAVEKIINRQIIALFTVLIVLILISSIGNVIMSLFFKDFLTFWILFSNLVPISLFVTVELIKYYQAFMIGSDLDLYPTVVRTSSLVEELGQIEYIFS-KTGTLTRNIMEFKSCSIAGHCYIDKIPE----------DKTATVEDGIEVGYRKFDDLKKKLNDPSDEDSPIINDFLTLLATCHTVIPEFQS------------------DGSIKYQAASPDEGALVQGGADLGYKFIIRKPNSVTVLLETGEEKEYQLLNICEFNSTRKRMSAIFRFPD-GSIKLFCKGADTVILERLDDVEATMRHLEDYASEGLRTLCLAMRDISEGEYEEWNSIYNEAATTLDNRAEKLDEAANLIEKNLILIGATAIEDKLQDGVPETIHTLQEAGIKIWVLTGDRQETAINIGMSCRLLSEDMNLLIINEETRDDTERNLLEKINALNTLALVIDGKSLGFALEELEDYLLTVAKLCKAVICCRVSPLQKALVVKMVKRKSSSLLLAIGDGANDVSMIQAAHVGVGISGMEGMQAARSADIAVGQFKFLKKLLLVHGSWSYQRISVAILYSFYKNTALYMTQFWYVFANAFSGQSIMESWTMSFYNLFFTVWPPFVIGVDQFVSSRLLERYPQLYKLGQKGQFFSVYIFWGWIINGFFHSAIVFIGTILIYLADHWSWGVTVYTTSVIIVLGKAALVTNQWTKFTLIAIPGSLLFWLIFFPIYASIFPHANISREYYVVKHTYGSGVFWLTLIVLPIFALVRDFLWKYYKRMYEPETYHVQQF
7	7ky5A	0.27	0.24	7.36	3.51	HHsearch		-------------------------------------------------------------------------------------------------------------NRSDELRTVYYNLPLLPLAVYPRNKIRTTKYTPLTFFPKNILFQFHNFANIYFLILLILGAFQIFGVTNPGFASVPLIVIVIITAIKDGIEDSRRTVLDLEVNNTRTHILSGCRFAKDYWKNVKVGDIVRVHNNDEIPADMILLSTSDVDGACYVETKNLDGETNLKVRQSLKCSKIIKSSRDITRTKFWVESEGPHANLYSYQGNFKWQDTQNIRNEPVNINNLLLRGCTLRNTKAMGMVIFTGDDTKIMINAGVTPTKKSRISRELNFSVILNFVLLFILCFTAGIVNGVYTNGFVSFWVAVILYQSLVPISLYISVEIIKTAQAIFIYTDVLLYPCTPKSWNISDDLGQIEYIFSDKTGTLTQNVMEFKKCTINGVSYGRAYTEALAGLRVEGRREKEEISMSDNTQFCPEDLTEDLKGSSGDHQQKCCEHFLLALALCHSVLVEPNKDD----------------PKKLDIKAQSPDESALVSTARQLGYSFVGSSKSGLIVEIQ-GVQKEFQVLNVLEFNSSRKRMSCIIKIPGEPKALLICKGADSVIYSRLDRLEKTALHLEEYATEGLRTLCLAQRELTWSEYERWVKTYDVAAASVTNREEELDKVTDVIERELILLGGTAIEDRLQDGVPDSIALLAEAGIKLWVLTGDKVETAINIGFSCNVLNNDMELLVVKASGEDVEEFEELKEGLPQGNFAVIIDGDALKVALNEMRRKFLLLCKNCKAVLCCRVSPAQKAAVVKLVKKT-LDVMTLIGDGSNDVAMIQSADVGVGIAGEEGRQAVMCSDYAIGQFRYVTRLVLVHGKWCYKRLAEMIPQFFYKNVIFTLSLFWYGIYNNFDGSYLFEYTYLTFYNLAFTSVPVILLVLDQDVSDTVSMLVPQLYRVGILRKEWNQTKFLWYMLDGVYQSVICFFFPYLAYHKHRYFVGVFVTAIAVTSCNFYVFMEQYRWDWFCGLFICLSLAVFYGWTGIWTSSSSS-NEFYKG--AARVFAQPAYWAVLFVGVLFCLLPRFTIDCIRKIFYPKDIEIVRE
8	7ky5A	0.26	0.23	7.22	7.48	FFAS-3D		-------------------------------------------------------------------------------------------------------------NRSDELRTVYYNLPGLPLAVYPRNKIRTTKYTPLTFFPKNILFQFHNFANIYFLILLILGAFQIFGVTNPGFASVPLIVIVIITAIKDGIEDSRRTVLDLEVNNTRTHPNPECRFAKDYWKNVKVGDIVRVHNNDEIPADMILLSTSDVDGACYVETKNLDGETNLKVRQSLKCSKIIKSSRDITRTKFWVESEGPHANLYSYQGNFKWQDTQNGNIPVNINNLLLRGCTLRNTKWAMGMVIFTGDDTKIMINAGVTPTKKSRISRELNFSVILNFVLLFILCFTAGIVNGVYYNGFVSFWVAVILYQSLVPISLYISVEIIKTAQAIFIYNAKLDYPCTPKSWNISDDLGQIEYIFSDKTGTLTQNVMEFKKCTINGVSYGRAYKEEIAKDRETMIDELRSMSDNTQFCPEDKEIVEDLKGSSGDHQQKCCEHFLLALALCHSVLV----------------EPNKDDPKKLDIKAQSPDESALVSTARQLGYSFVGSSKSGLIVEIQ-GVQKEFQVLNVLEFNSSRKRMSCIIKIPGEPKALLICKGADSVIYSRLDRLEKTALHLEEYATEGLRTLCLAQRELTWSEYERWVKTYDVAAASVTNREEELDKVTDVIERELILLGGTAIEDRLQDGVPDSIALLAEAGIKLWVLTGDKVETAINIGFSCNVLNNDMELLVVKASGGSDPIQVVNNLVTPQGNFAVIIDGDALKVALEEMRRKFLLLCKNCKAVLCCRVSPAQKAAVVKLVKKTLDVMTLAIGDGSNDVAMIQSADVGVGIAGEEGRQAVMCSDYAIGQFRYVTRLVLVHGKWCYKRLAEMIPQFFYKNVIFTLSLFWYGIYNNFDGSYLFEYTYLTFYNLAFTSVPVILLAVDQDVSDTVSMLVPQLYRVGILRKEWNQTKFLWYMLDGVYQSVICFFFPYLAYHKNRYFVGVFVTAIAVTSCNFYVFMEQYRWDWFCGLFICLSLAVFYGWTGIWT---SSSSSNEFYKGAARVFAQPAYWAVLFVGVLFCLLPRFTIDCIRKIFYPKDIEIVR-
9	6rohA	0.23	0.18	5.74	1.60	EigenThreader		-------------------------------------------------------------------------------------------------------------------PRIHINDSLANSSFGYSDNHISTTKYNLPKFLFQEFS---KYANLFFLCTSAIQQVPHVSPTNRYTTIGTLLVVLIVSAMKECIEDIKRANSDKELNNSTAEIFSEAHFVEKRWIDIRVGDIIRV-KSEEPIPADTIILSSEPEGLCYIETANLDGET-NLKIKQSR--VETAKF-------IKVVSEQPNSSLYTYEGTMTLN---DRQIPLSPD-QMILRGATLNTAWIFGLVIFTGN-------ATATPIKRTAVEKIINRQIIALFTVLIVLILISSIG------NVIMSTADLFFKDFLTFWILFVTVELIKYYQAFMIGSDLDLYYEKTDTPTSLVEELGQIEYIFSKTGT-----LEFKSCSIAGHIDKIPED----------------KTATVEDGIEV----GYRKFNDPSDE--DSPIINDFLTLLATCH--------TVIPEFQ------SDGSIK-YQAASPDEGALVQGGADLGYKFIIRKPNSVTVLLEETGEEKEYQLLNICEFNSTRKRMSAIFRFPDGSLFCKGA-----DTVILERLDEATMRHLEDYASEGLRTLCLAMRDIEEWNSIYNEAATDEAANLIEK-------------NLILIGATAIEDDG---VPETIHTLQEAGIKIWVLTGDRQETAINIGMSCRLLSEDM-NLLIINEETRDDNLLEKINALNEHQLALVIDGKSLGFA----LDYLLTVAKLCKAVICCRVSPLQKALVVKMVKRKSSSLLLAIGDGANDVSMIQAAHVGVGISGMEGMQAARSADIAVGQFKFLKKLLLVHGSWSYQRISVAILYSFYKNTALYMTQFWYVFAMESWTMSFYNLF----------FPPFVIGVFDQFVSSRLLERYPQLYKLGQKGQFFSVYIFWGWIINGFFHSAIVFIGTILIYRLADHWSWGVTVYTTSVIIVLGKAALVTNQSLLFWLIFFPIYAPHAN----------ISREYYGVVKHTYG--SGVFWLTLPIFALVRDFLWKYYKRMYEPETYHVQQFQNA
10	6rohA	0.30	0.26	7.81	5.18	CNFpred		-------------------------------------------------------------------------------------------------------------------RVIHINDSLANSFGYSDNHISTTKYNFATFLPKFLFQEFSKYANLFFLCTSAIQQVPHVSPTNRYTTIGTLLVVLIVSAMKECIEDIKRANSDKELNNSTAEIFSEDDFVEKRWIDIRVGDIIRVKSEEPIPADTIILSSSEPEGLCYIETANLDGETNLKIKQSRVETAKFIDVKTLKNMNGKVVSEQPNSSLYTYEGTMTLND----RQIPLSPDQMILRGATLRNTWIFGLVIFTGHETKLLRNATATPIKRTAVEKIINRQIIALFTVLIVLILISSIGNV-AGLFFKDFLTFWILFSNLVPISLFVTVELIKYYQAFMIGSDLDLYPTVVRTSSLVEELGQIEYIFSMKTGTLTRNIMEFKSCSIAGHCYIDKIPEDKTATVEDGIEVGY----------RKFDDLKKKLNDPSDEDSPIINDFLTLLATCHTVIPEFQS------------------DGSIKYQAASPDEGALVQGGADLGYKFIIRKPNSVTVLLEEGEEKEYQLLNICEFNSTRKRMSAIFRFP-DGSIKLFCKGADTVILERLDYVEATMRHLEDYASEGLRTLCLAMRDISEGEYEEWNSIYNEAATTLDNRAEKLDEAANLIEKNLILIGATAIEDKLQDGVPETIHTLQEAGIKIWVLTGDRQETAINIGMSCRLLSEDMNLLIINEE-TRDDTERNLLEKIN-NTLALVIDGKSLGFALEELEDYLLTVAKLCKAVICCRVSPLQKALVVKMVKRKSSSLLLAIGDGANDVSMIQAAHVGVGISGMEGMQAARSADIAVGQFKFLKKLLLVHGSWSYQRISVAILYSFYKNTALYMTQFWYVFANAFSGQSIMESWTMSFYNLFFTVWPPFVIGVFDFVSSRLLERYPQLYKLGQKGQFFSVYIFWGWIINGFFHSAIVFIGTILIY-ADHWSWGVTVYTTSVIIVLGKAALVTNQWTKFTLIAIPGSLLFWLIFFPIYASIFPHANISREYYGVVKHTGSGVFWLTLIVLPIFALVRDFLWKYYKRMYEPE-------


(a) ID1 is the number of template residues identical to query divided by number of aligned residues.
(b) ID2 is the number of template residues identical to query divided by query sequence length.
(c) Cov is equal the number of aligned template residues divided by query sequence length.
(d) Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment and is highlighted in bold.
(e) Download alignment lists the threading program used to identify the template, and provide the 3D structure of aligned regions of threading templates (threading[1-10].pdb.gz).
(f) Template residues identical to query sequence are highlighted in color.

Top 1 final models from D-I-TASSER

Rank^a	Estimated TM-score^b
1	0.6402


(a) D-I-TASSER simulations generate a large ensemble of structural conformations, i.e. decoys. These decoys are clustered by SPICKER based on pairwise structure similarity to report up to five final models from the five largest clusters. Models are ranked in descending order of cluster size. If the simulations converge well, it is possible to have less than 5 models generated, which is usually an indication of good model quality.
(b) The model confidence is quantitatified by estimated TM-score (eTM-score), calculated based on significance of threading template alignments, contact map satisfaction rate, mean absolute error between distance of model and distance of DeepPotential, and convergence of D-I-TASSER simulations. eTM-score is typically in the range of [0, 1], with higher eTM-score signifies higher model confidence.

References:
1. Wei Zheng, Chengxin Zhang, Yang Li, Robin Pearce, Eric W. Bell, Yang Zhang. Folding non-homology proteins by coupling deep-learning contact maps with I-TASSER assembly simulations. In preparation, 2020.