|
Template proteins with similar binding site:
Click to view | Rank | CscoreLB | PDB Hit | TM-score | RMSDa | IDENa | Cov. | BS-score | Lig. Name | Download Complex | Predicted binding site residues |
| 1 | 0.09 | 1h65A | 0.420 | 3.51 | 0.117 | 0.491 | 0.22 | GDP | complex1.pdb.gz | 27,28,29,40,41 |
| 2 | 0.09 | 2xtzB | 0.397 | 3.31 | 0.147 | 0.457 | 0.20 | GSP | complex2.pdb.gz | 31,39,40,41,83 |
| 3 | 0.02 | 1cjvC | 0.399 | 3.69 | 0.166 | 0.468 | 0.14 | GSP | complex3.pdb.gz | 39,40,85,126,131 |
| 4 | 0.02 | 1u0hC | 0.399 | 3.67 | 0.166 | 0.468 | 0.13 | GSP | complex4.pdb.gz | 41,44,81,82,83,135,136 |
| 5 | 0.02 | 1aztB | 0.415 | 3.57 | 0.165 | 0.486 | 0.14 | GSP | complex5.pdb.gz | 27,28,29,30,85,132 |
| 6 | 0.02 | 1azsC | 0.412 | 3.78 | 0.159 | 0.486 | 0.14 | GSP | complex6.pdb.gz | 40,82,133,134 |
| 7 | 0.01 | 1ksgA | 0.383 | 2.89 | 0.184 | 0.429 | 0.16 | GTP | complex7.pdb.gz | 37,38,39,130,131 |
| 8 | 0.01 | 3o47B | 0.398 | 3.46 | 0.164 | 0.465 | 0.24 | GDP | complex8.pdb.gz | 39,40,73,74 |
| 9 | 0.01 | 2bcjQ | 0.396 | 3.65 | 0.155 | 0.468 | 0.17 | UUU | complex9.pdb.gz | 223,275,276,278 |
| 10 | 0.01 | 2hjgA | 0.437 | 5.34 | 0.122 | 0.600 | 0.25 | GDP | complex10.pdb.gz | 40,41,42,126,128 |
| Click on the radio buttons to visualize predicted binding site and residues. |
(a) | CscoreLB is the confidence score of predicted binding site. CscoreLB values range in between [0-1]; where a higher score indicates a more reliable ligand-binding site prediction. |
(b) | BS-score is a measure of local similarity (sequence & structure) between template binding site and predicted binding site in the query structure. Based on large scale benchmarking analysis, we have observed that a BS-score >1 reflects a significant local match between the predicted and template binding site.
| (c) | TM-score is a measure of global structural similarity between query and template protein. |
(d) | RMSDa the RMSD between residues that are structurally aligned by TM-align. |
(e) | IDENa is the percentage sequence identity in the structurally aligned region. |
(f) | Cov. represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein. |
|