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I-TASSER I-TASSER-MTD C-I-TASSER QUARK C-QUARK LOMETS COACH COFACTOR MetaGO MUSTER CEthreader SEGMER FG-MD ModRefiner REMO DEMO SPRING COTH Threpp BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign CR-I-TASSER GPCR-I-TASSER MAGELLAN BindProf BindProfX SSIPe ResQ IonCom STRUM DAMpred

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GPCR-RD is a database for experimental restaints of GPCRs. Although no solved X-ray or NMR structure is available for most GPCR sequences, numerous experiments have been performed on GPCRs to identify the critical residues and motifs. Experimental restraints were systematically collected from the literature using an automated text mining algorithm combined with manual validation, with the purpose of assisting GPCR 3-D structure modeling and function annotation. The GPCR-RD data are useful for GPCR 3D structure modeling, such as the GPCR-I-TASSER algorithm. The flow chart below summarizes the procedure for the extraction of experimental data and spatial restraints from literature and other resources.

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11002 entries in GPCR-RD.
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GPCR-RD: GPCR experimental restaint database
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Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data
opsd_bovin M257V opsd_bovin M257W acm5_human S445N
acm5_human S445I acm5_human L444P adrb2_human C116R
adrb2_human C125S crfr1_mouse C128S crfr1_mouse C211S
crfr1_mouse C233S ada2a_human C201S ada2a_human V197C
ada2a_human I198C ada2a_human S199C ada2a_human S200C
ada2a_human S204C ada1b_mesau S211A ada1b_mesau S207A
ada1b_mesau C129A ada1b_mesau T130A ada1b_mesau S132A
ada1b_mesau S140A ada1b_mesau S173A ada1b_mesau S177A
ada1b_mesau Y213A ada1b_mesau C306A ada1b_mesau Y338A
adrb2_human S204S adrb2_human S207S adrb2_human S204A
adrb2_human S207A acm2_pig D103N acm2_pig D69N
bkrb1_human K118S agtr1_human A104V agtr1_human S109A
agtr1_human S115A agtr1_human W153A agtr1_human W253A
agtr1_human T260A agtr1_human M284A agtr1_human T287A
agtr1_human A291G agtr1_human A291S agtra_rat V108A
nk2r_human A52X nk2r_human W56X nk2r_human I152X
nk2r_human M252X nk2r_human T125X nk2r_human A128X
nk2r_human Y217X ghsr_human S218A ghsr_human F279H
ghsr_human H280Q ghsr_human Y284F oprm_rat H297R
oprm_rat H297N oprm_rat H297D oprm_rat H297Q
oprm_rat H297E oprm_rat H297L oprm_rat H297K
oprm_rat H297F ccr5_human Y89A agtra_rat S252A
agtra_rat V254A agtra_rat P255A agtra_rat F293A
agtra_rat N294A agtra_rat N295A agtra_rat N295T
agtra_rat N295K agtra_rat N295Q agtra_rat N295L
agtra_rat N295V ntr1_rat L66A crfr1_mouse C364S
glr_rat H178A glr_rat H178K glr_rat H178E
glr_rat T352S glr_rat T352A sctr_rat R188L
sctr_rat R188D sctr_rat R188Q sctr_rat N192A
ada1a_human S188A ada1a_human A189S ada1a_human A189T
ada1a_human S192A ada1a_human F193L ada1a_human Y194F


Reference:

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