GPCR-I-TASSER results for Q9BYT4

[Click on Q9BYT4_results.tar.bz2 to download the tarball file including all modeling results listed on this page]

  Submitted Sequence

>Q9BYT4
LCFRAKPVFLLSTANILTVIILSQLVARRQKSSYNYLLALAAADILVLFFIVFVDFLLED
FILNMQMPQVPDKIIEVLEFSSIHTSIWITVPLTIDRYIAVCHPLKYHTVSYPARTRKVI
VSVYITCFLTSIPYYWWPNIWTEDYISTSVHHVLIWIHCFTVYLVPCSIFFILNSIIVYK
LRRKSNFRLRGYSTGKTTAILFTITSIFATLWAPRIIMILYHLYGAPIQNRWLVHIMSDI
ANMLALLNTAINFFLYCFISKRFRT

  Predicted Secondary Structure

Sequence                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |     
LCFRAKPVFLLSTANILTVIILSQLVARRQKSSYNYLLALAAADILVLFFIVFVDFLLEDFILNMQMPQVPDKIIEVLEFSSIHTSIWITVPLTIDRYIAVCHPLKYHTVSYPARTRKVIVSVYITCFLTSIPYYWWPNIWTEDYISTSVHHVLIWIHCFTVYLVPCSIFFILNSIIVYKLRRKSNFRLRGYSTGKTTAILFTITSIFATLWAPRIIMILYHLYGAPIQNRWLVHIMSDIANMLALLNTAINFFLYCFISKRFRT
PredictionCCHHHHHHHHHHHHHHHHSSSSCSCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSSSSSCCCCCCCSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
Conf.Score9272574887478458466353027988777619999999999999999985299999997579658670796899999999999999999999986688672071524214889999999999999999989998726898168997202099999999999999999999999999998115676300022165999999999999999999999999999733424155999999999999999996999999980650199

  Predicted Solvent Accessibility

Sequence                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |     
LCFRAKPVFLLSTANILTVIILSQLVARRQKSSYNYLLALAAADILVLFFIVFVDFLLEDFILNMQMPQVPDKIIEVLEFSSIHTSIWITVPLTIDRYIAVCHPLKYHTVSYPARTRKVIVSVYITCFLTSIPYYWWPNIWTEDYISTSVHHVLIWIHCFTVYLVPCSIFFILNSIIVYKLRRKSNFRLRGYSTGKTTAILFTITSIFATLWAPRIIMILYHLYGAPIQNRWLVHIMSDIANMLALLNTAINFFLYCFISKRFRT
Prediction2100000012013233200100011343333212303222010220202121330000010333021010001001001300000100030021032020203002223322332000000000000000011100010023372233011100000202311331021023010100223243444444444321000000000110122323210110010014424332001001330211012000131011000244348
Values range from 0 (buried residue) to 9 (highly exposed residue)

   Predicted normalized B-factor


  Top 10 templates used by GPCR-I-TASSER

Rank PDB
Hit		Iden1Iden2Cov.Norm.
Z-score		Download
Align.		                   20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |     
Sec.Str
Seq		CCHHHHHHHHHHHHHHHHSSSSCSCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSSSSSCCCCCCCSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LCFRAKPVFLLSTANILTVIILSQLVARRQKSSYNYLLALAAADILVLFFIVFVDFLLEDFILNMQMPQVPDKIIEVLEFSSIHTSIWITVPLTIDRYIAVCHPLKYHTVSYPARTRKVIVSVYITCFLTSIPYYWWPNIWTEDYISTSVHHVLIWIHCFTVYLVPCSIFFILNSIIVYKLRRKSNFRLRGYSTGKTTAILFTITSIFATLWAPRIIMILYHLYGAPIQNRWLVHIMSDIANMLALLNTAINFFLYCFISKRFRT
14grvA 0.23 0.26 0.98 3.73Download VTAIYLALFVGTVGNSVTLFTL--ARKSLQSTVHYHLGSLALSDLLILLLAMPVELYNFIWHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVARYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAIPMLFTMGLQNRSADGTHTVKVVIQVNTFMSFLFPMLVISILNTVIANKLTVMSGSV---QALRHGVLVARAVVIAFVVCWLPYHVRRLMFCYISDEQWFDFYHYFYMLTNALAYASSAINPILYNLVSANFRQ
24n6hA 0.18 0.21 0.99 3.75Download TALYSAVCAVGLLGNVLVMFGIVRYTKMKTA-TNIYIFNLALADALATSTLPFQSAKYLME--TWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVVCMLQFPSPYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKR
34n6hA 0.20 0.21 0.98 3.24Download TALYSAVCAVGLLGNVLVMFGIVRYTKMKTA-TNIYIFNLALADALATSTLPFQSAKYLM---TWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKR
44iarA 0.18 0.27 0.96 2.63Download VMLLALITLATTLSNAFVIATVYR-TRKLHTPANYLIASLAVTDLLVSILVMPISTM-YTVTGRWTLGQVVCDFWLSSDITCCTASIWHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISISLPPFFWRQA--SECVVNTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRIADLELAARERKATKTLGIILGAFIVCWLPFFIISLVMPI-----W--FHLAIFDFFTWLGYLNSLINPIIYTMSNEDFKQ
54iarA 0.20 0.27 0.94 2.00Download LVMLLALITATTLSNAFVIATVYRTRKLHTPANY-LIASLAVTDLLVSILVMPISTMY-TVTGRWTLGQVVCDFWLSSDITCCTASIWHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISISLPPFFWRQA------SECVHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRIADGYLAARERKATKTLGIILGAFIVCWLPFFIISLVMPI----WFHL---AIFDFFTWLGYLNSLINPIIYTMSNEDFKQ
64n6hA 0.19 0.21 0.99 3.71Download TALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNI-YIFNLALADALATSTLPFQSAKYLME--TWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKR
74iarA 0.19 0.27 0.94 2.93Download LVMLLALITATTLSNAFVIATVYRTRKLH-TPANYLIASLAVTDLLVSILVMPISTMYT-VTGRWTLGQVVCDFWLSSDITCCTASIWHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISISLPPFFWRQA------SECVVILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRIADDYLAARERKATKTLGIILGAFIVCWLPFFIISLVMPI-------WFHLAIFDFFTWLGYLNSLINPIIYTMSNEDFK-
84mbsA 0.19 0.28 0.96 3.07Download PPLYSLVFIFGFVGNMLVILILINYKRLKS-MTDIYLLNLAISDLFFLLTVPFWAHYAAA---QWDFGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPNIIFHYTCSSHFPYSQWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLREK-------KRHRDVRLIFTIMIVYFLFWAPYNIVLLLNTFLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEEFRN
93pblA 0.18 0.23 0.98 3.69Download ALSYCALILAIVFGNGLVCMAVLKERALQTTT-NYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASIWNLCAISIDRYTAVVMPVHYQHGTSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRR--RKVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVS---PELYSATTWLGYVNSALNPVIYTTFNIEFRK
104n6hA 0.19 0.21 0.99 4.04Download ITALYSAVCVGLLGNVLVMFGIVRYTKMKTATNI-YIFNLALADALATSTLPFQ--SAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKG
(a)All the residues are colored in black; however, those residues in template which are identical to the residue in the query sequence are highlighted in color. Coloring scheme is based on the property of amino acids, where polar are brightly coloured while non-polar residues are colored in dark shade. (more about the colors used)
(b)Rank of templates represents the top ten threading templates used by GPCR-I-TASSER.
(c)Ident1 is the percentage sequence identity of the templates in the threading aligned region with the query sequence.
(d)Ident2 is the percentage sequence identity of the whole template chains with query sequence.
(e)Cov. represents the coverage of the threading alignment and is equal to the number of aligned residues divided by the length of query protein.
(f)Norm. Z-score is the normalized Z-score of the threading alignments. Alignment with a Normalized Z-score >1 mean a good alignment and vice versa.
(g)Download Align. provides the 3D structure of the aligned regions of the threading templates.
(h)The top 10 alignments reported above (in order of their ranking) are from the following threading programs:
       1: FFAS-3D   2: SPARKS-X   3: MUSTER   4: HHSEARCH2   5: HHSEARCH I   6: Neff-PPAS   7: HHSEARCH   8: pGenTHREADER   9: wdPPAS   10: PROSPECT2   

  Top 5 Models predicted by GPCR-I-TASSER

Generated 3D models Estimated local accuracy of models
  • Download Model 1
  • C-score=1.06 (Read more about C-score)
  • Estimated TM-score = 0.86±0.07
  • Estimated RMSD = 3.8±2.6Å

  • Download Model 2
  • C-score = 1.01

  • Download Model 3
  • C-score = -1.46

  • Download Model 4
  • C-score = 1.13




    •  Please cite following articles when you use the GPCR-I-TASSER server:
    J Zhang, J Yang, R Jang, Y Zhang. Hybrid structure modeling of G protein-coupled receptors in the human genome, submitted (2015).