Detailed GPCR-I-TASSER Statistics for Q9NZH0

Submitted Sequence

>sp|Q9NZH0|GPC5B_HUMAN
MFVASERKMRAHQVLTFLLLFVITSVASENASTSRGCGLDLLPQYVSLCDLDAIWGIVVE
AVAGAGALITLLLMLILLVRLPFIKEKEKKSPVGLHFLFLLGTLGLFGLTFAFIIQEDET
ICSVRRFLWGVLFALCFSCLLSQAWRVRRLVRHGTGPAGWQLVGLALCLMLVQVIIAVEW
LVLTVLRDTRPACAYEPMDFVMALIYDMVLLVVTLGLALFTLCGKFKRWKLNGAFLLITA
FLSVLIWVAWMTMYLFGNVKLQQGDAWNDPTLAITLAASGWVFVIFHAIPEIHCTLLPAL
QENTPNYFDTSQPRMRETAFEEDVQLPRAYMENKAFSMDEHNAALRTAGFPNGSLGKRPS
GSLGKRPSAPFRSNVYQPTEMAVVLNGGTIPTAPPSHTGRHLW

Predicted Secondary Structure

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340                 360                 380                 400
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |   
Sequence MFVASERKMRAHQVLTFLLLFVITSVASENASTSRGCGLDLLPQYVSLCDLDAIWGIVVEAVAGAGALITLLLMLILLVRLPFIKEKEKKSPVGLHFLFLLGTLGLFGLTFAFIIQEDETICSVRRFLWGVLFALCFSCLLSQAWRVRRLVRHGTGPAGWQLVGLALCLMLVQVIIAVEWLVLTVLRDTRPACAYEPMDFVMALIYDMVLLVVTLGLALFTLCGKFKRWKLNGAFLLITAFLSVLIWVAWMTMYLFGNVKLQQGDAWNDPTLAITLAASGWVFVIFHAIPEIHCTLLPALQENTPNYFDTSQPRMRETAFEEDVQLPRAYMENKAFSMDEHNAALRTAGFPNGSLGKRPSGSLGKRPSAPFRSNVYQPTEMAVVLNGGTIPTAPPSHTGRHLW
Prediction CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCSSSSCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHSSSSSSSSCCCCCCSSSCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCSSSSSSSCHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCSSCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCSSSSSCCCCCCCCCCCHHCCCCC
Conf.Score 9769888667999977108899987878898889999988896414531624159999999999999999999999987600012245445257899999999999999999854765144628899999999999999999887577440657695122005547777753531050278962675431204679678979999999999999999998743667323410999999999999999999988620133200103688899999999999999998750158999835242471444047888665643467765675400488878677643557887766676667764467888876778888986168851698779999751022469

Predicted Solvent Accessibility

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340                 360                 380                 400
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |   
Sequence MFVASERKMRAHQVLTFLLLFVITSVASENASTSRGCGLDLLPQYVSLCDLDAIWGIVVEAVAGAGALITLLLMLILLVRLPFIKEKEKKSPVGLHFLFLLGTLGLFGLTFAFIIQEDETICSVRRFLWGVLFALCFSCLLSQAWRVRRLVRHGTGPAGWQLVGLALCLMLVQVIIAVEWLVLTVLRDTRPACAYEPMDFVMALIYDMVLLVVTLGLALFTLCGKFKRWKLNGAFLLITAFLSVLIWVAWMTMYLFGNVKLQQGDAWNDPTLAITLAASGWVFVIFHAIPEIHCTLLPALQENTPNYFDTSQPRMRETAFEEDVQLPRAYMENKAFSMDEHNAALRTAGFPNGSLGKRPSGSLGKRPSAPFRSNVYQPTEMAVVLNGGTIPTAPPSHTGRHLW
Prediction 7230353304446313000300415334434630450345212410300226100000010301311220220000000201102035442100000000211331110000000112300000002110301000000000000000000113344332100000000032022000000000123413130323210000001110000220221002000341462220000000001202001200100001043323312403200000000010111010111100000002154433653245443433443354446343332424223374344435533333433644446544544444345433331101112445323643223003327

Predicted Normalized B-Factor


Read more about predicted normalized B-factor

  Top 10 Templates Used by GPCR-I-TASSER


Rank PDB
Hit		Iden1Iden2Cov.Norm.
Z-score		Download
Align.		                   20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340                 360                 380                 400
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |   
Sec.Str
Seq		CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCSSSSCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHSSSSSSSSCCCCCCSSSCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCSSSSSSSCHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCSSCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCSSSSSCCCCCCCCCCCHHCCCCC
MFVASERKMRAHQVLTFLLLFVITSVASENASTSRGCGLDLLPQYVSLCDLDAIWGIVVEAVAGAGALITLLLMLILLVRLPFIKEKEKKSPVGLHFLFLLGTLGLFGLTFAFIIQEDETICSVRRFLWGVLFALCFSCLLSQAWRVRRLVRHGTGPAGWQLVGLALCLMLVQVIIAVEWLVLTVLRDTRPACAYEPMDFVMALIYDMVLLVVTLGLALFTLCGKFKRWKLNGAFLLITAFLSVLIWVAWMTMYLFGNVKLQQGDAWNDPTLAITLAASGWVFVIFHAIPEIHCTLLPALQENTPNYFDTSQPRMRETAFEEDVQLPRAYMENKAFSMDEHNAALRTAGFPNGSLGKRPSGSLGKRPSAPFRSNVYQPTEMAVVLNGGTIPTAPPSHTGRHLW
14or2A 0.22 0.15 0.60 1.68Download ---------------------------------------------VRYLEWSNIESIIAIAFSCLGILVTLFVTLIFVLYTPVVKSSS----RELCYIILAGIFLGYVCPFTLIAKPTTTSCYLQRLLVGLSSAMCYSALVTKTNRIARILRKPRFMSAWAQVIIASILISVQLTLVVTLIIMEPPMEVYLICNTSNLGVVAPLGYNGLLIMSCTYYAFKTR--NVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSN--------YKIITTCFAVSLSVTVALGCMFTPKMYIIIAKPE-------------------------------------------------------------------------------------------------------
25l7dA 0.08 0.18 0.93 1.74Download FLRCTPDRFPEGCTNEVQNIKFNSSGQCEVPLVRTDNPKSWYEDVEGCGLFTEAEHQDMHSYIAAFGAVTGLCTLFTLATFVADWRNSNRYPAVILFYVNACFFVGSIGWLAQFMDGARREIVVIVYYALMAGFVWFVVLTYAWHTSFKALQPLSGKTSYFHLLTWSLPFVLTVAILAVAQVDGDSVSGICFVGYKNYRYRAGFVLAPIGLVLIVGGYFLIRGVMTLFSARRQLADLEDNWETLNDNLKMRAAALDAQKATPPSPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLERARSTLSKINEFFNQAEWERSFRDYVLCQANVTIGLPTKQP----------------------------IPDCEIKNRPSLLVCRLT
34or2A 0.21 0.15 0.60 2.95Download ---------------------------------------------VRYLEWSNIESIIAIAFSCLGILVTLFVTLIFVLDTPVVKSSSRE----LCYIILAGIFLGYVCPFTLIAKPTTTSCYLQRLLVGLSSAMCYSALVTKTNRIARILAKPRFMSAWAQVIIASILISVQLTLVVTLIIMEPPKEVYLICNTSNLGVVAPLGYNGLLIMSCTYYAFKT--RNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNY--------KIITTCFAVSLSVTVALGCMFTPKMYIIIAKPERN-----------------------------------------------------------------------------------------------------
46eznF 0.08 0.22 1.00 1.74Download LFAVIKFESIIHEFNWFDDRTWYPLGRVTGGTLYPGRNWLGLPIDIRNVCVLFAPLFSGVTAWATYEFTITLLMVTFMFWIKAQKTGSIMHATCAAYVFITNLIPLHVFLLILMGRYSSKLYSAYTTWYAIGTAALGVFGLIQIVAFGDFVKGQISTAKFKVIMQPVSWPAFFFDTHFLIWLFPAGVFLLFLDLKDEHVFVIAYSTPVICVSAAVALSKIFDIYLDFKIKPAALLAKLIVSGSFIFYLYLFVFHSLVDNNTWNNTHIAIVGKAMASPEEKSYEILKEHDVDYVLVIFGGLIGFGRISEGIWPEEIKERDFYTAEGEYRVDARASETYKDFPQLFNGGQATDRVRQQMITPLDVPPLDYKKDDAQGRTLRDVGELTRSSTKTRRSIKRPELGLV
54or2A 0.22 0.15 0.60 3.48Download ---------------------------------------------VRYLEWSNIESIIAIAFSCLGILVTLFVTLIFVLYTPVVKSSSR----ELCYIILAGIFLGYVCPFTLIAKPTTTSCYLQRLLVGLSSAMCYSALVTKTNRIARILRKPRFMSAWAQVIIASILISVQLTLVVTLIIMEPPMEVYLICNTSNLGVVAPLGYNGLLIMSCTYYAFKT--RNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYK--------IITTCFAVSLSVTVALGCMFTPKMYIIIAKPE-------------------------------------------------------------------------------------------------------
63orgA 0.08 0.19 0.89 1.29Download ICAIGGGLPVGWEGPNVHIACIIAHQFYRLGVFKELCTD------------RALRLQTLAAACAVGLASSFGVLYSIETIASFYLVQ------------AFWKGVLSALSGAIVYELDVRTQTLLYAILGALMGVLGALFIRCVRSIYELRMRHYPGTNRYFLVGVVALFASALQYP------FPRATINDLFKAVTIKFILVALSISFLIGAGFGRLYGELMRVVFGNAIVGSYAVVGAAAFTAGVTSCAVIIFEVTGQIRHLVPVLISVLLAVIVGNAFNTLVLMKHLPYMPILRR----------DRSPEMTAREIMHPIEGEPHLFPDSEPQHIKGILEKFPNRLPVIDANGYLLGKEIVDRLQHVVVPCDVSPI---VVTSYSLVRQLHFLFVMLMPS
74or2A 0.22 0.15 0.60 5.93Download ---------------------------------------------VRYLEWSNIESIIAIAFSCLGILVTLFVTLIFVLDTPVVKS----SSRELCYIILAGIFLGYVCPFTLIAKPTTTSCYLQRLLVGLSSAMCYSALVTKTNRIARILARKPFMSAWAQVIIASILISVQLTLVVTLIIMEPPMPVYLICNTSNLGVVAPLGYNGLLIMSCTYYAFKT--RNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNY--------KIITTCFAVSLSVTVALGCMFTPKMYIIIA-KPE------------------------------------------------------------------------------------------------------
84oo9 0.19 0.21 0.61 4.52Download -------------------------------------------SPVQYLRWGDPAPIAAVVFACLGLLATLFVTVVFYRDTPVVKSSSRE----LCYIILAGICLGYLCTF-LIAKPKQIYCYLQRIGIGLSPAMSYSALVTKTYRAARILAMSKKNSSAAQLVIAFILICIQLGIIVALFIMEPPDIVYLICNTTNLGVVAPLGYNGLLILACTFYAFKT--RNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKII--------TMCFSVSLSATVALGCMFVPKVYIILAKPERN-----------------------------------------------------------------------------------------------------
94or2A 0.22 0.15 0.60 2.41Download ---------------------------------------------VRYLEWSNIESIIAIAFSCLGILVTLFVTLIFVLYTPVVKSSS----RELCYIILAGIFLGYVCPFTLIAKPTTTSCYLQRLLVGLSSAMCYSALVTKTNRIARILRKPRFMSAWAQVIIASILISVQLTLVVTLIIMEPPKEVYLICNTSNLGVVAPLGYNGLLIMSCTYYAFKT--RNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSN--------YKIITTCFAVSLSVTVALGCMFTPKMYIIIAKPE-------------------------------------------------------------------------------------------------------
104or2 0.22 0.17 0.61 6.71Download ---------------------------------------LIPVRYL---EWSNIESIIAIAFSCLGILVTLFVTLIFVL--YRDTPVVKSSSRELCYIILAGIFLGYVCPFTLIAKPTTTSCYLQRLLVGLSSAMCYSALVTKTNRIARILAKPRFMSAWAQVIIASILISVQLTLVVTLIIMEPPMPIYLICNTSNLGVVAPLGYNGLLIMSCTYYAFKT--RNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYK--------IITTCFAVSLSVTVALGCMFTPKMYIIIAKPE-------------------------------------------------------------------------------------------------------
(a)All the residues are colored in black; however, those residues in template which are identical to the residue in the query sequence are highlighted in color. Coloring scheme is based on the property of amino acids, where polar are brightly coloured while non-polar residues are colored in dark shade. (more about the colors used)
(b)Rank of templates represents the top ten threading templates used by GPCR-I-TASSER.
(c)Ident1 is the percentage sequence identity of the templates in the threading aligned region with the query sequence.
(d)Ident2 is the percentage sequence identity of the whole template chains with query sequence.
(e)Cov. represents the coverage of the threading alignment and is equal to the number of aligned residues divided by the length of query protein.
(f)Norm. Z-score is the normalized Z-score of the threading alignments. Alignment with a Normalized Z-score >1 mean a good alignment and vice versa.
(g)Download Align. provides the 3D structure of the aligned regions of the threading templates.
(h)The top 10 alignments reported above (in order of their ranking) are from the following threading programs:
       1: MUSTER   2: PROSPECT2   3: FFAS-3D   4: PROSPECT2   5: SPARKS-X   6: pGenTHREADER   7: HHSEARCH2   8: HHSEARCH I   9: Neff-PPAS   10: HHSEARCH   

  Top 5 Models Predicted by GPCR-I-TASSER

Generated 3D models Estimated local accuracy of models
  • Download Model 1
  • C-score=-2.45 (Read more about C-score)
  • Estimated TM-score = 0.43±0.14
  • Estimated RMSD = 12.7±4.3Å

  • Download Model 2
  • C-score = -3.21

  • Download Model 3
  • C-score = -3.39

  • Download Model 4
  • C-score = -3.27

  • Download Model 5
  • C-score = -3.64


    • [Click on Q9NZH0_results.tar.bz2 to download the tarball file including all modeling results listed on this page]