Detailed GPCR-I-TASSER Statistics for Q9NYW5

Submitted Sequence

>sp|Q9NYW5|TA2R4_HUMAN
MLRLFYFSAIIASVILNFVGIIMNLFITVVNCKTWVKSHRISSSDRILFSLGITRFLMLG
LFLVNTIYFVSSNTERSVYLSAFFVLCFMFLDSSSVWFVTLLNILYCVKITNFQHSVFLL
LKRNISPKIPRLLLACVLISAFTTCLYITLSQASPFPELVTTRNNTSFNISEGILSLVVS
LVLSSSLQFIINVTSASLLIHSLRRHIQKMQKNATGFWNPQTEAHVGAMKLMVYFLILYI
PYSVATLVQYLPFYAGMDMGTKSICLIFATLYSPGHSVLIIITHPKLKTTAKKILCFKK

Predicted Secondary Structure

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   
Sequence MLRLFYFSAIIASVILNFVGIIMNLFITVVNCKTWVKSHRISSSDRILFSLGITRFLMLGLFLVNTIYFVSSNTERSVYLSAFFVLCFMFLDSSSVWFVTLLNILYCVKITNFQHSVFLLLKRNISPKIPRLLLACVLISAFTTCLYITLSQASPFPELVTTRNNTSFNISEGILSLVVSLVLSSSLQFIINVTSASLLIHSLRRHIQKMQKNATGFWNPQTEAHVGAMKLMVYFLILYIPYSVATLVQYLPFYAGMDMGTKSICLIFATLYSPGHSVLIIITHPKLKTTAKKILCFKK
Prediction CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHSSCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSSSCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCSSCCCCSSSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
Conf.Score 96589999999999999999999799999989999817878777599999999999999999982874211523010789999999999980899999999999987024078968999999987727999999999999999999998721001555021565189853378999999999999999999999999999999999999757599999998199999999999999999999999999999974366699999999999995888689997087099999999874169

Predicted Solvent Accessibility

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   
Sequence MLRLFYFSAIIASVILNFVGIIMNLFITVVNCKTWVKSHRISSSDRILFSLGITRFLMLGLFLVNTIYFVSSNTERSVYLSAFFVLCFMFLDSSSVWFVTLLNILYCVKITNFQHSVFLLLKRNISPKIPRLLLACVLISAFTTCLYITLSQASPFPELVTTRNNTSFNISEGILSLVVSLVLSSSLQFIINVTSASLLIHSLRRHIQKMQKNATGFWNPQTEAHVGAMKLMVYFLILYIPYSVATLVQYLPFYAGMDMGTKSICLIFATLYSPGHSVLIIITHPKLKTTAKKILCFKK
Prediction 63332333223213312331332122002001111034340320110000001110100111333000000022223330000000001221320010000000000000022311000001330432002101312231321111201133333333333333302232333212211333333333332133133202200220233034335334113040012001002102222332331133110123334320111112221020000001023041430130013002337

Predicted Normalized B-Factor


Read more about predicted normalized B-factor

  Top 10 Templates Used by GPCR-I-TASSER


Rank PDB
Hit		Iden1Iden2Cov.Norm.
Z-score		Download
Align.		                   20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   
Sec.Str
Seq		CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHSSCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSSSCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCSSCCCCSSSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
MLRLFYFSAIIASVILNFVGIIMNLFITVVNCKTWVKSHRISSSDRILFSLGITRFLMLGLFLVNTIYFVSSNTERSVYLSAFFVLCFMFLDSSSVWFVTLLNILYCVKITNFQHSVFLLLKRNISPKIPRLLLACVLISAFTTCLYITLSQASPFPELVTTRNNTSFNISEGILSLVVSLVLSSSLQFIINVTSASLLIHSLRRHIQKMQKNATGFWNPQTEAHVGAMKLMVYFLILYIPYSVATLVQYLPFYAGMDMGTKSICLIFATLYSPGHSVLIIITHPKLKTTAKKILCFKK
14grvA 0.13 0.18 0.93 1.17Download TDIYSKVLVTAIYLALFVVGTVGNSVTLFTLA----RKSLQSTVHYHLGSLALSDLLILLLAMPVELYNFIWVHHFGDAGCRGYYFLRDACTYATALNVASLSVARYLAIC---HPFKAK--LMSRSRTKKFISAIWLASALLAIPMLFTMGLQNRSADGTHPGGLVCTPIVDTATVKVVIQVNTFMSFLFPMLVISILNTVIANKLTVMSGSVQALR----HGVLVARAVVIAFVVCWLPYHVRRLMFCYISDEQWTHYFYMLTNALAYASSAINPILYNLVSANFRQV---------
25tjvA 0.12 0.20 0.92 2.70Download LNPSQQLAIAVLSLTLGTFTVLENLLVLCVILH--SRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLAAIDRYISIHRPLAYKRIVTRPKA----VVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPH------IDETYLMFWIGVTSVLLLFIVYAYMYILWKAGKRAMSFSD--------QARMDIRLAKTLVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMF----
34n6hA 0.09 0.15 0.94 2.13Download SSLALAIAITALYSAVCAVGLLGNVLVMFGIVRY--TKMK-TATNIYIFNLALADALATST-LPFQSAKYLMETPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKA----LDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRD----GAVVCMLQFYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSV-----RLLSGSK-EKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPC
44ib4 0.09 0.19 0.95 1.54Download EQGNKLHWAALLILMVIIPTIGGNTLVILAVSL---EKKLQYATNYFLMSLAVADLLVGLFVMPIALLTIMWPLPLVLCP--AWLFLDVLFSTASIWHLCAISVDRYIAIKKPIQANQ----YNSRATAFIKITVVWLISIGIAIPVPIKIETNPNNI-TCVLTK-----ERFGDFMLFGSLAAFFTPLAIMIVTYFLTIHALQKKAADLEDNWEQKYLQTISNEQRASKVLGIVFFLFLLMWCPFFITNITLVLCSLQMLLEIFVWIGYVSSGVNPLVYTLFNKTFRDAFGRYITCNY
55glh 0.11 0.18 0.91 1.21Download IKETFKYINTVVSCLVFVLGIIGNSTLLYIIYK--------NGPNILIASLALGDLLHIVIAIPINVYKLLEDWPFGAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVAS---W-----------WTAVEIVLIWVVSVVLAVPEAIGFDIITMDYKGSYLRICLLHPVAFMQFDWWLFSFYFCLPLAITAFFYTLMTCEMLRKNEGLRLTWDAYLNDHLKQRREVAKTVFCLVLVFALCWLPLHLARLKLTLYNNLVLDYIGINMASLNSCANPIALYLVSKRFKNAFKSAL----
64djhA 0.10 0.17 0.94 1.61Download -SPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRY---TKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKA----LDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSD-------RNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFP--
74djh 0.09 0.18 0.96 1.71Download --PAIPVIITAVYSVVFVVGLVGNSLVMFVIIR---YTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVR--EDVDVIECSLQFPDDDYSDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGNAYREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGS---AALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCF---
84buoA 0.12 0.20 0.94 2.19Download TDIYSKVLVTAIYLALFVVGTVGNSVTLFTLAR---KKSLQSTVDYYLGSLALSDLLILLLAMPVELYNFIWPWAFGDAGCRGYYFLRDACTYATALNVVSLSVELYLAICH-------PFKAKTRSRTKKFISAIWLASALLAIPMLFTMGLQNLSGDGTHPGGLVCTPITLKVVIQVNTFMSFLFPMLVASILNTVIANKLTVMVHQ-----PGRVQALRRGVLVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTHYFYMLTNALVYVSAAINPILYNLVSANFRQVFLSTL----
94djhA 0.10 0.17 0.93 1.45Download -SPAIPVIITAVYSVVFVVGLVGNSLVMFVIIR----TKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKA----LDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSD-----------RNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFP--
104ea3A 0.12 0.16 0.91 1.60Download -PLGLKVTIVGLYLAVCVGGLLGNCLVMYVILR---HTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHP-----------TSSKAQAVNVAIWALASVVGVPVAIMGSAQVEDEEIECLVEIPTPQDWGPVFAICIFLFSFIVPVLVISVCYSLMIRRLRG------VRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQVAILRFCTALGYVNSCLNPILYAFLDENFKACFR-------
(a)All the residues are colored in black; however, those residues in template which are identical to the residue in the query sequence are highlighted in color. Coloring scheme is based on the property of amino acids, where polar are brightly coloured while non-polar residues are colored in dark shade. (more about the colors used)
(b)Rank of templates represents the top ten threading templates used by GPCR-I-TASSER.
(c)Ident1 is the percentage sequence identity of the templates in the threading aligned region with the query sequence.
(d)Ident2 is the percentage sequence identity of the whole template chains with query sequence.
(e)Cov. represents the coverage of the threading alignment and is equal to the number of aligned residues divided by the length of query protein.
(f)Norm. Z-score is the normalized Z-score of the threading alignments. Alignment with a Normalized Z-score >1 mean a good alignment and vice versa.
(g)Download Align. provides the 3D structure of the aligned regions of the threading templates.
(h)The top 10 alignments reported above (in order of their ranking) are from the following threading programs:
       1: MUSTER   2: FFAS-3D   3: SPARKS-X   4: HHSEARCH2   5: HHSEARCH I   6: Neff-PPAS   7: HHSEARCH   8: pGenTHREADER   9: wdPPAS   10: cdPPAS   

  Top 5 Models Predicted by GPCR-I-TASSER

Generated 3D models Estimated local accuracy of models
  • Download Model 1
  • C-score=-0.05 (Read more about C-score)
  • Estimated TM-score = 0.71±0.12
  • Estimated RMSD = 6.3±3.8Å

  • Download Model 2
  • C-score = -2.96

  • Download Model 3
  • C-score = -2.87

  • Download Model 4
  • C-score = -3.04

  • Download Model 5
  • C-score = -4.75


    • [Click on Q9NYW5_results.tar.bz2 to download the tarball file including all modeling results listed on this page]