Detailed GPCR-I-TASSER Statistics for Q8NGY7

Submitted Sequence

>sp|Q8NGY7|O10J6_HUMAN
MRRKNLTEVTEFVFLGFSRFHKHHITLFVVFLILYTLTVAGNAIIMTIICIDRHLHTPMY
FFLSMLASSKTVYTLFIIPQMLSSFVTQTQPISLAGCTTQTFFFVTLAINNCFLLTVMGY
DHYMAICNPLRYRVITSKKVCVQLVCGAFSIGLAMAAVQVTSIFTLPFCHTVVGHFFCDI
LPVMKLSCINTTINEIINFVVRLFVILVPMGLVFISYVLIISTVLKIASAEGWKKTFATC
AFHLTVVIVHYGCASIAYLMPKSENSIEQDLLLSVT

Predicted Secondary Structure

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                
Sequence MRRKNLTEVTEFVFLGFSRFHKHHITLFVVFLILYTLTVAGNAIIMTIICIDRHLHTPMYFFLSMLASSKTVYTLFIIPQMLSSFVTQTQPISLAGCTTQTFFFVTLAINNCFLLTVMGYDHYMAICNPLRYRVITSKKVCVQLVCGAFSIGLAMAAVQVTSIFTLPFCHTVVGHFFCDILPVMKLSCINTTINEIINFVVRLFVILVPMGLVFISYVLIISTVLKIASAEGWKKTFATCAFHLTVVIVHYGCASIAYLMPKSENSIEQDLLLSVT
Prediction CCCCCCCSSSSSSSSCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCSSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSCCCCCCCSSCCHHHHHHHHHHHHHHHHHHHHHHHHHHSSSCCCCCCCCCSSCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHSSSSCCCCCCCCCCCSSSSSC
Conf.Score 999887345677776689984349999999999999999989999899972887657488998779999788883377889898656996786899999999999999999999999985511502665448850478799999999999999999999998658227899267654580888888605861999999999999999979999999999999981287736564054456878997999973242268378999988778677519

Predicted Solvent Accessibility

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                
Sequence MRRKNLTEVTEFVFLGFSRFHKHHITLFVVFLILYTLTVAGNAIIMTIICIDRHLHTPMYFFLSMLASSKTVYTLFIIPQMLSSFVTQTQPISLAGCTTQTFFFVTLAINNCFLLTVMGYDHYMAICNPLRYRVITSKKVCVQLVCGAFSIGLAMAAVQVTSIFTLPFCHTVVGHFFCDILPVMKLSCINTTINEIINFVVRLFVILVPMGLVFISYVLIISTVLKIASAEGWKKTFATCAFHLTVVIVHYGCASIAYLMPKSENSIEQDLLLSVT
Prediction 875623020000000000432501010013033313312333320020010133000000210210022032112033030002011663201030022012001000210010001001100000021120213003300000021012101310310011003020143301000002210030003203110221122123313313310330332000000103246323200000000200000112000000010326335434103207

Predicted Normalized B-Factor


Read more about predicted normalized B-factor

  Top 10 Templates Used by GPCR-I-TASSER


Rank PDB
Hit		Iden1Iden2Cov.Norm.
Z-score		Download
Align.		                   20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                
Sec.Str
Seq		CCCCCCCSSSSSSSSCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCSSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSCCCCCCCSSCCHHHHHHHHHHHHHHHHHHHHHHHHHHSSSCCCCCCCCCSSCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHSSSSCCCCCCCCCCCSSSSSC
MRRKNLTEVTEFVFLGFSRFHKHHITLFVVFLILYTLTVAGNAIIMTIICIDRHLHTPMYFFLSMLASSKTVYTLFIIPQMLSSFVTQTQPISLAGCTTQTFFFVTLAINNCFLLTVMGYDHYMAICNPLRYRVITSKKVCVQLVCGAFSIGLAMAAVQVTSIFTLPFCHTVVGHFFCDILPVMKLSCINTTINEIINFVVRLFVILVPMGLVFISYVLIISTVLKIASAEGWKKTFATCAFHLTVVIVHYGCASIAYLMPKSENSIEQDLLLSVT
13emlA 0.17 0.19 0.87 2.94Download --------------------IMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITIS---GFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGGCGGQVACLFEDVVP-----------MNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLVHAAKSLAIIVGLFALCWLPLHIINCFT-FFCPDCSHAPLWLMYLAIS
25tgzA 0.19 0.21 0.80 1.91Download -RGENFMDIECF----MVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRK-DSRNVFLFKLGGVTASFTASVGSLFLAAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVL-----------------------PLLGWNCEKLQSVDKTYLMFWIGVVSVLLLFIVYAYMYILWKAHSHAPDQARMELAKTLVLILVVLIICW-------------------------
34iaqA 0.13 0.21 0.89 2.07Download ------------YIYQDSISLPWKVLLVMLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASIWHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISISILYTVYSTVGAF-----------YFPTLLLIALYGRIYVEARSRKATKTLGIILGAFIVCWLPFFIISLVMPHLAIFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFK-------
43d4s 0.15 0.16 0.89 1.52Download ----------------------WVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIWTLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRA---THQEAINCYAEETC---CDFF-TNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLNILKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILL
54yay 0.15 0.22 0.93 1.27Download LKTTRNAYIQKYLILNSSDCNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVF-F-----IITVCAFHYE--------TLPIGLGLTKNILGFLFPFLIILTSYTLIWKALK------KNDDIFKIIMAIVLFFFFSWIPHQIFTFLQLGIRDCRIDTAMPIT
63emlA 0.17 0.19 0.87 3.18Download ---------------------MGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAIT--ISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGGCGGQVACLFEDVVP-----------MNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLVHAAKSLAIIVGLFALCWLPLHIINCF-TFFCPDCSHAPLWLMYLAIV
74iaq 0.16 0.24 0.67 1.69Download --------------------LPWKVLLVMLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASIWHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISISLPPFFW-RQAS---------ECVVN----------TDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARS--------------------------------------------------
82rh1A 0.17 0.16 0.72 2.23Download -------------------DEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQM------------HWYCD-----------FFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLNIFEMLRIDEG------------------------------------L
93emlA 0.17 0.19 0.88 4.14Download --------------------IMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITIS--TGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLNCGQSQGCGGQVACLFEDVVP-----------MNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLVHAAKSLAIIVGLFALCWLPLHIINCF-TFFCPDCSHAPLWLMYLAIV
102ydoA 0.14 0.18 0.91 5.07Download -----------------------SSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSAAAADILVGVLAIPFAIA--ISTGFCAACHGCLFIACFVLVLTASSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKGKAHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESTLQKEVHAAKSLAIIVGLFALCWLTFFCPDCSHAPLWLMYLAIV
(a)All the residues are colored in black; however, those residues in template which are identical to the residue in the query sequence are highlighted in color. Coloring scheme is based on the property of amino acids, where polar are brightly coloured while non-polar residues are colored in dark shade. (more about the colors used)
(b)Rank of templates represents the top ten threading templates used by GPCR-I-TASSER.
(c)Ident1 is the percentage sequence identity of the templates in the threading aligned region with the query sequence.
(d)Ident2 is the percentage sequence identity of the whole template chains with query sequence.
(e)Cov. represents the coverage of the threading alignment and is equal to the number of aligned residues divided by the length of query protein.
(f)Norm. Z-score is the normalized Z-score of the threading alignments. Alignment with a Normalized Z-score >1 mean a good alignment and vice versa.
(g)Download Align. provides the 3D structure of the aligned regions of the threading templates.
(h)The top 10 alignments reported above (in order of their ranking) are from the following threading programs:
       1: MUSTER   2: FFAS-3D   3: SPARKS-X   4: HHSEARCH2   5: HHSEARCH I   6: Neff-PPAS   7: HHSEARCH   8: pGenTHREADER   9: wdPPAS   10: cdPPAS   

  Top 5 Models Predicted by GPCR-I-TASSER

Generated 3D models Estimated local accuracy of models
  • Download Model 1
  • C-score=-0.52 (Read more about C-score)
  • Estimated TM-score = 0.65±0.13
  • Estimated RMSD = 7.1±4.2Å

  • Download Model 2
  • C-score = -1.58

  • Download Model 3
  • C-score = -2.57

  • Download Model 4
  • C-score = -1.71

  • Download Model 5
  • C-score = -3.47


    • [Click on Q8NGY7_results.tar.bz2 to download the tarball file including all modeling results listed on this page]