Detailed GPCR-I-TASSER Statistics for Q8NGS5

Submitted Sequence

>sp|Q8NGS5|O13C4_HUMAN
MDKINQTFVREFILLGLSGYPKLEIIFFALILVMYVVILIGNGVLIIASILDSRLHMPMY
FFLGNLSFLDICYTTSSIPSTLVSLISKKRNISFSGCAVQMFFGFAMGSTECFLLGMMAF
DRYVAICNPLRYPIIMNKVVYVLLTSVSWLSGGINSTVQTSLAMRWPFCGNNIINHFLCE
ILAVLKLACSDISVNIVTLAVSNIAFLVLPLLVIFFSYMFILYTILRTNSATGRHKAFST
CSAHLTVVIIFYGTIFFMYAKPKSQDLLGKDNLQATEGLVSMFYGVVTPMLNPIIYSLRN
KDVKAAIKYLLSRKAINQ

Predicted Secondary Structure

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                  
Sequence MDKINQTFVREFILLGLSGYPKLEIIFFALILVMYVVILIGNGVLIIASILDSRLHMPMYFFLGNLSFLDICYTTSSIPSTLVSLISKKRNISFSGCAVQMFFGFAMGSTECFLLGMMAFDRYVAICNPLRYPIIMNKVVYVLLTSVSWLSGGINSTVQTSLAMRWPFCGNNIINHFLCEILAVLKLACSDISVNIVTLAVSNIAFLVLPLLVIFFSYMFILYTILRTNSATGRHKAFSTCSAHLTVVIIFYGTIFFMYAKPKSQDLLGKDNLQATEGLVSMFYGVVTPMLNPIIYSLRNKDVKAAIKYLLSRKAINQ
Prediction CCCCCCCSSSSSSSSCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCSSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHSSCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCHHHHHHHHHHHHHHHHHSSSCCCCCCCCCCCCCCCCCSSSSSSCCCHHHCCCCHHHCCCCHHHHHHHHHHHHHCCCCC
Conf.Score 999887423567797799986189999999999999999989999899974887677488887789999877762168999998478996785899999999999999999999999986506650655458831388799999999999999999999999904488998947886038088888852476199999999999999997999999999999998328660436523216587899799998537643607898786445654436729998731711121246431463999999999985043689

Predicted Solvent Accessibility

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                  
Sequence MDKINQTFVREFILLGLSGYPKLEIIFFALILVMYVVILIGNGVLIIASILDSRLHMPMYFFLGNLSFLDICYTTSSIPSTLVSLISKKRNISFSGCAVQMFFGFAMGSTECFLLGMMAFDRYVAICNPLRYPIIMNKVVYVLLTSVSWLSGGINSTVQTSLAMRWPFCGNNIINHFLCEILAVLKLACSDISVNIVTLAVSNIAFLVLPLLVIFFSYMFILYTILRTNSATGRHKAFSTCSAHLTVVIIFYGTIFFMYAKPKSQDLLGKDNLQATEGLVSMFYGVVTPMLNPIIYSLRNKDVKAAIKYLLSRKAINQ
Prediction 874623030110000000432400110013023313313333320020010013000000110200001001010030030001011652201010021011201300210020002002000000021020000003300000001001000310300000000020034130100000310001000220330012123313331331220013013200200010323622310110000000000001200100001032432454444432200000210332033003001020420130022004434268

Predicted Normalized B-Factor


Read more about predicted normalized B-factor

  Top 10 Templates Used by GPCR-I-TASSER


Rank PDB
Hit		Iden1Iden2Cov.Norm.
Z-score		Download
Align.		                   20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                  
Sec.Str
Seq		CCCCCCCSSSSSSSSCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCSSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHSSCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCHHHHHHHHHHHHHHHHHSSSCCCCCCCCCCCCCCCCCSSSSSSCCCHHHCCCCHHHCCCCHHHHHHHHHHHHHCCCCC
MDKINQTFVREFILLGLSGYPKLEIIFFALILVMYVVILIGNGVLIIASILDSRLHMPMYFFLGNLSFLDICYTTSSIPSTLVSLISKKRNISFSGCAVQMFFGFAMGSTECFLLGMMAFDRYVAICNPLRYPIIMNKVVYVLLTSVSWLSGGINSTVQTSLAMRWPFCGNNIINHFLCEILAVLKLACSDISVNIVTLAVSNIAFLVLPLLVIFFSYMFILYTILRTNSATGRHKAFSTCSAHLTVVIIFYGTIFFMYAKPKSQDLLGKDNLQATEGLVSMFYGVVTPMLNPIIYSLRNKDVKAAIKYLLSRKAINQ
13emlA 0.17 0.21 0.87 3.56Download --------------------IMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTG--FCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGGCGEGQVACLFEDVVP-----------MNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLVHAAKSLAI-IVGLFALCWLPLHIINCFTFFCPDCSHAPLWL------MYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQ
25tgzA 0.21 0.27 0.90 2.08Download -RGENFMDIECF----MVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRK-DSRNVFLFKLGGVTASFTASVGSLFLAAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVL--------PLLGWNCEK--------LQSVCSDIFPHIDKTYLMFWIGVVSVLLLFIVYAYMYILWKAHSHAPDQARMELAKTLVLILVVLIICWGPLLAIMVYDVFGKM---NKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSM--------
35tgzA 0.21 0.27 0.87 2.17Download GRGENFMD---------IENPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRK-DSRNVFLFKLGGVTASFTASVGSLFLAAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLCEKLQSVCSDIF-PHID------------------KTYLMFWIGVVSVLLLFIVYAYMYILWKAHSHAQARMDIELAKTLVLILVVLIICWGPLLAIMVDVFGKM----NKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMF-------
44ib4 0.16 0.21 0.89 1.53Download -----------------EEQGNKLHWAALLILMVIIPTIGGNTLVILAVSLEKKLQYATNYFLMSLAVADLLVGLFVMPIALLTIMEAMWPLPLVLCPAWLFLDVLFSTASIWHLCAISVDRYIAIKKPIQANQYNSRATAFIKITVVWLISIGIAIPVPIKGIE------TNPNNITCVLTK---------ERFGDFMLFGSLAAFFTPLAIMIVTYFLTIHALQKKAADLNEQRASKVLGIVFFLFLLMWCPFFITNITLVLCDSCN-QTTLQMLLEIFVWIGYVSSGVNPLVYTLFNKTFRDAFGRYITCNYR--
54yay 0.18 0.21 0.91 1.23Download KTTRN-AYIQKYLILNSSDCNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVF-F------IITVCAFHYE--------TLPIGLGLTKNILGFLFPFLIILTSYTLIWKALK------KNDDIFKIIMAIVLFFFFSWIPHQIFTFLDLGIRDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKRYFLQLL-------
63emlA 0.18 0.21 0.87 3.78Download ---------------------MGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAIT--ISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGGCGEGQVACLFEDVVP-----------MNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLVHAAKSLAIIVGLFALCWLPLHIINCF-TFFCPDCSHAP------LWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQ
73d4s 0.19 0.23 0.61 1.72Download ------------------------VGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIWTLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYR----ATHQEAINCYAE----ETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKR-------------------------------------------------------------------------------------------
82z73A 0.19 0.23 0.92 2.45Download WY--NPSIVVHPHWREFDQVPAVYYSLGIFIGICGIIGCGGNGIVIYLFTKTKSLQTPANMFIINLAFSDFTFSLVNGPLMTISCFLKKWIFGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAASKKMSHRRAFIMIIFVWLWSVLWAIGPIFGTLEGVLCNDYISR-------------DSTTRSNILCMFILG---FFGPILIIFFCYFNIVMAQAGANAEMRLAKISIVIVSQFLLSWSPYAVVALLAQFGP------LEWVTPYAAQLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVLTCC
93emlA 0.17 0.21 0.87 4.76Download --------------------IMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITIS--TGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLNCGQSQGCGEGQVACLFEDVVP-----------MNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLVHAAKSLAII-VGLFALCWLPLHIINCFTFFCPDCSHAPLWL------MYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQ
102ydoA 0.17 0.18 0.90 5.72Download -----------------------SSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSAAAADILVGVLAIPFAIA--ISTGFCAACHGCLFIACFVLVLTASSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKAHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESTLQKEVHAAKSLAIIVGLFALCWLPFFCPDCSHAPLWL------MYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQ
(a)All the residues are colored in black; however, those residues in template which are identical to the residue in the query sequence are highlighted in color. Coloring scheme is based on the property of amino acids, where polar are brightly coloured while non-polar residues are colored in dark shade. (more about the colors used)
(b)Rank of templates represents the top ten threading templates used by GPCR-I-TASSER.
(c)Ident1 is the percentage sequence identity of the templates in the threading aligned region with the query sequence.
(d)Ident2 is the percentage sequence identity of the whole template chains with query sequence.
(e)Cov. represents the coverage of the threading alignment and is equal to the number of aligned residues divided by the length of query protein.
(f)Norm. Z-score is the normalized Z-score of the threading alignments. Alignment with a Normalized Z-score >1 mean a good alignment and vice versa.
(g)Download Align. provides the 3D structure of the aligned regions of the threading templates.
(h)The top 10 alignments reported above (in order of their ranking) are from the following threading programs:
       1: MUSTER   2: FFAS-3D   3: SPARKS-X   4: HHSEARCH2   5: HHSEARCH I   6: Neff-PPAS   7: HHSEARCH   8: pGenTHREADER   9: wdPPAS   10: cdPPAS   

  Top 5 Models Predicted by GPCR-I-TASSER

Generated 3D models Estimated local accuracy of models
  • Download Model 1
  • C-score=0.02 (Read more about C-score)
  • Estimated TM-score = 0.72±0.11
  • Estimated RMSD = 6.3±3.8Å

  • Download Model 2
  • C-score = -2.30

  • Download Model 3
  • C-score = -1.34

  • Download Model 4
  • C-score = -0.71

  • Download Model 5
  • C-score = -3.09


    • [Click on Q8NGS5_results.tar.bz2 to download the tarball file including all modeling results listed on this page]