Detailed GPCR-I-TASSER Statistics for Q8NGN8

Submitted Sequence

>sp|Q8NGN8|OR4A4_HUMAN
MEPRKNVTDFVLLGFTQNPKEQKVLFVMFLLFYILTMVGNLLIVVTVTVSETLGSPMSFF
LAGLTFIDIIYSSSISPRLISDLFFGNNSISFQSFMAQLFIEHLFGGSEVFLLLVMAYDR
YVAICKPLHYLVIMRQWVCVLLLVVSWVGGFLQSVFQLSIIYGLPFCGPNVIDHFFCDMY
PLLKLACTDTHVIGLLVVANGGLSCTIAFLLLLISYGVILHSLKKLSQKGRQKAHSTCSS
HITVVVFFFVPCIFMCARPARTFSIDKSVSVFYTVITPMLNPLIYTLRNSEMTSAMKKL

Predicted Secondary Structure

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   
Sequence MEPRKNVTDFVLLGFTQNPKEQKVLFVMFLLFYILTMVGNLLIVVTVTVSETLGSPMSFFLAGLTFIDIIYSSSISPRLISDLFFGNNSISFQSFMAQLFIEHLFGGSEVFLLLVMAYDRYVAICKPLHYLVIMRQWVCVLLLVVSWVGGFLQSVFQLSIIYGLPFCGPNVIDHFFCDMYPLLKLACTDTHVIGLLVVANGGLSCTIAFLLLLISYGVILHSLKKLSQKGRQKAHSTCSSHITVVVFFFVPCIFMCARPARTFSIDKSVSVFYTVITPMLNPLIYTLRNSEMTSAMKKL
Prediction CCCCCCSSSSSSSCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHSSSSSCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCSSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHSSCCCCCCCCCCCSSCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCHHHHHHHHHHHHHHHHHHCCSSSSSCCCCCCCCCCHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHCC
Conf.Score 99997210568806999812589999999999999998788745523207999997999987499875533234719999987439967838999999999999999999999999965178746210262126775999999999998999999999992458998988367764383888889402405322004446449999999999999999999998856421209999998799933256206435884889999750000677763364010374335629999998529

Predicted Solvent Accessibility

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   
Sequence MEPRKNVTDFVLLGFTQNPKEQKVLFVMFLLFYILTMVGNLLIVVTVTVSETLGSPMSFFLAGLTFIDIIYSSSISPRLISDLFFGNNSISFQSFMAQLFIEHLFGGSEVFLLLVMAYDRYVAICKPLHYLVIMRQWVCVLLLVVSWVGGFLQSVFQLSIIYGLPFCGPNVIDHFFCDMYPLLKLACTDTHVIGLLVVANGGLSCTIAFLLLLISYGVILHSLKKLSQKGRQKAHSTCSSHITVVVFFFVPCIFMCARPARTFSIDKSVSVFYTVITPMLNPLIYTLRNSEMTSAMKKL
Prediction 87442200000000004245001000131333233233323300000200430400001002300120011000000200000036321000500000001103311310200020030000000221101000233100000120131023013001310230300010220001002210030000202300030023013202310331331121002001321461222011003002100202321010000003332330001003102310331230000205402301455

Predicted Normalized B-Factor


Read more about predicted normalized B-factor

  Top 10 Templates Used by GPCR-I-TASSER


Rank PDB
Hit		Iden1Iden2Cov.Norm.
Z-score		Download
Align.		                   20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   
Sec.Str
Seq		CCCCCCSSSSSSSCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHSSSSSCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCSSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHSSCCCCCCCCCCCSSCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCHHHHHHHHHHHHHHHHHHCCSSSSSCCCCCCCCCCHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHCC
MEPRKNVTDFVLLGFTQNPKEQKVLFVMFLLFYILTMVGNLLIVVTVTVSETLGSPMSFFLAGLTFIDIIYSSSISPRLISDLFFGNNSISFQSFMAQLFIEHLFGGSEVFLLLVMAYDRYVAICKPLHYLVIMRQWVCVLLLVVSWVGGFLQSVFQLSIIYGLPFCGPNVIDHFFCDMYPLLKLACTDTHVIGLLVVANGGLSCTIAFLLLLISYGVILHSLKKLSQKGRQKAHSTCSSHITVVVFFFVPCIFMCARPARTFSIDKSVSVFYTVITPMLNPLIYTLRNSEMTSAMKKL
15tgzA 0.20 0.24 0.93 3.35Download GENFMDIECFMVL----NPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCPSYHFIGSLAVADLLGSVIFVYSFIDFHVFH-RKDSRNVFLFKLGGVTASFTASVGSLFLAAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLG-------NCEKLQSVCSDIFPH----------IDKTYLMFWIGVVSVLLLFIVYAYMYILWKAHSHAARMDIELAKTLVLILVVLIICWGPLLAIMVYDVFGIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSM
25tgzA 0.21 0.24 0.92 2.26Download -ENFMDIECF----MVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKD-SRNVFLFKLGGVTASFTASVGSLFLAAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVL--------PLLGWNCEK---------LQSVCSDIFHIDKTYLMFWIGVVSVLLLFIVYAYMYILWKAHSHAPDQARELAKTLVLILVVLIICWGPLLAIMVKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSM
35tgzA 0.18 0.24 0.93 2.21Download -GGRGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCPSYHFIGSLAVADLLGSVIFVYSFIDFH-VFHRKDSRNVFLFKLGGVTASFTASVGSLFLAAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLCEKLQSVCSDIFPHID-------------------KTYLMFWIGVVSVLLLFIVYAYMYILWKAHSHAPRMDIELAKTLVLILVVLIICWGPLLAIMVGKMNLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSM
44djh 0.13 0.21 0.92 1.55Download -----------------SPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTT-TMPFQSTVYLMNSWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVR---EDVDVIECSLQFPDD---DYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSLSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDF
54yay 0.16 0.22 0.93 1.22Download KTRNAYIQKYLILNSSDCNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFF-------IITVCAFHYE--------TLPIGLGLTKNILGFLFPFLIILTSYTLIWKALK-----KNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVGRVDTAMPITICIAYFNNCLNPLFYGFLGKKFKRYFLQL
65tgzA 0.21 0.24 0.93 3.70Download -ENFMDIECFMVLN----PSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRK-DSRNVFLFKLGGVTASFTASVGSLFLAAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAV--------LPLLGWNCEK--------LQSVCSDIFPHIDKTYLMFWIGVVSVLLLFIVYAYMYILWKAHSHAPDQAIELAKTLVLILVVLIICWGPLLAIMVYDVFGIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSM
74iaq 0.20 0.25 0.62 1.72Download -------------------PWKVLLVMLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASIWHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISISLPPFF-WRQASE----------CVVNT-------D---HILYTVYSTVGAFYFPTLLLIALYGRIYVEARSR-------------------------------------------------------------------------
84buoA 0.15 0.19 0.91 2.70Download ---NSD------LDVNTDIYSKVLVTAIYLALFVVGTVGNSVTLFTLARKKSLQSTVDYYLGSLALSDLLILLLAMPVELYNFIWVHHPWAFAGCRGYYFLRDACTYATALNVVSLSVELYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAIPMLFTMGLQNLSGDGTHPGVCTPI--------VDTATLKVVIQVNTFMSFLFPMLVASILNTVIANKLTVMVHQAVVIAFVVCWLPYHVRRLMFCYI-----------SDEQMLTNALVYVSAAINPILYNLVSANFRQVFLST
95tgzA 0.21 0.24 0.92 4.84Download GENFMDIECFMVL----NPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCPSYHFIGSLAVADLLGSVIFVYSFIDFHVFH-RKDSRNVFLFKLGGVTASFTASVGSLFLAAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLG---------NCEK---------LQSVCSDIFHIDKTYLMFWIGVVSVLLLFIVYAYMYILWKAHSHAPDQARELAKTLVLILVVLIICWGPLLAIMVYDVFGKMN-FAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSM
102ydoA 0.17 0.21 0.92 5.41Download ---------------------SSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSAAAADILVGVLAIPFAIA--ISTGFCAACHGCLFIACFVLVLTASSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKAHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQESTLQKEVHAAKSLAIIVGLFALCCFTFFCPDCSHAPLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKI
(a)All the residues are colored in black; however, those residues in template which are identical to the residue in the query sequence are highlighted in color. Coloring scheme is based on the property of amino acids, where polar are brightly coloured while non-polar residues are colored in dark shade. (more about the colors used)
(b)Rank of templates represents the top ten threading templates used by GPCR-I-TASSER.
(c)Ident1 is the percentage sequence identity of the templates in the threading aligned region with the query sequence.
(d)Ident2 is the percentage sequence identity of the whole template chains with query sequence.
(e)Cov. represents the coverage of the threading alignment and is equal to the number of aligned residues divided by the length of query protein.
(f)Norm. Z-score is the normalized Z-score of the threading alignments. Alignment with a Normalized Z-score >1 mean a good alignment and vice versa.
(g)Download Align. provides the 3D structure of the aligned regions of the threading templates.
(h)The top 10 alignments reported above (in order of their ranking) are from the following threading programs:
       1: MUSTER   2: FFAS-3D   3: SPARKS-X   4: HHSEARCH2   5: HHSEARCH I   6: Neff-PPAS   7: HHSEARCH   8: pGenTHREADER   9: wdPPAS   10: cdPPAS   

  Top 5 Models Predicted by GPCR-I-TASSER

Generated 3D models Estimated local accuracy of models
  • Download Model 1
  • C-score=-0.21 (Read more about C-score)
  • Estimated TM-score = 0.69±0.12
  • Estimated RMSD = 6.6±4.0Å

  • Download Model 2
  • C-score = -0.46

  • Download Model 3
  • C-score = -2.59

  • Download Model 4
  • C-score = -2.19

  • Download Model 5
  • C-score = -2.45


    • [Click on Q8NGN8_results.tar.bz2 to download the tarball file including all modeling results listed on this page]