Detailed GPCR-I-TASSER Statistics for Q8NGN7

Submitted Sequence

>sp|Q8NGN7|O10D4_HUMAN
MRNHTMVTEFILLGIPETEGLETALLFLFSSFYLCTLLGNVLILTAIISSTRLHTPMYFF
LGNLSIFDLGFSSTTVPKMLFYLSGNSHAISYAGCVSQLFFYHFLGCTECFLYTVMACDR
FVAICFPLRYTVIMNHRVCFMLATGTWMIGCVHAMILTPLTFQLPYCGPNKVGYYFCDIP
AVLPLACKDTSLAQRVGFTNVGLLSLICFFLILVSYTCIGISISKIRSAEGRQRAFSTCS
AHLTAILCAYGPVIVIYLQPNPSALLGSIIQILNNLVTPMLNPLIYSLRNKDVKSDQP

Predicted Secondary Structure

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                  
Sequence MRNHTMVTEFILLGIPETEGLETALLFLFSSFYLCTLLGNVLILTAIISSTRLHTPMYFFLGNLSIFDLGFSSTTVPKMLFYLSGNSHAISYAGCVSQLFFYHFLGCTECFLYTVMACDRFVAICFPLRYTVIMNHRVCFMLATGTWMIGCVHAMILTPLTFQLPYCGPNKVGYYFCDIPAVLPLACKDTSLAQRVGFTNVGLLSLICFFLILVSYTCIGISISKIRSAEGRQRAFSTCSAHLTAILCAYGPVIVIYLQPNPSALLGSIIQILNNLVTPMLNPLIYSLRNKDVKSDQP
Prediction CCCCCCCHHHSSSCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCSSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHSSCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCSSSSSCCCCCCCCCHHHHHHHHCHHHCCCCHHHCCCCHHHHHHCC
Conf.Score 9988701310132799885089999999999999999989999899971888788489998889998642341388999998606996773899999999999999999999999987508772644457404787499999999999999999999999823789999948885558689988854261099999999999999997999999999999995307652325358762787899699986221037807899875334355777355342013633256588898529

Predicted Solvent Accessibility

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                  
Sequence MRNHTMVTEFILLGIPETEGLETALLFLFSSFYLCTLLGNVLILTAIISSTRLHTPMYFFLGNLSIFDLGFSSTTVPKMLFYLSGNSHAISYAGCVSQLFFYHFLGCTECFLYTVMACDRFVAICFPLRYTVIMNHRVCFMLATGTWMIGCVHAMILTPLTFQLPYCGPNKVGYYFCDIPAVLPLACKDTSLAQRVGFTNVGLLSLICFFLILVSYTCIGISISKIRSAEGRQRAFSTCSAHLTAILCAYGPVIVIYLQPNPSALLGSIIQILNNLVTPMLNPLIYSLRNKDVKSDQP
Prediction 8724130010000000333501100013023313313333310120010033000000110220002002110100020001011643002020020001001310230020001002100000021020002003300000022013102300310030002020026240200000121004000200320022123303331331231023022300100020323612310010000010002012210100000042434221000031023203310300001042136268

Predicted Normalized B-Factor


Read more about predicted normalized B-factor

  Top 10 Templates Used by GPCR-I-TASSER


Rank PDB
Hit
Iden1Iden2Cov.Norm.
Z-score
Download
Align.
                   20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                  
Sec.Str
Seq
CCCCCCCHHHSSSCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCSSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHSSCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCSSSSSCCCCCCCCCHHHHHHHHCHHHCCCCHHHCCCCHHHHHHCC
MRNHTMVTEFILLGIPETEGLETALLFLFSSFYLCTLLGNVLILTAIISSTRLHTPMYFFLGNLSIFDLGFSSTTVPKMLFYLSGNSHAISYAGCVSQLFFYHFLGCTECFLYTVMACDRFVAICFPLRYTVIMNHRVCFMLATGTWMIGCVHAMILTPLTFQLPYCGPNKVGYYFCDIPAVLPLACKDTSLAQRVGFTNVGLLSLICFFLILVSYTCIGISISKIRSAEGRQRAFSTCSAHLTAILCAYGPVIVIYLQPNPSALLGSIIQILNNLVTPMLNPLIYSLRNKDVKSDQP
13emlA 0.18 0.22 0.89 3.55Download ------------------IMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITIST--GFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGGCGEGQVACLFEDVVP-----------MNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLVHAAKSLAIIVGLFALCWLPLHI-INCFTFFCPDCSHLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
25tgzA 0.21 0.24 0.92 2.39Download -ENFMDIECF----MVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRK-DSRNVFLFKLGGVTASFTASVGSLFLAAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAV--------LPLLGWNCEKL---------QSVCSDIFPHDKTYLMFWIGVVSVLLLFIVYAYMYILWKAHSHAPDQARMELAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKFAFCSMLCLLNSTVNPIIYALRSKDLRHAFR
35tgzA 0.21 0.24 0.91 2.29Download GENFMD---------IENPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKD-SRNVFLFKLGGVTASFTASVGSLFLAAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLG----WNCEKLQSV---C---------SDIFPHIDKTYLMFWIGVVSVLLLFIVYAYMYILWKAHSHAPDQARIELAKTLVLILVVLIICWGPLLAIMVKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFR
43uon 0.18 0.20 0.90 1.56Download ------------------TFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIV--GVRTVEDGECYIQFF---------SNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRINISREKKVTRTILAILLAFIITWAPYNVMVLINTPIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFK
54yay 0.19 0.23 0.93 1.24Download TTRNAYIQKYLILNSSDCPYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFF-------IITVCAFHYE--------TLPIGLGLTKNILGFLFPFLIILTSYTLIWKALK------KNDDIFKIIMAIVLFFFFSWIPHQIFTFLDLGDVDTAMPITICIAYFNNCLNPLFYGFLGKKFKRYFL
63emlA 0.18 0.22 0.89 3.73Download -------------------MGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAIT--ISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGGCGEGQVACLFEDVVP-----------MNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLVHAAKSLAIIVGLFALCWLPLHIINCF-TFFCPDCSHAWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
74iaq 0.17 0.23 0.87 1.71Download -----------------SLPWKVLLVMLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASIWHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISISLPPFFW-RQAS----------ECVVN----------TDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRIADARERKATKTLGIILGAFIVCWLPFFIISLVMPIHLAIFD-FFTWLGYLNSLINPIIYTMSNEDFKQAF-
84ea3A 0.20 0.21 0.84 2.67Download -----------------PLGLKVTIVGLYLAVCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLL-TLPFQGTDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPTSSKAQAVNVAIWALASVVGVPVAIMGSAQV---------EDEEIEYWGPVFAICIFLFSF-----------------IVPVLVISVCYSLMIRRLRGVRLLSGSVAVFVGCWTPVQVFVLAQGLGV----QPSSTAVAILRFCTALGYVNSCLNPILYAFLDENFKACFR
93emlA 0.18 0.22 0.89 4.45Download ------------------IMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITIS--TGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLNCGQSQGCGEGQVACLFEDVVP-----------MNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLVHAAKSLAIIVGLFALCWLPLHII-NCFTFFCPDCSHAPLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
102ydoA 0.16 0.21 0.92 5.44Download ---------------------SSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSAAAADILVGVLAIPFAIA--ISTGFCAACHGCLFIACFVLVLTASSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKAHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESTLQKEVHAAKSLAIIVGLFALNCFTFFCPDCSHAPLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
(a)All the residues are colored in black; however, those residues in template which are identical to the residue in the query sequence are highlighted in color. Coloring scheme is based on the property of amino acids, where polar are brightly coloured while non-polar residues are colored in dark shade. (more about the colors used)
(b)Rank of templates represents the top ten threading templates used by GPCR-I-TASSER.
(c)Ident1 is the percentage sequence identity of the templates in the threading aligned region with the query sequence.
(d)Ident2 is the percentage sequence identity of the whole template chains with query sequence.
(e)Cov. represents the coverage of the threading alignment and is equal to the number of aligned residues divided by the length of query protein.
(f)Norm. Z-score is the normalized Z-score of the threading alignments. Alignment with a Normalized Z-score >1 mean a good alignment and vice versa.
(g)Download Align. provides the 3D structure of the aligned regions of the threading templates.
(h)The top 10 alignments reported above (in order of their ranking) are from the following threading programs:
       1: MUSTER   2: FFAS-3D   3: SPARKS-X   4: HHSEARCH2   5: HHSEARCH I   6: Neff-PPAS   7: HHSEARCH   8: pGenTHREADER   9: wdPPAS   10: cdPPAS   

  Top 5 Models Predicted by GPCR-I-TASSER

Generated 3D models Estimated local accuracy of models
  • Download Model 1
  • C-score=0.10 (Read more about C-score)
  • Estimated TM-score = 0.73±0.11
  • Estimated RMSD = 6.0±3.7Å

  • Download Model 2
  • C-score = -2.17

  • Download Model 3
  • C-score = -1.99

  • Download Model 4
  • C-score = -2.80

  • Download Model 5
  • C-score = -0.75


  • [Click on Q8NGN7_results.tar.bz2 to download the tarball file including all modeling results listed on this page]