Detailed GPCR-I-TASSER Statistics for Q8NGJ8

Submitted Sequence

>sp|Q8NGJ8|O51S1_HUMAN
MSTLPTQIAPNSSTSMAPTFLLVGMPGLSGAPSWWTLPLIAVYLLSALGNGTILWIIALQ
PALHRPMHFFLFLLSVSDIGLVTALMPTLLGIALAGAHTVPASACLLQMVFIHVFSVMES
SVLLAMSIDRALAICRPLHYPALLTNGVISKISLAISFRCLGLHLPLPFLLAYMPYCLPQ
VLTHSYCLHPDVARLACPEAWGAAYSLFVVLSAMGLDPLLIFFSYGLIGKVLQGVESRED
RWKAGQTCAAHLSAVLLFYIPMILLALINHPELPITQHTHTLLSYVHFLLPPLINPILYS
VKMKEIRKRILNRLQPRKVGGAQ

Predicted Secondary Structure

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |   
Sequence MSTLPTQIAPNSSTSMAPTFLLVGMPGLSGAPSWWTLPLIAVYLLSALGNGTILWIIALQPALHRPMHFFLFLLSVSDIGLVTALMPTLLGIALAGAHTVPASACLLQMVFIHVFSVMESSVLLAMSIDRALAICRPLHYPALLTNGVISKISLAISFRCLGLHLPLPFLLAYMPYCLPQVLTHSYCLHPDVARLACPEAWGAAYSLFVVLSAMGLDPLLIFFSYGLIGKVLQGVESREDRWKAGQTCAAHLSAVLLFYIPMILLALINHPELPITQHTHTLLSYVHFLLPPLINPILYSVKMKEIRKRILNRLQPRKVGGAQ
Prediction CCCCCCCCCCCCCCCCCHHHSSSCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCSSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCSSSCCCHHHHHHHHHHHHCCCCCCCCC
Conf.Score 98664344789998715112267899986788999999999999999999999888866787543189999999999998998659999999956998788889999999999999999999999981417851666457511888999999999999999999889999944999998957875545365678725675270999999999999989999999999999990788988889987607999999999999999999670389989957999999999727745368011065799999999997166588889

Predicted Solvent Accessibility

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |   
Sequence MSTLPTQIAPNSSTSMAPTFLLVGMPGLSGAPSWWTLPLIAVYLLSALGNGTILWIIALQPALHRPMHFFLFLLSVSDIGLVTALMPTLLGIALAGAHTVPASACLLQMVFIHVFSVMESSVLLAMSIDRALAICRPLHYPALLTNGVISKISLAISFRCLGLHLPLPFLLAYMPYCLPQVLTHSYCLHPDVARLACPEAWGAAYSLFVVLSAMGLDPLLIFFSYGLIGKVLQGVESREDRWKAGQTCAAHLSAVLLFYIPMILLALINHPELPITQHTHTLLSYVHFLLPPLINPILYSVKMKEIRKRILNRLQPRKVGGAQ
Prediction 74423302321323231220200000121320200011022012203321210000020151002000100000020010003002020000000213603040000001200310230120011002000000021010000003310010000002212011202101021021045200000001021002001112201111110033233332310320111002000100146013201100100000000032113310100101331011000100221003003300300002034004100300243425668

Predicted Normalized B-Factor


Read more about predicted normalized B-factor

  Top 10 Templates Used by GPCR-I-TASSER


Rank PDB
Hit		Iden1Iden2Cov.Norm.
Z-score		Download
Align.		                   20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |   
Sec.Str
Seq		CCCCCCCCCCCCCCCCCHHHSSSCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCSSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCSSSCCCHHHHHHHHHHHHCCCCCCCCC
MSTLPTQIAPNSSTSMAPTFLLVGMPGLSGAPSWWTLPLIAVYLLSALGNGTILWIIALQPALHRPMHFFLFLLSVSDIGLVTALMPTLLGIALAGAHTVPASACLLQMVFIHVFSVMESSVLLAMSIDRALAICRPLHYPALLTNGVISKISLAISFRCLGLHLPLPFLLAYMPYCLPQVLTHSYCLHPDVARLACPEAWGAAYSLFVVLSAMGLDPLLIFFSYGLIGKVLQGVESREDRWKAGQTCAAHLSAVLLFYIPMILLALINHPELPITQHTHTLLSYVHFLLPPLINPILYSVKMKEIRKRILNRLQPRKVGGAQ
13emlA 0.19 0.21 0.86 2.33Download ---------------------------IM-GSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITIST--GFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGGCGEGQVACLFEDV----------VPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLVHAAKSLAIIVGLFALCWLPLHIINCFTFFC---PDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQ--
25tgzA 0.16 0.21 0.83 2.00Download -----------------------------SQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRRPSYHFIGSLAVADLLGSVIFVYSFIDF-HVFHRKDSRNVFLFKLGGVTASFTASVGSLFLAAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLP--LLGWNCEKLQSVCSDIF-------------PHIDKTYLMFWIGVVSVLLLFIVYAYMYILWKAHSHAPDQARIELAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLLLNSTVNPIIYALRSKDLRHAFRSMF---------
35tgzA 0.15 0.21 0.85 1.94Download -----GGRGENFMDIMVLN---------PSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRRPSYHFIGSLAVADLLGSVIFVYSFIDFH-VFHRKDSRNVFLFKLGGVTASFTASVGSLFLAAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLG----WNCEKLIFPHID-------------------KTYLMFWIGVVSVLLLFIVYAYMYILWKAHSQARMDIELAKTLVLILVVLIICWGPLLAIMVYDVFGK-MNKLIKTVFAFCSMLCNSTVNPIIYALRSKDLRHAFRSMF---------
44ib4 0.17 0.22 0.87 1.51Download -------------------------EEQGNKLHWAALLILMVIIPTIGGNTLVILAVSLEKKLQYATNYFLMSLAVADLLVGLFVMPIALLTIMFAMWPLPLVLCPAWLFLDVLFSTASIWHLCAISVDRYIAIKKPIQANQYNSRATAFIKITVVWLISIGIAIPVPIKGIE-T-----NPNNITCVLTK--------ERFGDFMLFGSLAAFFTPLAIMIVTYFLTIHALQKKAAISNEQRASKVLGIVFFLFLLMWCPFFITNITLVLCDSCNLQMLLEIFVWIGYVSSGVNPLVYTLFNKTFRDAFGRYITCNYR----
53uonA 0.20 0.20 0.85 1.13Download ----------------------------TFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFI--VGVRTVEDGECYIQF--------FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSR----REKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLM--------
63emlA 0.19 0.21 0.86 2.54Download -----------------------------MGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITIST--GFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGGCGEGQVACLFEDVV----------PMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLVHAAKSLAIIVGLFALCWLPLHIINCF---TFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQ--
74iaq 0.18 0.21 0.81 1.69Download ------------------------------WKVLLVMLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASIWHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISISLPPF-FWRQASECVVN----------T---------DHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRIADARERKATKTLG---IILGAFIVCWLPFFIISLVM-PIHLAIFD-FFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFK------
84buoA 0.18 0.20 0.88 2.70Download -----------NSDL--------DVNTDIYSKVLVTAIYLALFVVGTVGNSVTLFTLARKKSLQSTVDYYLGSLALSDLLILLLAMPVELYNFIWVHHPWAFAGCRGYYFLRDACTYATALNVVSLSVELYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAIPMLFTMGLQNLSGDGTHPG------------GDTATLKVVIQVNTFMSFLFPMLVASILNTVIANKLTVMVHQPGRVQALRRGVLVLRAVVIAFVVCWLPYHVRRLMFCYISHYFYMLTNALVYVSAAINPILYNLVSANFRQVFLSTL---------
95tgzA 0.15 0.21 0.88 2.96Download -----GGRGENFMDIEC--FMVLN----PSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRK-DSRNVFLFKLGGVTASFTASVGSLFLAAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLG-------NCEKLQSV-----------CSDIHIDKTYLMFWIGVVSVLLLFIVYAYMYILWKA-APDQARMDIELAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMF---------
104gpoA 0.17 0.22 0.86 4.34Download ---------------------------LQQWEAGMSLLMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVVRGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSLMTRARAKVIICTVWAISALVSFLPIMMHWWRDEDPQALKCYQDPG--------CCDFVTNAYAIASSIISFYIPLLIMIFVALRVYREAKEQVMLMREHKALKTLGIIMGVFTLCWLPFFLVNIVNVFNRDLVPDWLFVAFNWLGYANSAMNPIIYC-RSPDFRKAFKRL----------
(a)All the residues are colored in black; however, those residues in template which are identical to the residue in the query sequence are highlighted in color. Coloring scheme is based on the property of amino acids, where polar are brightly coloured while non-polar residues are colored in dark shade. (more about the colors used)
(b)Rank of templates represents the top ten threading templates used by GPCR-I-TASSER.
(c)Ident1 is the percentage sequence identity of the templates in the threading aligned region with the query sequence.
(d)Ident2 is the percentage sequence identity of the whole template chains with query sequence.
(e)Cov. represents the coverage of the threading alignment and is equal to the number of aligned residues divided by the length of query protein.
(f)Norm. Z-score is the normalized Z-score of the threading alignments. Alignment with a Normalized Z-score >1 mean a good alignment and vice versa.
(g)Download Align. provides the 3D structure of the aligned regions of the threading templates.
(h)The top 10 alignments reported above (in order of their ranking) are from the following threading programs:
       1: MUSTER   2: FFAS-3D   3: SPARKS-X   4: HHSEARCH2   5: HHSEARCH I   6: Neff-PPAS   7: HHSEARCH   8: pGenTHREADER   9: wdPPAS   10: cdPPAS   

  Top 5 Models Predicted by GPCR-I-TASSER

Generated 3D models Estimated local accuracy of models
  • Download Model 1
  • C-score=-0.64 (Read more about C-score)
  • Estimated TM-score = 0.63±0.13
  • Estimated RMSD = 7.8±4.4Å

  • Download Model 2
  • C-score = -2.23

  • Download Model 3
  • C-score = -1.09

  • Download Model 4
  • C-score = -2.20

  • Download Model 5
  • C-score = -1.86


    • [Click on Q8NGJ8_results.tar.bz2 to download the tarball file including all modeling results listed on this page]