Detailed GPCR-I-TASSER Statistics for Q8NGF6

Submitted Sequence

>sp|Q8NGF6|O10W1_HUMAN
MEFVFLAYPSCPELHILSFLGVSLVYGLIITGNILIVVSIHTETCLCTSMYYFLGSLSGI
EICYTAVVVPHILANTLQSEKTITLLGCATQMAFFIALGSADCFLLAAMAYDRYVAICHP
LQYPLLMTLTLCVHLVVASVISGLFLSLQLVAFIFSLPFCQAQGIEHFFCDVPPVMHVVC
AQSHIHEQSVLVAAILAIAVPFFLITTSYTFIVAALLKIHSAAGRHRAFSTCSSHLTVVL
LQYGCCAFMYLCPSSSYNPKQDRFISLVYTLGTPLLNPLIYALRNSEMKGAVGRVLTRNC
LSQNS

Predicted Secondary Structure

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |     
Sequence MEFVFLAYPSCPELHILSFLGVSLVYGLIITGNILIVVSIHTETCLCTSMYYFLGSLSGIEICYTAVVVPHILANTLQSEKTITLLGCATQMAFFIALGSADCFLLAAMAYDRYVAICHPLQYPLLMTLTLCVHLVVASVISGLFLSLQLVAFIFSLPFCQAQGIEHFFCDVPPVMHVVCAQSHIHEQSVLVAAILAIAVPFFLITTSYTFIVAALLKIHSAAGRHRAFSTCSSHLTVVLLQYGCCAFMYLCPSSSYNPKQDRFISLVYTLGTPLLNPLIYALRNSEMKGAVGRVLTRNCLSQNS
Prediction CSSSSSCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCSSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHSSCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCHHHHHHHHHHHHHHHHSSSSCCCCCCCCCCCCSSSSSHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHCCCCCCC
Conf.Score 93899628998627999999999999999998899978887288756748889878999988887206899999856799778489999999999999999999999998650564065444885148879999999999999999999999980548899796788624838878885358719999999999999999799999999999999842866154641542568789979998844640680789999887782899866336742023543046499999999998615566679

Predicted Solvent Accessibility

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |     
Sequence MEFVFLAYPSCPELHILSFLGVSLVYGLIITGNILIVVSIHTETCLCTSMYYFLGSLSGIEICYTAVVVPHILANTLQSEKTITLLGCATQMAFFIALGSADCFLLAAMAYDRYVAICHPLQYPLLMTLTLCVHLVVASVISGLFLSLQLVAFIFSLPFCQAQGIEHFFCDVPPVMHVVCAQSHIHEQSVLVAAILAIAVPFFLITTSYTFIVAALLKIHSAAGRHRAFSTCSSHLTVVLLQYGCCAFMYLCPSSSYNPKQDRFISLVYTLGTPLLNPLIYALRNSEMKGAVGRVLTRNCLSQNS
Prediction 52000000043340101001302331331333332001002003300100011020001102201001203000101166330102002201100010021001000100100000002102000200330000000000110031031101100002003423010000032000200021031002211331233133123103302320000001031463232000000001000101120000000103163346341000031033203300300001142014002200233313468

Predicted Normalized B-Factor


Read more about predicted normalized B-factor

  Top 10 Templates Used by GPCR-I-TASSER


Rank PDB
Hit		Iden1Iden2Cov.Norm.
Z-score		Download
Align.		                   20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |     
Sec.Str
Seq		CSSSSSCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCSSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHSSCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCHHHHHHHHHHHHHHHHSSSSCCCCCCCCCCCCSSSSSHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHCCCCCCC
MEFVFLAYPSCPELHILSFLGVSLVYGLIITGNILIVVSIHTETCLCTSMYYFLGSLSGIEICYTAVVVPHILANTLQSEKTITLLGCATQMAFFIALGSADCFLLAAMAYDRYVAICHPLQYPLLMTLTLCVHLVVASVISGLFLSLQLVAFIFSLPFCQAQGIEHFFCDVPPVMHVVCAQSHIHEQSVLVAAILAIAVPFFLITTSYTFIVAALLKIHSAAGRHRAFSTCSSHLTVVLLQYGCCAFMYLCPSSSYNPKQDRFISLVYTLGTPLLNPLIYALRNSEMKGAVGRVLTRNCLSQNS
13emlA 0.23 0.24 0.91 3.72Download -----------IMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTG--FCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGGCGEGQVACLFEDVVP-----------MNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLVHAAKSLAIIVGLFALCWLPLHIINC-FTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQ--
25tgzA 0.19 0.23 0.88 2.16Download ----------NPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRK-DSRNVFLFKLGGVTASFTASVGSLFLAAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAV--------LPLLGWNCEKL---------QSVCSDIFPHDKTYLMFWIGVVSVLLLFIVYAYMYILWKAHSHAPDQARMELAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFSMLCLLNSTVNPIIYALRSKDLRHAFRSM----------
34iaqA 0.16 0.20 0.86 2.17Download ---YIYQDSISLPWKVLLVMLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGR----WVVCDFWLSSDITCCTASIWHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISISL---------PPCVVNTDH-----------------ILYTVYSTVGAF---YFPTLLLIALYGRIYVEARSRIIQKYAARERKATKTLGIILGAFIVCWLPFFIISLVMPIHLAIFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFK------
44djh 0.15 0.25 0.92 1.54Download ----------SPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTT-TMPFQSTVYLMNSWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVR---EDVDVIECSLQFPDD---DYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFP-------
54yay 0.20 0.27 0.90 1.22Download QKYLILNSSDCNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFF-------IITVCAFHYE--------TLPIGLGLTKNILGFLFPFLIILTSYTLIWKALK------KNDDIFKIIMAIVLFFFFSWIPHQIFTFLQLGIDIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKRYFLQLL---------
63emlA 0.23 0.24 0.91 3.87Download ------------MGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAIT--ISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGGCGEGQVACLFEDVVP-----------MNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLVHAAKSLAIIVGLFALCWLPLHIINCF-TFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQ--
74iaq 0.18 0.23 0.86 1.71Download ------------PWKVLLVMLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASIWHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISISLPPFFW-RQASE----------CVVN----------TDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRIADARERKATKTLGIILGAFIVCWLPFFIISLVMPI--HL-AIFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFK------
82z73A 0.13 0.22 0.93 2.34Download REF-----DQVPAVYYSLGIFIGICGIIGCGGNGIVIYLFTKTKSLQTPANMFIINLAFSDFTFSLVNGPLMTISCFLKKWIFGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAASKKMSHRRAFIMIIFVWLWSVLWAIGPIFGTLEGVLCNDYI----------------SRDSTTRSNILCMFILGFFGPILIIFFCYFNIVMAQAGANAEMRLAKISIVIVSQFLLSWSPYAVVALLAQFGPLEWVTPYAAQLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVLTCCQF
93emlA 0.22 0.24 0.91 4.99Download -----------IMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITIS--TGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLNCGQSQGCGEGQVACLFEDVVP-----------MNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLVHAAKSLAII-VGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQ--
102ydoA 0.18 0.23 0.95 6.03Download --------------SSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSAAAADILVGVLAIPFAIA--ISTGFCAACHGCLFIACFVLVLTASSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKAHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESTLQKEVHAAKSLAIIVGLFALCWLTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQE
(a)All the residues are colored in black; however, those residues in template which are identical to the residue in the query sequence are highlighted in color. Coloring scheme is based on the property of amino acids, where polar are brightly coloured while non-polar residues are colored in dark shade. (more about the colors used)
(b)Rank of templates represents the top ten threading templates used by GPCR-I-TASSER.
(c)Ident1 is the percentage sequence identity of the templates in the threading aligned region with the query sequence.
(d)Ident2 is the percentage sequence identity of the whole template chains with query sequence.
(e)Cov. represents the coverage of the threading alignment and is equal to the number of aligned residues divided by the length of query protein.
(f)Norm. Z-score is the normalized Z-score of the threading alignments. Alignment with a Normalized Z-score >1 mean a good alignment and vice versa.
(g)Download Align. provides the 3D structure of the aligned regions of the threading templates.
(h)The top 10 alignments reported above (in order of their ranking) are from the following threading programs:
       1: MUSTER   2: FFAS-3D   3: SPARKS-X   4: HHSEARCH2   5: HHSEARCH I   6: Neff-PPAS   7: HHSEARCH   8: pGenTHREADER   9: wdPPAS   10: cdPPAS   

  Top 5 Models Predicted by GPCR-I-TASSER

Generated 3D models Estimated local accuracy of models
  • Download Model 1
  • C-score=0.21 (Read more about C-score)
  • Estimated TM-score = 0.74±0.11
  • Estimated RMSD = 5.8±3.6Å

  • Download Model 2
  • C-score = -2.38

  • Download Model 3
  • C-score = -2.58

  • Download Model 4
  • C-score = -3.74

  • Download Model 5
  • C-score = -1.56


    • [Click on Q8NGF6_results.tar.bz2 to download the tarball file including all modeling results listed on this page]