Detailed GPCR-I-TASSER Statistics for Q15760

Submitted Sequence

>sp|Q15760|GPR19_HUMAN
MVFAHRMDNSKPHLIIPTLLVPLQNRSCTETATPLPSQYLMELSEEHSWMSNQTDLHYVL
KPGEVATASIFFGILWLFSIFGNSLVCLVIHRSRRTQSTTNYFVVSMACADLLISVASTP
FVLLQFTTGRWTLGSATCKVVRYFQYLTPGVQIYVLLSICIDRFYTIVYPLSFKVSREKA
KKMIAASWVFDAGFVTPVLFFYGSNWDSHCNYFLPSSWEGTAYTVIHFLVGFVIPSVLII
LFYQKVIKYIWRIGTDGRTVRRTMNIVPRTKVKTIKMFLILNLLFLLSWLPFHVAQLWHP
HEQDYKKSSLVFTAITWISFSSSASKPTLYSIYNANFRRGMKETFCMSSMKCYRSNAYTI
TTSSRMAKKNYVGISEIPSMAKTITKDSIYDSFDREAKEKKLAWPINSNPPNTFV

Predicted Secondary Structure

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340                 360                 380                 400
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |               
Sequence MVFAHRMDNSKPHLIIPTLLVPLQNRSCTETATPLPSQYLMELSEEHSWMSNQTDLHYVLKPGEVATASIFFGILWLFSIFGNSLVCLVIHRSRRTQSTTNYFVVSMACADLLISVASTPFVLLQFTTGRWTLGSATCKVVRYFQYLTPGVQIYVLLSICIDRFYTIVYPLSFKVSREKAKKMIAASWVFDAGFVTPVLFFYGSNWDSHCNYFLPSSWEGTAYTVIHFLVGFVIPSVLIILFYQKVIKYIWRIGTDGRTVRRTMNIVPRTKVKTIKMFLILNLLFLLSWLPFHVAQLWHPHEQDYKKSSLVFTAITWISFSSSASKPTLYSIYNANFRRGMKETFCMSSMKCYRSNAYTITTSSRMAKKNYVGISEIPSMAKTITKDSIYDSFDREAKEKKLAWPINSNPPNTFV
Prediction CCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCSSCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSSCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSCCSSSSSCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCC
Conf.Score 9511210135787787744265668888987889986210256766566678876455788589999999999999999997887713214078888544799999999999999998999999998172107458898799999999999999999999873520105777643366688843799999999999999825230144010126871133899999999999999999999999999999342698865304566888998899999999999999998999999999996337775489999999999999999999999739999999999848777787777876768775213678776536899876755887666777611110446789999998869

Predicted Solvent Accessibility

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340                 360                 380                 400
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Sequence MVFAHRMDNSKPHLIIPTLLVPLQNRSCTETATPLPSQYLMELSEEHSWMSNQTDLHYVLKPGEVATASIFFGILWLFSIFGNSLVCLVIHRSRRTQSTTNYFVVSMACADLLISVASTPFVLLQFTTGRWTLGSATCKVVRYFQYLTPGVQIYVLLSICIDRFYTIVYPLSFKVSREKAKKMIAASWVFDAGFVTPVLFFYGSNWDSHCNYFLPSSWEGTAYTVIHFLVGFVIPSVLIILFYQKVIKYIWRIGTDGRTVRRTMNIVPRTKVKTIKMFLILNLLFLLSWLPFHVAQLWHPHEQDYKKSSLVFTAITWISFSSSASKPTLYSIYNANFRRGMKETFCMSSMKCYRSNAYTITTSSRMAKKNYVGISEIPSMAKTITKDSIYDSFDREAKEKKLAWPINSNPPNTFV
Prediction 6323330453533321121131034331341112223320332344433332333232312200100102211200210130010000000023402000000020001001010000010100010033011010000000000000000000000000000010000002132133100000000001000000000000204332201010126303200000001210330010002000000010233334354454444434422100000000000000000211000000101144241010000000100020000000000000630040013002013232344443434444444444433344343444333443335534463554435353564345324

Predicted Normalized B-Factor


Read more about predicted normalized B-factor

  Top 10 Templates Used by GPCR-I-TASSER


Rank PDB
Hit		Iden1Iden2Cov.Norm.
Z-score		Download
Align.		                   20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340                 360                 380                 400
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Sec.Str
Seq		CCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCSSCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSSCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSCCSSSSSCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCC
MVFAHRMDNSKPHLIIPTLLVPLQNRSCTETATPLPSQYLMELSEEHSWMSNQTDLHYVLKPGEVATASIFFGILWLFSIFGNSLVCLVIHRSRRTQSTTNYFVVSMACADLLISVASTPFVLLQFTTGRWTLGSATCKVVRYFQYLTPGVQIYVLLSICIDRFYTIVYPLSFKVSREKAKKMIAASWVFDAGFVTPVLFFYGSNWDSHCNYFLPSSWEGTAYTVIHFLVGFVIPSVLIILFYQKVIKYIWRIGTDGRTVRRTMNIVPRTKVKTIKMFLILNLLFLLSWLPFHVAQLWHPHEQDYKKSSLVFTAITWISFSSSASKPTLYSIYNANFRRGMKETFCMSSMKCYRSNAYTITTSSRMAKKNYVGISEIPSMAKTITKDSIYDSFDREAKEKKLAWPINSNPPNTFV
14n6hA 0.19 0.19 0.70 2.51Download ----------------------------------------------------SPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLM--TWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRAVVCMLFPSPYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGS-----KEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCG-----------------------------------------------------------------
24n6hA 0.20 0.21 0.70 3.55Download ---------------------------------------------------GSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALA-TSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALRTPAKAKLINICIWVLASGVGVPIMVMAVTDGAVVCMLQFPSPYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGS-----KEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKP-------------------------------------------------------------------
34n6hA 0.20 0.19 0.70 3.35Download ----------------------------------------------------SPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATST-LPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALRTPAKAKLINICIWVLASGVGVPIMVMAVTDGAVVCMLQFPSPYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSK-----EKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCG-----------------------------------------------------------------
42ziy 0.20 0.20 0.84 1.55Download -----------------------------------------DLRDNETWWYNPSIEFDQVPDAVYYSLGIFIGICGIIGCGGNGIVIYLFTKTKSLQTPANMFIINLAFSDFTFSLVGFPLMTISCFLKKWIFGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAASMSHRRAFIMIIFVWLWSVLWAIGPIFGWGAYVLCNCSFDYISRDTTRSNILCMFILGFFGPILIIFFCYFNIVMSVSNHEKEMAAMAKKAQAGANAEMRLAKISIVIVSQFLLSWSPYAVVALLAQFGPLEWVTPYAAQLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVLTCCQFDDKETE--D-DKDA-----ETEIPAGESSDAAPS------ADAAQMKE-------------
54djh 0.20 0.19 0.68 1.16Download ------------------------------------------------------------SPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVT-TTMPFQSTVYLMNSWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALRTPLKAKIINICIWLLSSSVGISAIVLGGTKDVIECSLQFPDDDWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGNTKPNYREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSA---ALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFP--------------------------------------------------------------------
64n6hA 0.18 0.21 0.83 3.01Download PEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLGSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALA-TSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRVVCMLQFPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGS-----KEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCG-----------------------------------------------------------------
73uon 0.26 0.24 0.67 1.73Download ----------------------------------------------------------------VVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPRTTKMAGMMIAAAWVLSFILWAPAILFWQFIEDGECYIQFF---SNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRINIFGGATWDAYPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPC-IPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLM---------------------------------------------------------------------
84ea3A 0.22 0.17 0.65 4.10Download ------------------------------------------------------------PLGLKVTIVGLYLAVCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLT-LPFQGTDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPT-----SSKAQAVNVAIWALASVVGVPVAIMQVEDEEIECLVEIPTPYWGPVFAICIFLFSFIVPVLVISVCYSLMIRRLRGVRLLSGS-----REKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSAVAILRFCTALGYVNSCLNPILYAFLDENFKACFR-------------------------------------------------------------------------
94iaqA 0.24 0.17 0.67 2.80Download -----------------------------------------------------YIYQDSISLPWKVLLVMLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASIWHLCVIALDRYWAITDAVEYKRTPKRAAVMIALVWVFSISISLPPFFWRQA---SECVVNTDH----ILYTVYSTVGAFYFPTLLLIALYGRIYVEARSR------IIQKYLLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPIH------LAIFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFK-------------------------------------------------------------------
105dhgA 0.22 0.17 0.66 2.63Download ------------------------------------------------------------PLGLKVTIVGLYLAVCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLT-LPFQGTDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIV--RTSSKAQAVNVAIWALASVVGVPVAIMGSEDEEIECLVEIPTPYWGPVFAICIFLFSFIVPVLVISVCYSLMIRRLRGVRLLSGS-----REKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGPSSETAVAILRFCTALGYVNSCLNPILYAFLDENFKACFR-------------------------------------------------------------------------
(a)All the residues are colored in black; however, those residues in template which are identical to the residue in the query sequence are highlighted in color. Coloring scheme is based on the property of amino acids, where polar are brightly coloured while non-polar residues are colored in dark shade. (more about the colors used)
(b)Rank of templates represents the top ten threading templates used by GPCR-I-TASSER.
(c)Ident1 is the percentage sequence identity of the templates in the threading aligned region with the query sequence.
(d)Ident2 is the percentage sequence identity of the whole template chains with query sequence.
(e)Cov. represents the coverage of the threading alignment and is equal to the number of aligned residues divided by the length of query protein.
(f)Norm. Z-score is the normalized Z-score of the threading alignments. Alignment with a Normalized Z-score >1 mean a good alignment and vice versa.
(g)Download Align. provides the 3D structure of the aligned regions of the threading templates.
(h)The top 10 alignments reported above (in order of their ranking) are from the following threading programs:
       1: MUSTER   2: FFAS-3D   3: SPARKS-X   4: HHSEARCH2   5: HHSEARCH I   6: Neff-PPAS   7: HHSEARCH   8: pGenTHREADER   9: wdPPAS   10: cdPPAS   

  Top 5 Models Predicted by GPCR-I-TASSER

Generated 3D models Estimated local accuracy of models
  • Download Model 1
  • C-score=-0.98 (Read more about C-score)
  • Estimated TM-score = 0.59±0.14
  • Estimated RMSD = 9.1±4.6Å

  • Download Model 2
  • C-score = -1.79

  • Download Model 3
  • C-score = -1.18

  • Download Model 4
  • C-score = -3.19

  • Download Model 5
  • C-score = -2.13


    • [Click on Q15760_results.tar.bz2 to download the tarball file including all modeling results listed on this page]