Detailed GPCR-I-TASSER Statistics for P59536

Submitted Sequence

>sp|P59536|T2R41_HUMAN
MQAALTAFFVLLFSLLSLLGIAANGFIVLVLGREWLRYGRLLPLDMILISLGASRFCLQL
VGTVHNFYYSAQKVEYSGGLGRQFFHLHWHFLNSATFWFCSWLSVLFCVKIANITHSTFL
WLKWRFPGWVPWLLLGSVLISFIITLLFFWVNYPVYQEFLIRKFSGNMTYKWNTRIETYY
FPSLKLVIWSIPFSVFLVSIMLLINSLRRHTQRMQHNGHSLQDPSTQAHTRALKSLISFL
ILYALSFLSLIIDAAKFISMQNDFYWPWQIAVYLCISVHPFILIFSNLKLRSVFSQLLLL
ARGFWVA

Predicted Secondary Structure

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |       
Sequence MQAALTAFFVLLFSLLSLLGIAANGFIVLVLGREWLRYGRLLPLDMILISLGASRFCLQLVGTVHNFYYSAQKVEYSGGLGRQFFHLHWHFLNSATFWFCSWLSVLFCVKIANITHSTFLWLKWRFPGWVPWLLLGSVLISFIITLLFFWVNYPVYQEFLIRKFSGNMTYKWNTRIETYYFPSLKLVIWSIPFSVFLVSIMLLINSLRRHTQRMQHNGHSLQDPSTQAHTRALKSLISFLILYALSFLSLIIDAAKFISMQNDFYWPWQIAVYLCISVHPFILIFSNLKLRSVFSQLLLLARGFWVA
Prediction CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHSSSCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSSSCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCSSSSSSCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCC
Conf.Score 9748999999999999999999999999999999980798886779999999999999999987066032153211551799999999999939999999999999835641789779999998622309999999999999999999974012013420246787068874230689999999999999999999999999999999999986188999999980899999999999999999999999999999844453999999999999788858999618749999999999865570039

Predicted Solvent Accessibility

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |       
Sequence MQAALTAFFVLLFSLLSLLGIAANGFIVLVLGREWLRYGRLLPLDMILISLGASRFCLQLVGTVHNFYYSAQKVEYSGGLGRQFFHLHWHFLNSATFWFCSWLSVLFCVKIANITHSTFLWLKWRFPGWVPWLLLGSVLISFIITLLFFWVNYPVYQEFLIRKFSGNMTYKWNTRIETYYFPSLKLVIWSIPFSVFLVSIMLLINSLRRHTQRMQHNGHSLQDPSTQAHTRALKSLISFLILYALSFLSLIIDAAKFISMQNDFYWPWQIAVYLCISVHPFILIFSNLKLRSVFSQLLLLARGFWVA
Prediction 7433233311332331233133202200210111004434031011000000211010010133310000000321333210000101123312300100000010000000213110000013304310011023123333311211113233233333344341100131314332201111333333333331332332011002202430343353441231410220010012022223323311321111223342201021113002102300000021143014001300210210018

Predicted Normalized B-Factor


Read more about predicted normalized B-factor

  Top 10 Templates Used by GPCR-I-TASSER


Rank PDB
Hit		Iden1Iden2Cov.Norm.
Z-score		Download
Align.		                   20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |       
Sec.Str
Seq		CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHSSSCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSSSCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCSSSSSSCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCC
MQAALTAFFVLLFSLLSLLGIAANGFIVLVLGREWLRYGRLLPLDMILISLGASRFCLQLVGTVHNFYYSAQKVEYSGGLGRQFFHLHWHFLNSATFWFCSWLSVLFCVKIANITHSTFLWLKWRFPGWVPWLLLGSVLISFIITLLFFWVNYPVYQEFLIRKFSGNMTYKWNTRIETYYFPSLKLVIWSIPFSVFLVSIMLLINSLRRHTQRMQHNGHSLQDPSTQAHTRALKSLISFLILYALSFLSLIIDAAKFISMQNDFYWPWQIAVYLCISVHPFILIFSNLKLRSVFSQLLLLARGFWVA
14djhA 0.11 0.18 0.90 1.36Download -SPAIPVIITAVYSVVFVVGLVGNSLVMFVIIR----TKMKTATNIYIFNLALADALVTTTMPFQSTVYLMN-SWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKA----LDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVRE---DVDVIECSLQFYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSDR-----------NLRRITRLVLVVVAVFVVCWTPIHIFILVEALGALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFP-------
25tjvA 0.11 0.20 0.89 2.75Download LNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHS--RSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRN-VFLFKLGGVTASFTASVGSLFLAAIDRYISIHRPLA----YKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHID---------ETYLMFWIGVTSVLLLFIVYAYMYILWKAGKRAMSFSD--------QARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMF---------
34n6hA 0.11 0.20 0.92 2.14Download SSLALAIAITALYSAVCAVGLLGNVLVMFGIVRY--TKMK-TATNIYIFNLALADALATST--LPFQSAKYLMTWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKA----LDFRTPAKAKLINICIWVLASGVGVPIMVMA-------VTRPRDGAVVCMLQPSWYWDTVTKICVFLFVVPILIITVCYGLMLLRLRSV-----RLLSGSK-EKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCG----
44djh 0.10 0.16 0.95 1.56Download -SPAIPVIITAVYSVVFVVGLVGNSLVMFVIIR---YTKMKTATNIYIFNLALADALVTTT-MPFQSTVYLMNSWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKAL----DFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGNIFTPAYREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEAGSAALSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFP-------
55glh 0.11 0.20 0.90 1.19Download IKETFKYINTVVSCLVFVLGIIGNSTLLYIIYK--------NGPNILIASLALGDLLHIVIAIPINVYKLLAEDWPFGAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASW--------------WTAVEIVLIWVVSVVLAVPEAIGFDIITMD-YKGSYLRICLLHPVQKAFMQFYWWLFSFYFCLPLAITAFFYTLMTCEMLRKNEGLRLTWDAYLNDHLKQRREVAKTVFCLVLVFALCWLPLHLARILKTLYNNVLDYIGINMASLNSCANPIALYLVSKRFKNAFKSAL---------
64djhA 0.11 0.18 0.90 1.51Download -SPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRY---TKMKTATNIYIFNLALADALVTTTMPFQSTVYLMN-SWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKA----LDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVRE---DVDVIECSLQFPSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSD-----------RNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFP-------
73uon 0.11 0.18 0.92 1.72Download -----VVFIVLVAGSLSLVTIIGNILVMVSIKV---NRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRT--VEDGECYIQ----FFS--NAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRINIFEADAYPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLM--------
84n6hA 0.12 0.20 0.92 2.92Download SSLALAIAITALYSAVCAVGLLGNVLVMFGIVRY---TKMKTATNIYIFNLALADALATST-LPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVK----ALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRD-------GAVVCMLQFYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSV------RLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCG----
94djhA 0.11 0.18 0.90 1.47Download -SPAIPVIITAVYSVVFVVGLVGNSLVMFVIIR----TKMKTATNIYIFNLALADALVTTTMPFQSTVYLMN-SWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKA----LDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIE---CSLQFPDDWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLL------------DRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSASSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFP-------
101l9hA 0.14 0.18 0.93 1.71Download AEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQ----HKKLTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCPMSNFRFG------ENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVF----------TVKEAAAATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCCGKNPLGD
(a)All the residues are colored in black; however, those residues in template which are identical to the residue in the query sequence are highlighted in color. Coloring scheme is based on the property of amino acids, where polar are brightly coloured while non-polar residues are colored in dark shade. (more about the colors used)
(b)Rank of templates represents the top ten threading templates used by GPCR-I-TASSER.
(c)Ident1 is the percentage sequence identity of the templates in the threading aligned region with the query sequence.
(d)Ident2 is the percentage sequence identity of the whole template chains with query sequence.
(e)Cov. represents the coverage of the threading alignment and is equal to the number of aligned residues divided by the length of query protein.
(f)Norm. Z-score is the normalized Z-score of the threading alignments. Alignment with a Normalized Z-score >1 mean a good alignment and vice versa.
(g)Download Align. provides the 3D structure of the aligned regions of the threading templates.
(h)The top 10 alignments reported above (in order of their ranking) are from the following threading programs:
       1: MUSTER   2: FFAS-3D   3: SPARKS-X   4: HHSEARCH2   5: HHSEARCH I   6: Neff-PPAS   7: HHSEARCH   8: pGenTHREADER   9: wdPPAS   10: cdPPAS   

  Top 5 Models Predicted by GPCR-I-TASSER

Generated 3D models Estimated local accuracy of models
  • Download Model 1
  • C-score=-0.14 (Read more about C-score)
  • Estimated TM-score = 0.70±0.12
  • Estimated RMSD = 6.5±3.9Å

  • Download Model 2
  • C-score = -2.97

  • Download Model 3
  • C-score = -2.92

  • Download Model 4
  • C-score = -1.36

  • Download Model 5
  • C-score = -0.95


    • [Click on P59536_results.tar.bz2 to download the tarball file including all modeling results listed on this page]