Detailed GPCR-I-TASSER Statistics for P43119

Submitted Sequence

>sp|P43119|PI2R_HUMAN
MADSCRNLTYVRGSVGPATSTLMFVAGVVGNGLALGILSARRPARPSAFAVLVTGLAATD
LLGTSFLSPAVFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLA
LSHPYLYAQLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRMRWAQPG
GAAFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQQKRHQGSLGPRPRTGEDEVDHLIL
LALMTVVMAVCSLPLTIRCFTQAVAPDSSSEMGDLLAFRFYAFNPILDPWVFILFRKAVF
QRLKLWVCCLCLGPAHGDSQTPLSQLASGRRDPRAPSAPVGKEGSCVPLSAWGEGQVEPL
PPTQQSSGSAVGTSSKAEASVACSLC

Predicted Secondary Structure

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340                 360                 380
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Sequence MADSCRNLTYVRGSVGPATSTLMFVAGVVGNGLALGILSARRPARPSAFAVLVTGLAATDLLGTSFLSPAVFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYLYAQLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRMRWAQPGGAAFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQQKRHQGSLGPRPRTGEDEVDHLILLALMTVVMAVCSLPLTIRCFTQAVAPDSSSEMGDLLAFRFYAFNPILDPWVFILFRKAVFQRLKLWVCCLCLGPAHGDSQTPLSQLASGRRDPRAPSAPVGKEGSCVPLSAWGEGQVEPLPPTQQSSGSAVGTSSKAEASVACSLC
Prediction CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHSSSSSSSSCCCCSSSSSCCCCCHHHHHHHHSSSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
Conf.Score 99888874113778999999999999999999984876610788998318999999999999999988999999970444005436986811029999999999999999999998684601444457772687898999899999999999887565358987799469841689961414363003454799999999999999999999987665113343420456789998987116899999999899999999999788866179999999999999999999999978999999999804378999978877888888788888888888766788877888788777079997678999806888666557778789

Predicted Solvent Accessibility

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340                 360                 380
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Sequence MADSCRNLTYVRGSVGPATSTLMFVAGVVGNGLALGILSARRPARPSAFAVLVTGLAATDLLGTSFLSPAVFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYLYAQLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRMRWAQPGGAAFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQQKRHQGSLGPRPRTGEDEVDHLILLALMTVVMAVCSLPLTIRCFTQAVAPDSSSEMGDLLAFRFYAFNPILDPWVFILFRKAVFQRLKLWVCCLCLGPAHGDSQTPLSQLASGRRDPRAPSAPVGKEGSCVPLSAWGEGQVEPLPPTQQSSGSAVGTSSKAEASVACSLC
Prediction 73441532322320001111232133133112100000002243342100000000010001001111000000002332012202101000011010001002000100000000000000001203330222100000000012001002102100010123343010000032532110000001133233212000200000000001112324434444444443243002000000000000100000000000000011231220000001022213333100010001330041023002000324444444344444434454453444444463433424333544244244445243322323346434341432

Predicted Normalized B-Factor


Read more about predicted normalized B-factor

  Top 10 Templates Used by GPCR-I-TASSER


Rank PDB
Hit		Iden1Iden2Cov.Norm.
Z-score		Download
Align.		                   20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340                 360                 380
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Sec.Str
Seq		CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHSSSSSSSSCCCCSSSSSCCCCCHHHHHHHHSSSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
MADSCRNLTYVRGSVGPATSTLMFVAGVVGNGLALGILSARRPARPSAFAVLVTGLAATDLLGTSFLSPAVFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYLYAQLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRMRWAQPGGAAFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQQKRHQGSLGPRPRTGEDEVDHLILLALMTVVMAVCSLPLTIRCFTQAVAPDSSSEMGDLLAFRFYAFNPILDPWVFILFRKAVFQRLKLWVCCLCLGPAHGDSQTPLSQLASGRRDPRAPSAPVGKEGSCVPLSAWGEGQVEPLPPTQQSSGSAVGTSSKAEASVACSLC
14zwjA 0.16 0.18 0.96 2.47Download VVRSPFEAEPWQFSMLAAYMFLLIVLGFPINFLTLYVTVQHKKLR-TPLNYILLNLAVADLFMVLGGFTSTLYTSLH-----GYFVFGPTGCNLQGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRF-GENHAIMGVAFTWVMALACAAPPLAGWSRYIPEGLQCSCGIDYYTLKPNESFVIYMFVVHFTIPMIIIFFCYGQLVFTVKEAAAQQ-------QESATTQKAEKEVTRMVIIYVIAFLICWVPYASVAFYIFTHQSCFGPIFMTIPAFFAKSAAIYNPVIYIMMNKQFRNCMLTTICCGKNVIFKKVSRDKSVTIYLGKRDYVDHVSQVEPVDGLVDPELVKGKKVYVTLTCAFRYGQEDIDVMGLTFRRDLYFS
22ziy 0.14 0.17 0.89 1.52Download YNPSIIQVPDAVYYSLGIFIGICGIIGCGGNGIVIYLFTKTKSLQ-TPANMFIINLAFSDFTFSLVNFPLMTISCFLKKW-----IFGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAASKKMSHRRAFIMIIFVWLWSVLWAIGPIFGWGAYTLEGVLCNCSFDYISRDSTTRSNILMFILGFFGPILIIFFCYFNIVMSVSNHEKEMAAMAKRLRKAQAGANAEMRLAKISIVIVSQFLLSWSPYAVVALLAQFGPLEVTPYAAQLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVLTCCQFDDKETE---DDK---D--AETEIPAGESSDAAPSA-DAAQMKE---------------------------
31gzmA 0.17 0.18 0.76 3.61Download -------AEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLR-TPLNYILLNLAVADLFMVFGGFTTTLYTSLH-----GYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFR-FGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETSFVIYMFVVHFIIPLIVIFFCYGQLVFTVKE-------AAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCCGKN---DD---------------------------------------------------------------------
42ziy 0.13 0.17 0.89 1.15Download YNPSFDQVPDAVYYSLGIFIGICGIIGCGGNGIVIYLFTKTKSLQ-TPANMFIINLAFSDFTFSLVGFPLMTISCF-----LKKWIFGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAASKKMSHRRAFIMIIFVWLWSVLWAIGPIFGWGAYTLEGVLCNCSFDYISRDSTTRSNILMFILGFFGPILIIFFCYFNIVMSVSNHEKEMAAMAKRLRKAQAGANAEMRLAKISIVIVSQFLLSWSPYAVVALLAQFGPLWVTPYAAQLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVLTCCQFDDKETEDDKDAEIPAGESSDAAPSADAAQMKE--------------------------------------
54n6hA 0.16 0.19 0.77 2.85Download SPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMK-TATNIYIFNLALADALATST-LPFQSAKYLMET-----WPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMA-VTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFVVPILIITVCYGLMLLRLRSV--------RLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCG--------------------------------------------------------------------------
62ziyA 0.13 0.17 0.89 2.55Download IVHEFDQVPDAVYYSLGIFIGICGIIGCGGNGIVIYLFTKTKSLQ-TPANMFIINLAFSDFTFSLVNFPLMTISCF-----LKKWIFGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAASKKMSHRRAFIMIIFVWLWSVLWAIGPIFGWGAYTLEGVLCNCSFDYISRDSTTRSNILCMFILFFGPILIIFFCYFNIVMSVSNHEKEMAAMAKRLNKAQAGANAEMRLAKISIVIVSQFLLSWSPYAVVALLAQFGPEWVTPYAAQLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVLTCCQFDDKETEDDKDAET----EIPAGESSDAAPSADAAQMKE--------------------------------
74n6hA 0.15 0.19 0.76 2.78Download --GARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMK-TATNIYIFNLALADALA-TSTLPFQSAKYLMET-----WPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMV-MAVTRPRDGAVVCMLQFPSPSWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSV--------RLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCG--------------------------------------------------------------------------
82ziyA 0.12 0.17 0.89 3.40Download HWREFDQVPDAVYYSLGIFIGICGIIGCGGNGIVIYLFTKTKSLQ-TPANMFIINLAFSDFTFSLVNGPLMTISCFL-----KKWIFGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAASKKMSHRRAFIMIIFVWLWSVLWAIGPIFGWGAYTLEGVLCNCSFDYISRDSTTRSNILCMILGFFGPILIIFFCYFNIVMSVSNHEKEMAAMAKRLNAAQAGANAEMRLAKISIVIVSQFLLSWSPYAVVALLAQFGPEWVTPYAAQLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVLTCCQFDDKETE----DDKDAETEIPAGESSDAAPSADAAQMKE--------------------------------
93uon 0.11 0.20 0.74 1.72Download ------------VVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQ-TVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYW-----PLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGTVEDGECYIQFFSN---AAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRINIFEGGAAGTWDAYPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLM------------------------------------------------------------------------------
101u19A 0.17 0.19 0.83 4.58Download VVRSPFEAPPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLR-TPLNYILLNLAVADLFMVFGGFTTTLYTSLHGY-----FVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRF-GENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETSFVIYMFVVHFIIPLIVIFFCYGQLVFTV-------KEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCCGKNPLGDDEASTTVSKTETSQ---VAPA-------------------------------------------------
(a)All the residues are colored in black; however, those residues in template which are identical to the residue in the query sequence are highlighted in color. Coloring scheme is based on the property of amino acids, where polar are brightly coloured while non-polar residues are colored in dark shade. (more about the colors used)
(b)Rank of templates represents the top ten threading templates used by GPCR-I-TASSER.
(c)Ident1 is the percentage sequence identity of the templates in the threading aligned region with the query sequence.
(d)Ident2 is the percentage sequence identity of the whole template chains with query sequence.
(e)Cov. represents the coverage of the threading alignment and is equal to the number of aligned residues divided by the length of query protein.
(f)Norm. Z-score is the normalized Z-score of the threading alignments. Alignment with a Normalized Z-score >1 mean a good alignment and vice versa.
(g)Download Align. provides the 3D structure of the aligned regions of the threading templates.
(h)The top 10 alignments reported above (in order of their ranking) are from the following threading programs:
       1: MUSTER   2: HHSEARCH2   3: FFAS-3D   4: HHSEARCH I   5: SPARKS-X   6: wdPPAS   7: Neff-PPAS   8: SP3   9: HHSEARCH   10: pGenTHREADER   

  Top 5 Models Predicted by GPCR-I-TASSER

Generated 3D models Estimated local accuracy of models
  • Download Model 1
  • C-score=-0.80 (Read more about C-score)
  • Estimated TM-score = 0.61±0.14
  • Estimated RMSD = 8.5±4.5Å

  • Download Model 2
  • C-score = -1.50

  • Download Model 3
  • C-score = -1.06

  • Download Model 4
  • C-score = -3.45

  • Download Model 5
  • C-score = -0.98


    • [Click on P43119_results.tar.bz2 to download the tarball file including all modeling results listed on this page]