Detailed GPCR-I-TASSER Statistics for P32248

Submitted Sequence

>sp|P32248|CCR7_HUMAN
MDLGKPMKSVLVVALLVIFQVCLCQDEVTDDYIGDNTTVDYTLFESLCSKKDVRNFKAWF
LPIMYSIICFVGLLGNGLVVLTYIYFKRLKTMTDTYLLNLAVADILFLLTLPFWAYSAAK
SWVFGVHFCKLIFAIYKMSFFSGMLLLLCISIDRYVAIVQAVSAHRHRARVLLISKLSCV
GIWILATVLSIPELLYSDLQRSSSEQAMRCSLITEHVEAFITIQVAQMVIGFLVPLLAMS
FCYLVIIRTLLQARNFERNKAIKVIIAVVVVFIVFQLPYNGVVLAQTVANFNITSSTCEL
SKQLNIAYDVTYSLACVRCCVNPFLYAFIGVKFRNDLFKLFKDLGCLSQEQLRQWSSCRH
IRRSSMSVEAETTTTFSP

Predicted Secondary Structure

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340                 360
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                  
Sequence MDLGKPMKSVLVVALLVIFQVCLCQDEVTDDYIGDNTTVDYTLFESLCSKKDVRNFKAWFLPIMYSIICFVGLLGNGLVVLTYIYFKRLKTMTDTYLLNLAVADILFLLTLPFWAYSAAKSWVFGVHFCKLIFAIYKMSFFSGMLLLLCISIDRYVAIVQAVSAHRHRARVLLISKLSCVGIWILATVLSIPELLYSDLQRSSSEQAMRCSLITEHVEAFITIQVAQMVIGFLVPLLAMSFCYLVIIRTLLQARNFERNKAIKVIIAVVVVFIVFQLPYNGVVLAQTVANFNITSSTCELSKQLNIAYDVTYSLACVRCCVNPFLYAFIGVKFRNDLFKLFKDLGCLSQEQLRQWSSCRHIRRSSMSVEAETTTTFSP
Prediction CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHSSSSCCCCCSSSSSCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
Conf.Score 998884288899999998454037788876666787876887676778632248789988999999999999988998678777287768699999999999999999989999999468997777889999999999999999999999998368876415223256841276999999999999999989999751377589867998368970779999999999999999999999999999999842688667617999999999999997899999999999983678887159999999999999999999989899999408889999999974346775134567788888888988888998888997

Predicted Solvent Accessibility

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340                 360
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                  
Sequence MDLGKPMKSVLVVALLVIFQVCLCQDEVTDDYIGDNTTVDYTLFESLCSKKDVRNFKAWFLPIMYSIICFVGLLGNGLVVLTYIYFKRLKTMTDTYLLNLAVADILFLLTLPFWAYSAAKSWVFGVHFCKLIFAIYKMSFFSGMLLLLCISIDRYVAIVQAVSAHRHRARVLLISKLSCVGIWILATVLSIPELLYSDLQRSSSEQAMRCSLITEHVEAFITIQVAQMVIGFLVPLLAMSFCYLVIIRTLLQARNFERNKAIKVIIAVVVVFIVFQLPYNGVVLAQTVANFNITSSTCELSKQLNIAYDVTYSLACVRCCVNPFLYAFIGVKFRNDLFKLFKDLGCLSQEQLRQWSSCRHIRRSSMSVEAETTTTFSP
Prediction 853734234020210220010003333233313342332314335320436314400000002001200120232321000000102331000000000001000000000000000002001003001110100122111000000000031010000001302422331011000000001100000010000002024476421010103263320110011121110232102102200000001023154453300000000000001001220000000100231312344142230010000001000120002100000000440141014002410323445344444464343444446454444447

Predicted Normalized B-Factor


Read more about predicted normalized B-factor

  Top 10 Templates Used by GPCR-I-TASSER


Rank PDB
Hit		Iden1Iden2Cov.Norm.
Z-score		Download
Align.		                   20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340                 360
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                  
Sec.Str
Seq		CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHSSSSCCCCCSSSSSCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
MDLGKPMKSVLVVALLVIFQVCLCQDEVTDDYIGDNTTVDYTLFESLCSKKDVRNFKAWFLPIMYSIICFVGLLGNGLVVLTYIYFKRLKTMTDTYLLNLAVADILFLLTLPFWAYSAAKSWVFGVHFCKLIFAIYKMSFFSGMLLLLCISIDRYVAIVQAVSAHRHRARVLLISKLSCVGIWILATVLSIPELLYSDLQRSSSEQAMRCSLITEHVEAFITIQVAQMVIGFLVPLLAMSFCYLVIIRTLLQARNFERNKAIKVIIAVVVVFIVFQLPYNGVVLAQTVANFNITSSTCELSKQLNIAYDVTYSLACVRCCVNPFLYAFIGVKFRNDLFKLFKDLGCLSQEQLRQWSSCRHIRRSSMSVEAETTTTFSP
14mbsA 0.37 0.30 0.78 3.12Download ----------------------------------------------PCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINYKRLKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAVVHAVFALKARTVT--FGVVTSVITWVVAVFASLPNIIFTRSQKEGLHYTCSSHFPYSQYFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRMKEKKRHRDVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLN-NCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEEFRNYLLVFFQ------------------------------------
24mbsA 0.37 0.29 0.78 4.30Download ----------------------------------------------PCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINYKRLKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAVVHAVFALKART--VTFGVVTSVITWVVAVFASLPNIIFTRSQKEGLHYTCSSHFPYSQYQWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLREEEKKRHRDVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLN-NCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEEFRNYLLVFFQ------------------------------------
34mbsA 0.37 0.30 0.78 3.84Download ----------------------------------------------PCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINYKRLKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAVVHAVFALKARTV--TFGVVTSVITWVVAVFASLPNIIFTRSQKEGLHYTCSSHFPYQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRMKEKKRHRDVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNN-CSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEEFRNYLLVFFQ------------------------------------
44djh 0.26 0.25 0.73 1.53Download -----------------------------------------------------SPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYMNSWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFR--TPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSA------------ALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFP-----------------------------------
55t1a 0.38 0.30 0.75 1.17Download ----------------------------------------------------VKQIGAQLLPPLYSLVFIFGFVGNMLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAHSAANEWVFGNAMCKLFTGLYHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVT--FGVVTSVITWLVAVFASVPGIIFTKQKE-D--SVYVCGPYFPRG-WNNFHTIMRNILGLVLPLLIMVICYSGISRASKSRIPSREKKAVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFG-LSNCESTSQLDQATQVTETLGMTHCCINPIIYAFVGEKFRRYLSVFF-------------------------------------
64mbsA 0.37 0.30 0.77 3.25Download -----------------------------------------------CQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINYKRLKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAVVHAVFALKART--VTFGVVTSVITWVVAVFASLPNIIFTRSQKEGLHYTCSSHFPYSYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRMKEKKRHRDVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLN-NCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEEFRNYLLVFFQ------------------------------------
75t1a 0.38 0.30 0.74 1.72Download ------------------------------------------------------QIGAQLLPPLYSLVFIFGFVGNMLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAHSAANEWVFGNAMCKLFTGLYHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTF--GVVTSVITWLVAVFASVPGIIFTKQKED---SVYVCGPYFPRG-WNNFHTIMRNILGLVLPLLIMVICYSGISRASKSRIPSREKKAVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFG-LSNCESTSQLDQATQVTETLGMTHCCINPIIYAFVGEKFRRYLSVFF-------------------------------------
84mbsA 0.37 0.29 0.77 4.86Download ----------------------------------------------PCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINYKRLKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAVVHAVFALKART--VTFGVVTSVITWVVAVFASLPNIIFTRSQKEGLHYTCSSHFPYSQQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLREK--KRHRDVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNN-CSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEEFRNYLLVFFQ------------------------------------
94mbsA 0.37 0.30 0.78 3.51Download ----------------------------------------------PCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINYKRLKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAVVHAVFALKART--VTFGVVTSVITWVVAVFASLPNIIFTRSQKEGLHYTCSSHFPYSQQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRMKEEEKHRDVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLN-NCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEEFRNYLLVFFQ------------------------------------
105c1mA 0.27 0.22 0.76 3.79Download ------------------------------------------GSHSLPQTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRT--PRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSLRRITRMVLVVVAVFIVCWTPIHIYVIIKAL-------ITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCF-----------------------------------------
(a)All the residues are colored in black; however, those residues in template which are identical to the residue in the query sequence are highlighted in color. Coloring scheme is based on the property of amino acids, where polar are brightly coloured while non-polar residues are colored in dark shade. (more about the colors used)
(b)Rank of templates represents the top ten threading templates used by GPCR-I-TASSER.
(c)Ident1 is the percentage sequence identity of the templates in the threading aligned region with the query sequence.
(d)Ident2 is the percentage sequence identity of the whole template chains with query sequence.
(e)Cov. represents the coverage of the threading alignment and is equal to the number of aligned residues divided by the length of query protein.
(f)Norm. Z-score is the normalized Z-score of the threading alignments. Alignment with a Normalized Z-score >1 mean a good alignment and vice versa.
(g)Download Align. provides the 3D structure of the aligned regions of the threading templates.
(h)The top 10 alignments reported above (in order of their ranking) are from the following threading programs:
       1: MUSTER   2: FFAS-3D   3: SPARKS-X   4: HHSEARCH2   5: HHSEARCH I   6: Neff-PPAS   7: HHSEARCH   8: pGenTHREADER   9: wdPPAS   10: cdPPAS   

  Top 5 Models Predicted by GPCR-I-TASSER

Generated 3D models Estimated local accuracy of models
  • Download Model 1
  • C-score=-0.54 (Read more about C-score)
  • Estimated TM-score = 0.64±0.13
  • Estimated RMSD = 7.9±4.4Å

  • Download Model 2
  • C-score = -1.19

  • Download Model 3
  • C-score = -3.08

  • Download Model 4
  • C-score = -2.36

  • Download Model 5
  • C-score = -3.78


    • [Click on P32248_results.tar.bz2 to download the tarball file including all modeling results listed on this page]