Detailed GPCR-I-TASSER Statistics for P30968

Submitted Sequence

>sp|P30968|GNRHR_HUMAN
MANSASPEQNQNHCSAINNSIPLMQGNLPTLTLSGKIRVTVTFFLFLLSATFNASFLLKL
QKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYL
KLFSMYAPAFMMVVISLDRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQLYIFRM
IHLADSSGQTKVFSQCVTHCSFSQWWHQAFYNFFTFSCLFIIPLFIMLICNAKIIFTLTR
VLHQDPHELQLNQSKNNIPRARLKTLKMTVAFATSFTVCWTPYYVLGIWYWFDPEMLNRL
SDPVNHFFFLFAFLNPCFDPLIYGYFSL

Predicted Secondary Structure

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |        
Sequence MANSASPEQNQNHCSAINNSIPLMQGNLPTLTLSGKIRVTVTFFLFLLSATFNASFLLKLQKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQLYIFRMIHLADSSGQTKVFSQCVTHCSFSQWWHQAFYNFFTFSCLFIIPLFIMLICNAKIIFTLTRVLHQDPHELQLNQSKNNIPRARLKTLKMTVAFATSFTVCWTPYYVLGIWYWFDPEMLNRLSDPVNHFFFLFAFLNPCFDPLIYGYFSL
Prediction CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCSSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHSSSSSSCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
Conf.Score 9999999767776666788887676778776557999999999999999997887622300101213477788749999999999999999997379999987060534158997899999999999999999999986999764787665422688878899999999999999962667623788761001342258887645899999999999999999999999999999999986067888632011332888998799999999999999997999999999996743143058999999999999999599999983279

Predicted Solvent Accessibility

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |        
Sequence MANSASPEQNQNHCSAINNSIPLMQGNLPTLTLSGKIRVTVTFFLFLLSATFNASFLLKLQKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQLYIFRMIHLADSSGQTKVFSQCVTHCSFSQWWHQAFYNFFTFSCLFIIPLFIMLICNAKIIFTLTRVLHQDPHELQLNQSKNNIPRARLKTLKMTVAFATSFTVCWTPYYVLGIWYWFDPEMLNRLSDPVNHFFFLFAFLNPCFDPLIYGYFSL
Prediction 4513233433433232223323236442331321020102011200220131120000000112313445433000000020003001210200020200010133020030001003101010000001000000000020001002223343001000000012001101000000102324436332300120013021434103100000103231331021002001200010133245354544444444424312100000000000010113231100000100143124302200100001001210013031303124

Predicted Normalized B-Factor


Read more about predicted normalized B-factor

  Top 10 Templates Used by GPCR-I-TASSER


Rank PDB
Hit		Iden1Iden2Cov.Norm.
Z-score		Download
Align.		                   20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |        
Sec.Str
Seq		CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCSSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHSSSSSSCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
MANSASPEQNQNHCSAINNSIPLMQGNLPTLTLSGKIRVTVTFFLFLLSATFNASFLLKLQKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQLYIFRMIHLADSSGQTKVFSQCVTHCSFSQWWHQAFYNFFTFSCLFIIPLFIMLICNAKIIFTLTRVLHQDPHELQLNQSKNNIPRARLKTLKMTVAFATSFTVCWTPYYVLGIWYWFDPEMLNRLSDPVNHFFFLFAFLNPCFDPLIYGYFSL
14n6hA 0.17 0.18 0.86 2.60Download ----------------------SPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMK------TATNIYIFNLALADALATSTLPFQSAKYLM--TWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDG-------AVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGS--------KEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRDPLVVAALHLCIALGYANSSLNPVLYAFLDE
21gzmA 0.15 0.20 0.94 3.79Download MNGTEGPNFPFSNKTGVVRSPFEAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLR------TPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSFRFGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEG-----MQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQES-------ATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQG--SDFGPIFMTIPAFFAKTSAVYNPVIYIMMN-
34n6hA 0.17 0.18 0.87 3.54Download ----------------------SPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMK------TATNIYIFNLALADALATST-LPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDG-------AVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSK--------EKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDE
44ib4 0.18 0.23 0.86 1.54Download ----------------------------EEQGNKLHWAALLILMVIIPTIGGNTLVILAVSL--EK----KLQYATNYFLMSLAVADLLVGLFVMPIALLTIMEAMWPLPLVLCPAWLFLDVLFSTASIWHLCAISVDRYIAIKKPIQANQYRATAFIKITVVWLISIGIAIPVPIKGI-ETN-------PNNITCV----LT-KERFGDFMLFGSLAAFFTPLAIMIVTYFLTIHALQKKAADLEDNWEAIQKYLQTISNEQRASKVLGIVFFLFLLMWCPFFITNITLVLCDSCNQTTLQMLLEIFVWIGYVSSGVNPLVYTLFNK
54djh 0.19 0.23 0.86 1.16Download ------------------------------SPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMK------TATNIYIFNLALADALVT-TTMPFQSTVYLMNSWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVD-----VIECSLQFPDDDSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGNIVIQTPAYREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSA-----ALSSYYFCIALGYTNSSLNPILYAFLDE
64n6hA 0.17 0.18 0.86 2.96Download ------------------------GARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMK------TATNIYIFNLALADALA-TSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDG-------AVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSV--------RLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDE
73uon 0.20 0.23 0.83 1.75Download ------------------------------------FIVLVAGSLSLVTIIGNILVMVSIKVNRHLQ------TVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDG----ECYIQFF-S----NAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRINIFEGGLAATWDAYPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAP---CIPNTVWTIGYWLCYINSTINPACYALCN-
84djhA 0.18 0.23 0.86 3.43Download ------------------------------SPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMK------TATNIYIFNLALADALVTTT-MPFQSTVYLMNSWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDV----IECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGNIFEMLRIDEEKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSAA-----LSSYYFCIALGYTNSSLNPILYAFLDE
94grvA 0.20 0.23 0.86 2.67Download ----------------------NSDLDVNTDIYSKVLVTAIYLALFVVGTVGNSVTLFTLAR-KSLQ------STVHYHLGSLALSDLLILLLAMPVELYNFIWHPWAFGDAGCRGYYFLRDACTYATALNVASLSVARYLAICHPFKAKMSRSRTKKFISAIWLASALLAIPMLFTMGLQNRSADGTH----PGGLVCTPIVDTATVKVVIQVNTFMSFLFPMLVISILNTVIANKLTVMSGSV--------------QALRHGVLVARAVVIAFVVCWLPYHVRRLMFCYISDEQWTFYHYFYMLTNALAYASSAINPILYNLVSV
105c1mA 0.20 0.21 0.88 3.60Download ------------------GSHSLPQTGSPSM-VTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMK------TATNIYIFNLALADALATS-TLPFQSVNYLMGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKAFRTPRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGS-------IDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLK--------SVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDE
(a)All the residues are colored in black; however, those residues in template which are identical to the residue in the query sequence are highlighted in color. Coloring scheme is based on the property of amino acids, where polar are brightly coloured while non-polar residues are colored in dark shade. (more about the colors used)
(b)Rank of templates represents the top ten threading templates used by GPCR-I-TASSER.
(c)Ident1 is the percentage sequence identity of the templates in the threading aligned region with the query sequence.
(d)Ident2 is the percentage sequence identity of the whole template chains with query sequence.
(e)Cov. represents the coverage of the threading alignment and is equal to the number of aligned residues divided by the length of query protein.
(f)Norm. Z-score is the normalized Z-score of the threading alignments. Alignment with a Normalized Z-score >1 mean a good alignment and vice versa.
(g)Download Align. provides the 3D structure of the aligned regions of the threading templates.
(h)The top 10 alignments reported above (in order of their ranking) are from the following threading programs:
       1: MUSTER   2: FFAS-3D   3: SPARKS-X   4: HHSEARCH2   5: HHSEARCH I   6: Neff-PPAS   7: HHSEARCH   8: pGenTHREADER   9: wdPPAS   10: cdPPAS   

  Top 5 Models Predicted by GPCR-I-TASSER

Generated 3D models Estimated local accuracy of models
  • Download Model 1
  • C-score=-0.46 (Read more about C-score)
  • Estimated TM-score = 0.65±0.13
  • Estimated RMSD = 7.4±4.2Å

  • Download Model 2
  • C-score = -1.46

  • Download Model 3
  • C-score = -1.50

  • Download Model 4
  • C-score = -1.89

  • Download Model 5
  • C-score = -1.05


    • [Click on P30968_results.tar.bz2 to download the tarball file including all modeling results listed on this page]