Detailed GPCR-I-TASSER Statistics for P0C646

Submitted Sequence

>sp|P0C646|O52Z1_HUMAN
MGIPGLEGLHTWISIPFSFMYIVAVAGNIFLIFLIMTERSLHEPMYLFLSMLASADFLLA
TAAAPKVLAILWFHSMDISFGSCVSQMFFIHFIFVAESAILLAMAFDRYVAICYPLRYTI
LTSSAVRKIGIAAVVRSFFICCPFIFLVYRLTYCGRNIIPHSYCEHIARLACGNINVNII
YGLTVALLSTGLDIVLIIISYTMILHSVFQISSWAARFKALSTCGSHICVIFMFYTPAFF
SFLAHRFGGKTIPHHIHILVGSLYVLVPPMLNPIIYGVKTKQIKDRVILLFSPISVC

Predicted Secondary Structure

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                 
Sequence MGIPGLEGLHTWISIPFSFMYIVAVAGNIFLIFLIMTERSLHEPMYLFLSMLASADFLLATAAAPKVLAILWFHSMDISFGSCVSQMFFIHFIFVAESAILLAMAFDRYVAICYPLRYTILTSSAVRKIGIAAVVRSFFICCPFIFLVYRLTYCGRNIIPHSYCEHIARLACGNINVNIIYGLTVALLSTGLDIVLIIISYTMILHSVFQISSWAARFKALSTCGSHICVIFMFYTPAFFSFLAHRFGGKTIPHHIHILVGSLYVLVPPMLNPIIYGVKTKQIKDRVILLFSPISVC
Prediction CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCSSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCSSSSCCHHHHHHHHHHHHCCCCCC
Conf.Score 999995668799999999999999999999999995788753218999999999999899856999999995699867887899999999999999999999998231552046642342488899999999999999999889999973899999944706579999885248368799999999999999899999999999999826888758889854159999999999998999986630468889835899999999738876468112164799999999983277789

Predicted Solvent Accessibility

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                 
Sequence MGIPGLEGLHTWISIPFSFMYIVAVAGNIFLIFLIMTERSLHEPMYLFLSMLASADFLLATAAAPKVLAILWFHSMDISFGSCVSQMFFIHFIFVAESAILLAMAFDRYVAICYPLRYTILTSSAVRKIGIAAVVRSFFICCPFIFLVYRLTYCGRNIIPHSYCEHIARLACGNINVNIIYGLTVALLSTGLDIVLIIISYTMILHSVFQISSWAARFKALSTCGSHICVIFMFYTPAFFSFLAHRFGGKTIPHHIHILVGSLYVLVPPMLNPIIYGVKTKQIKDRVILLFSPISVC
Prediction 741022132020001102201220332121000002115100100020001002001000201002000000020440304000000120031033011001100300000002101000003410010000003213012202101021032045200000001000100033030011100200331333323103201120020002002460132013001001000100323133101000104330021000100331013013300300002034004100300254638

Predicted Normalized B-Factor


Read more about predicted normalized B-factor

  Top 10 Templates Used by GPCR-I-TASSER


Rank PDB
Hit		Iden1Iden2Cov.Norm.
Z-score		Download
Align.		                   20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                 
Sec.Str
Seq		CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCSSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCSSSSCCHHHHHHHHHHHHCCCCCC
MGIPGLEGLHTWISIPFSFMYIVAVAGNIFLIFLIMTERSLHEPMYLFLSMLASADFLLATAAAPKVLAILWFHSMDISFGSCVSQMFFIHFIFVAESAILLAMAFDRYVAICYPLRYTILTSSAVRKIGIAAVVRSFFICCPFIFLVYRLTYCGRNIIPHSYCEHIARLACGNINVNIIYGLTVALLSTGLDIVLIIISYTMILHSVFQISSWAARFKALSTCGSHICVIFMFYTPAFFSFLAHRFGGKTIPHHIHILVGSLYVLVPPMLNPIIYGVKTKQIKDRVILLFSPISVC
13emlA 0.17 0.25 0.93 2.64Download -----IM-GSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITIST--GFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGGCGEGQVACL---------FEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLVHAAKSLAIIVGLFALCWLPLHIINCFTFFC----PDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLR
25tgzA 0.19 0.23 0.91 2.13Download -------SQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRRPSYHFIGSLAVADLLGSVIFVYSFIDF-HVFHRKDSRNVFLFKLGGVTASFTASVGSLFLAAIDRYISIHRPLAYRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSV--------------CSDIFPHIDKTYLMFWIGVVSVLLLFIVYAYMYILWKAHSHAPDQARIELAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMF------
33pblA 0.20 0.21 0.87 1.85Download ------------YALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTG-GVWNFSCCDVFVTLDVMMCTASIWNLCAISIDRYTAVVMPVHYQHGSCRRVALMITAVWVLAFAVSCPLLF--GFNTTCSIS--------------------NPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC----
43uon 0.19 0.25 0.93 1.56Download ----TF--EVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIV--GVRTVEDGECYIQ-------FFSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRINISREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPN-TVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLM-----
52rh1 0.20 0.24 0.94 1.12Download -----DEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYSLLTKNKARVIILMVWIVSGLTSFLPIQM-H---WYRATHQEAINCYA--EETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLNILKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVY-ILLNWIGYVNSGFNPLIYCR-SPDFRIAFQELLCL----
63emlA 0.17 0.25 0.92 2.83Download --------GSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAIT--ISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGGCGEGQVACLFEDVV---------PMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLVHAAKSLAIIVGLFALCWLPLHIINCFTFFC----PDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLR
74iaq 0.20 0.25 0.88 1.69Download -------PWKVLLVMLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASIWHLCVIALDRYWAITDAVEYSARTPKRAAVMIALVWVFSISISLPPFF-WRQASECVVNT------------------DHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRIADARERKATKTLGIILGAFIVCWLPFFIISLVMPIH----L-AI-FDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFK---
84buoA 0.15 0.20 0.95 3.18Download LDVNTDIYSKVLVTAIYLALFVVGTVGNSVTLFTLARKKSLQSTVDYYLGSLALSDLLILLLAMPVELYNFIWVHHPWAFAGCRGYYFLRDACTYATALNVVSLSVELYLAICHPFKAKTLMRSRTKKFISAIWLASALLAIPMLFTMGLQNLSGDGTHPGATLKVVIQVNTFMSFLFPMLVASILNTVIANKLTVMVHQPGRVQALRRGVLVLRAVVIAFVVCWLPYHVRRLMFCYI---------SDEQWTYHYFYMLTNALVYVSAAINPILYNLVSANFRQVFLSTL------
93emlA 0.18 0.25 0.91 3.07Download -----I--GSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISF----CAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYGLVTGTRAKGIIAICWVLSFAIGLTPMLNCGQSQGCGEGQVACLFEDVV----------MNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLVHAAKSLAIIVGLFALCWLPLHIINCFTFF-----PDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLR
104gpoA 0.19 0.22 0.93 4.88Download -----LQQWEAGMSLLMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVVRGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYSLMTRARAKVIICTVWAISALVSFLPIMMHWWRDEDPQALKCYQDPG------CCDFVTNRAYAIASSIISFYIPLLIMIFVALRVYREAKEQVMLMREHKALKTLGIIMGVFTLCWLPFFLVNIVNVFNRDLVP-DWLFVAFNWLGYANSAMNPIIYC-RSPDFRKAFKRL-------
(a)All the residues are colored in black; however, those residues in template which are identical to the residue in the query sequence are highlighted in color. Coloring scheme is based on the property of amino acids, where polar are brightly coloured while non-polar residues are colored in dark shade. (more about the colors used)
(b)Rank of templates represents the top ten threading templates used by GPCR-I-TASSER.
(c)Ident1 is the percentage sequence identity of the templates in the threading aligned region with the query sequence.
(d)Ident2 is the percentage sequence identity of the whole template chains with query sequence.
(e)Cov. represents the coverage of the threading alignment and is equal to the number of aligned residues divided by the length of query protein.
(f)Norm. Z-score is the normalized Z-score of the threading alignments. Alignment with a Normalized Z-score >1 mean a good alignment and vice versa.
(g)Download Align. provides the 3D structure of the aligned regions of the threading templates.
(h)The top 10 alignments reported above (in order of their ranking) are from the following threading programs:
       1: MUSTER   2: FFAS-3D   3: SPARKS-X   4: HHSEARCH2   5: HHSEARCH I   6: Neff-PPAS   7: HHSEARCH   8: pGenTHREADER   9: wdPPAS   10: cdPPAS   

  Top 5 Models Predicted by GPCR-I-TASSER

Generated 3D models Estimated local accuracy of models
  • Download Model 1
  • C-score=0.14 (Read more about C-score)
  • Estimated TM-score = 0.73±0.11
  • Estimated RMSD = 5.9±3.7Å

  • Download Model 2
  • C-score = -0.34

  • Download Model 3
  • C-score = -0.76

  • Download Model 4
  • C-score = -1.19

  • Download Model 5
  • C-score = -3.44


    • [Click on P0C646_results.tar.bz2 to download the tarball file including all modeling results listed on this page]