Detailed GPCR-I-TASSER Statistics for O60883

Submitted Sequence

>sp|O60883|ETBR2_HUMAN
MRWLWPLAVSLAVILAVGLSRVSGGAPLHLGRHRAETQEQQSRSKRGTEDEEAKGVQQYV
PEEWAEYPRPIHPAGLQPTKPLVATSPNPGKDGGTPDSGQELRGNLTGAPGQRLQIQNPL
YPVTESSYSAYAIMLLALVVFAVGIVGNLSVMCIVWHSYYLKSAWNSILASLALWDFLVL
FFCLPIVIFNEITKQRLLGDVSCRAVPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVR
PIERCQSILAKLAVIWVGSMTLAVPELLLWQLAQEPAPTMGTLDSCIMKPSASLPESLYS
LVMTYQNARMWWYFGCYFCLPILFTVTCQLVTWRVRGPPGRKSECRASKHEQCESQLNST
VVGLTVVYAFCTLPENVCNIVVAYLSTELTRQTLDLLGLINQFSTFFKGAITPVLLLCIC
RPLGQAFLDCCCCCCCEECGGASEASAANGSDNKLKTEVSSSIYFHKPRESPPLLPLGTP
C

Predicted Secondary Structure

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340                 360                 380                 400                 420                 440                 460                 480
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   | 
Sequence MRWLWPLAVSLAVILAVGLSRVSGGAPLHLGRHRAETQEQQSRSKRGTEDEEAKGVQQYVPEEWAEYPRPIHPAGLQPTKPLVATSPNPGKDGGTPDSGQELRGNLTGAPGQRLQIQNPLYPVTESSYSAYAIMLLALVVFAVGIVGNLSVMCIVWHSYYLKSAWNSILASLALWDFLVLFFCLPIVIFNEITKQRLLGDVSCRAVPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVRPIERCQSILAKLAVIWVGSMTLAVPELLLWQLAQEPAPTMGTLDSCIMKPSASLPESLYSLVMTYQNARMWWYFGCYFCLPILFTVTCQLVTWRVRGPPGRKSECRASKHEQCESQLNSTVVGLTVVYAFCTLPENVCNIVVAYLSTELTRQTLDLLGLINQFSTFFKGAITPVLLLCICRPLGQAFLDCCCCCCCEECGGASEASAANGSDNKLKTEVSSSIYFHKPRESPPLLPLGTPC
Prediction CCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHSSSSSSCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCSSCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSSCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHSSSSSSSSCCCCCCSSSSSSSCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
Conf.Score 9763337776778886133579998665544456667675555776333544467677876201478888798877889863216899999999998777777877899887765567777766531899999999999999984509660755684587776107988757999999999988999999994986463268887999999999999999999998716125211522535521898999999999999999999998189898514788714799876797543004135567999999999999899999999999999997827888743045889999989999999999999999999999999999984742335699999999999999999999999996599999999999503157877887877677789874105778888888857788878999999

Predicted Solvent Accessibility

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340                 360                 380                 400                 420                 440                 460                 480
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   | 
Sequence MRWLWPLAVSLAVILAVGLSRVSGGAPLHLGRHRAETQEQQSRSKRGTEDEEAKGVQQYVPEEWAEYPRPIHPAGLQPTKPLVATSPNPGKDGGTPDSGQELRGNLTGAPGQRLQIQNPLYPVTESSYSAYAIMLLALVVFAVGIVGNLSVMCIVWHSYYLKSAWNSILASLALWDFLVLFFCLPIVIFNEITKQRLLGDVSCRAVPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVRPIERCQSILAKLAVIWVGSMTLAVPELLLWQLAQEPAPTMGTLDSCIMKPSASLPESLYSLVMTYQNARMWWYFGCYFCLPILFTVTCQLVTWRVRGPPGRKSECRASKHEQCESQLNSTVVGLTVVYAFCTLPENVCNIVVAYLSTELTRQTLDLLGLINQFSTFFKGAITPVLLLCICRPLGQAFLDCCCCCCCEECGGASEASAANGSDNKLKTEVSSSIYFHKPRESPPLLPLGTPC
Prediction 4310000001002213222233453351524443444544544354246454344334223631353231241442433322222122333332223323313111122324334243212323322000000000010002001300100000001123021000000000000000000000100000000320001200300000000000000000000000000000000033333232220000000000000000000000002023242354310000001022622310000000123020000000000200000000000000113334544543445134211000000000000000010000000000000233123100000000000000200000000000004300400130000012344664444333434433343434434434334433343436437

Predicted Normalized B-Factor


Read more about predicted normalized B-factor

  Top 10 Templates Used by GPCR-I-TASSER


Rank PDB
Hit		Iden1Iden2Cov.Norm.
Z-score		Download
Align.		                   20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340                 360                 380                 400                 420                 440                 460                 480
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   | 
Sec.Str
Seq		CCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHSSSSSSCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCSSCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSSCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHSSSSSSSSCCCCCCSSSSSSSCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
MRWLWPLAVSLAVILAVGLSRVSGGAPLHLGRHRAETQEQQSRSKRGTEDEEAKGVQQYVPEEWAEYPRPIHPAGLQPTKPLVATSPNPGKDGGTPDSGQELRGNLTGAPGQRLQIQNPLYPVTESSYSAYAIMLLALVVFAVGIVGNLSVMCIVWHSYYLKSAWNSILASLALWDFLVLFFCLPIVIFNEITKQRLLGDVSCRAVPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVRPIERCQSILAKLAVIWVGSMTLAVPELLLWQLAQEPAPTMGTLDSCIMKPSASLPESLYSLVMTYQNARMWWYFGCYFCLPILFTVTCQLVTWRVRGPPGRKSECRASKHEQCESQLNSTVVGLTVVYAFCTLPENVCNIVVAYLSTELTRQTLDLLGLINQFSTFFKGAITPVLLLCICRPLGQAFLDCCCCCCCEECGGASEASAANGSDNKLKTEVSSSIYFHKPRESPPLLPLGTPC
14n6hA 0.16 0.21 0.84 2.55Download LEDNWETLNDNLKVIEKADN--AAQVKDALTKMRAAALDAQKATPPKLEDKSPDSPEMKDFRHGFDILVGQIDDALKLA----------NEGKVKEAQAAAEQLKTTRNAYIQKYLGSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLM--TWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALD-FRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDG-----AVVCMLQFPSP--------SWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGS--KEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCG---------------------------------------------
24n6hA 0.19 0.21 0.63 3.64Download --------------------------------------------------------------------------------------------------------------------GSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALA-TSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALD-FRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRD-----GAVVCMLQFPSP--------SWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGS--KEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPC----------------------------------------------
34n6hA 0.15 0.21 0.85 3.42Download ----DLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKATPPKLEDKSPDSPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLGSPGA-------RSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATST-LPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFR-TPAKAKLINICIWVLASGVGVPIMVMAVTRPRD-----GAVVCMLQFP-SPS-------WYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGS--KEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCG---------------------------------------------
42ziy 0.12 0.15 0.74 1.50Download -----------------------------------------------------------------------------------------------DLRDNETWWYNPSIIVHPH---WRE-FDQVPDAVYYSLGIFIGICGIIGCGGNGIVIYLFTKTKSLQTPANMFIINLAFSDFTFSLVGFPLMTISCFLKKWIFGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAASKKMSH-RRAFIMIIFVWLWSVLWAIGPIFGWGAYTLEG----VLCNCSFDYISRDST---------TRSNILCMFILGFFGPILIIFFCYFNIVMSVSNHEKEMAAKAQAGANAEMRLAKISIVIVSQFLLSWSPYAVVALLAQFGPLEWV---TPYAAQLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVLCQFDDKETEDD--KDAETEIPA--GESSDAAPSADAAQMKE-----
54n6hA 0.16 0.21 0.84 3.60Download ---EDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKATPPKLEDKSPDSPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLG----------SPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALA-TSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPV-KALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRD-----GAVVCMLQFPSP--------SWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSV--RLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCG---------------------------------------------
64djh 0.19 0.17 0.60 1.17Download -----------------------------------------------------------------------------------------------------------------------------SPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVT-TTMPFQSTVYLMNSWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKAL-DFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVRE---DVDVIECSLQFPDDDYS-------WWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGPNYREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSAA------LSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFP------------------------------------------------
74n6hA 0.14 0.21 0.85 2.86Download -----DLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKATPPKLEDKSPDSPEMKDFRHGFDILVGQIDDALKLANEG------KVKEAQAAAEQLKTTRNAYIQKYLGSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLM--TWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALD-FRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRD-----GAVVCMLQFPSP--------SWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGS--KEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCG---------------------------------------------
84djh 0.17 0.17 0.61 1.72Download ---------------------------------------------------------------------------------------------------------------------------------PVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVT-TTMPFQSTVYLMNSWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLK-AKIINICIWLLSSSVGISAIVLGGTKVRE---DVDVIECSLQFPDDDYDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGNIFEGGRITWDAYREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSA------ALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCF-------------------------------------------------
94n6hA 0.16 0.21 0.85 2.36Download LEDNWETLNDNLKVIE--KADNAAQVKDALTKMRAAALDAQKATPPKLEDKSPDSPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAE----------QLKTTRNAYIQKYLGSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATS-TLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALD-FRTPAKAKLINICIWVLASGVGVPIMVMAVTRPR-----DGAVVCMLQFPSP--------SWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGS--KEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCG---------------------------------------------
104n6hA 0.19 0.17 0.63 3.54Download --------------------------------------------------------------------------------------------------------------------GSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATST-LPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPV-KALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDG-----AVVCMLQFPSP--------SWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGS--KEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCG---------------------------------------------
(a)All the residues are colored in black; however, those residues in template which are identical to the residue in the query sequence are highlighted in color. Coloring scheme is based on the property of amino acids, where polar are brightly coloured while non-polar residues are colored in dark shade. (more about the colors used)
(b)Rank of templates represents the top ten threading templates used by GPCR-I-TASSER.
(c)Ident1 is the percentage sequence identity of the templates in the threading aligned region with the query sequence.
(d)Ident2 is the percentage sequence identity of the whole template chains with query sequence.
(e)Cov. represents the coverage of the threading alignment and is equal to the number of aligned residues divided by the length of query protein.
(f)Norm. Z-score is the normalized Z-score of the threading alignments. Alignment with a Normalized Z-score >1 mean a good alignment and vice versa.
(g)Download Align. provides the 3D structure of the aligned regions of the threading templates.
(h)The top 10 alignments reported above (in order of their ranking) are from the following threading programs:
       1: MUSTER   2: FFAS-3D   3: SPARKS-X   4: HHSEARCH2   5: Neff-PPAS   6: HHSEARCH I   7: wdPPAS   8: HHSEARCH   9: cdPPAS   10: pGenTHREADER   

  Top 5 Models Predicted by GPCR-I-TASSER

Generated 3D models Estimated local accuracy of models
  • Download Model 1
  • C-score=-0.41 (Read more about C-score)
  • Estimated TM-score = 0.66±0.13
  • Estimated RMSD = 8.1±4.4Å

  • Download Model 2
  • C-score = -3.37

  • Download Model 3
  • C-score = -3.04

  • Download Model 4
  • C-score = -3.60

  • Download Model 5
  • C-score = -1.17


    • [Click on O60883_results.tar.bz2 to download the tarball file including all modeling results listed on this page]