Detailed GPCR-I-TASSER Statistics for A6NHA9

Submitted Sequence

>sp|A6NHA9|O4C46_HUMAN
MENRNNMTEFVLLGLTENPKMQKIIFVVFFVIYIITVVGYVLIVVTITASPSLGSPMYLS
LAYLSFIDACYSSVNTPNLITHSLYGKKAILFNGCMTQVFGEHFFGGAEGILLTVMAYDH
YVAICKPLHYMTIMNQCVCALLMGVVWMGGFLHATIQILFIFQLPFCGPNVIDHFMCDLN
PLLNLACTDTHMLELFIAANSGFICLLNFALLLVSYVVILCSLRTHSLEARHKALSTCVS
HITVVILFFVPCIFVYMRPAATLPIDKAVAIFYTMITPMLNPLIYTLKNAQMKNAIRKLC
SRKDISGDK

Predicted Secondary Structure

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |         
Sequence MENRNNMTEFVLLGLTENPKMQKIIFVVFFVIYIITVVGYVLIVVTITASPSLGSPMYLSLAYLSFIDACYSSVNTPNLITHSLYGKKAILFNGCMTQVFGEHFFGGAEGILLTVMAYDHYVAICKPLHYMTIMNQCVCALLMGVVWMGGFLHATIQILFIFQLPFCGPNVIDHFMCDLNPLLNLACTDTHMLELFIAANSGFICLLNFALLLVSYVVILCSLRTHSLEARHKALSTCVSHITVVILFFVPCIFVYMRPAATLPIDKAVAIFYTMITPMLNPLIYTLKNAQMKNAIRKLCSRKDISGDK
Prediction CCCCCCCCSSSSSCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHSSSSSCCCCCCCCHHHHHHHHHHHHHCHHCCCCHHHHHHHHCCCCSSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHSSCCCCCCCCCCCSSCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCSSSSSCCCCCCCCCCCSSHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHCCCCCCC
Conf.Score 999873023477158998024799999999999999997887555232079999978999886998764311467589999874399678499999999999999998999999998651786360011620277759999999999999999999999943189889884777643818878783034142210033333499999999999999999999400373021089989888999353562064358868899987500122455431330103643246199999999999830565679

Predicted Solvent Accessibility

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |         
Sequence MENRNNMTEFVLLGLTENPKMQKIIFVVFFVIYIITVVGYVLIVVTITASPSLGSPMYLSLAYLSFIDACYSSVNTPNLITHSLYGKKAILFNGCMTQVFGEHFFGGAEGILLTVMAYDHYVAICKPLHYMTIMNQCVCALLMGVVWMGGFLHATIQILFIFQLPFCGPNVIDHFMCDLNPLLNLACTDTHMLELFIAANSGFICLLNFALLLVSYVVILCSLRTHSLEARHKALSTCVSHITVVILFFVPCIFVYMRPAATLPIDKAVAIFYTMITPMLNPLIYTLKNAQMKNAIRKLCSRKDISGDK
Prediction 874422000000000042440010000313332332333233000002004304000010023001200110000002000000253210005000000011033113102000200300000002211010000331000001201310230130013102303000112200010022200300002023000300230132023103313311210020013214612220010030021002023210100000033313300010031023003301300002044023003301443133578

Predicted Normalized B-Factor


Read more about predicted normalized B-factor

  Top 10 Templates Used by GPCR-I-TASSER


Rank PDB
Hit		Iden1Iden2Cov.Norm.
Z-score		Download
Align.		                   20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |         
Sec.Str
Seq		CCCCCCCCSSSSSCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHSSSSSCCCCCCCCHHHHHHHHHHHHHCHHCCCCHHHHHHHHCCCCSSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHSSCCCCCCCCCCCSSCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCSSSSSCCCCCCCCCCCSSHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHCCCCCCC
MENRNNMTEFVLLGLTENPKMQKIIFVVFFVIYIITVVGYVLIVVTITASPSLGSPMYLSLAYLSFIDACYSSVNTPNLITHSLYGKKAILFNGCMTQVFGEHFFGGAEGILLTVMAYDHYVAICKPLHYMTIMNQCVCALLMGVVWMGGFLHATIQILFIFQLPFCGPNVIDHFMCDLNPLLNLACTDTHMLELFIAANSGFICLLNFALLLVSYVVILCSLRTHSLEARHKALSTCVSHITVVILFFVPCIFVYMRPAATLPIDKAVAIFYTMITPMLNPLIYTLKNAQMKNAIRKLCSRKDISGDK
13emlA 0.18 0.19 0.89 3.43Download ------------------IMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITIS---GFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGGCGEGQVACLFEDVVPMNYMVYFN-----------FFACVLVPLLLMLGVYLRIFLAARQLVHAAKSLAIIVGLFALCWLPLHII-NCFTFFCPDCSHAWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQ--
25tgzA 0.21 0.25 0.89 2.15Download -ENFMDIECF----MVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKD-SRNVFLFKLGGVTASFTASVGSLFLAAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLL--------GWNCEK---------LQSVCSDIFHIDKTYLMFWIGVVSVLLLFIVYAYMYILWKAHSHAPDQARELAKTLVLILVVLIICWGPLLAIMVKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSM----------
35tgzA 0.19 0.25 0.90 2.17Download -GGRGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKD-SRNVFLFKLGGVTASFTASVGSLFLAAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLCEKLQSVC-------------------SDIFPHIDKTYLMFWIGVVSVLLLFIVYAYMYILWKAHSHAARMDIELAKTLVLILVVLIICWGPLLAIMVGKMNLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMF---------
44ib4 0.16 0.20 0.89 1.54Download ---------------EEQGNKLHWAALLILMVIIPTIGGNTLVILAVSLEKKLQYATNYFLMSLAVADLLVGLFVMPIALLTIMEAMWPLPLVLCPAWLFLDVLFSTASIWHLCAISVDRYIAIKKPIQANQYNSRATAFIKITVVWLISIGIAIPVPIKG--IET-N---PNNITCVLTKE---------RFGDFMLFGSLAAFFTPLAIMIVTYFLTIHALQKKAASNEQRASKVLGIVFFLFLLMWCPFFITNITLVLCDQMLLEIFVWIGYVSSGVNPLVYTLFNKTFRDAFGRYITCNYR----
54yay 0.16 0.23 0.91 1.22Download KTRNAYIQKYLILNSSDCNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFF-------IITVCAFHYE--------TLPIGLGLTKNILGFLFPFLIILTSYTLIWKALK-----KNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKRYFLQLL---------
63emlA 0.18 0.19 0.89 3.54Download -------------------MGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAIT--ISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGGCGEGQVACLFEDVVP-----------MNYMVYFNFFACVLVPLLLMLGVYLRIFLAARQLVHAAKSLAIIVGLFALC-WLPLHIINCFTFFCPDCSHAPLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQ--
74iaq 0.19 0.22 0.85 1.75Download ------------------LPWKVLLVMLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASIWHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISISLPPFF-WRQASECVVN--------------------TDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRIAARERKATKTLGIILGAFIVCWLPFFIISLVMPIH-LAIFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFK------
82z73A 0.15 0.24 0.98 2.59Download WYNPSIVVHPHWREFDQVPAVYYSLGIFIGICGIIGCGGNGIVIYLFTKTKSLQTPANMFIINLAFSDFTFSLVNGPLMTISCFLKKWIFGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAASKKMSHRRAFIMIIFVWLWSVLWAIGPIFGTLEGVLC-----NCSFDYITRSNILCMFILGFFGPILIIFFCYFNIVMSVSNHEKEMAAMAK-RLNAKERLAKISIVIVSQFLLSWSPYAVVALLAQFGPLVTPYAAQLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVLTCCQF
95tgzA 0.21 0.25 0.89 4.78Download GENFMDIECFMVL----NPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCPSYHFIGSLAVADLLGSVIFVYSFIDFHVFH-RKDSRNVFLFKLGGVTASFTASVGSLFLAAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLG---------NCEK---------LQSVCSDIFHIDKTYLMFWIGVVSVLLLFIVYAYMYILWKAHSHAPDQARELAKTLVLILVVLIICWGPLLAIMVYDVFGKMN-FAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMF---------
102ydoA 0.14 0.18 0.93 5.57Download ---------------------SSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSAAAADILVGVLAIPFAIA--ISTGFCAACHGCLFIACFVLVLTASSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKAHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRFLAARRQLKQMESTLQKEVHAAKSLAIIVGLFALCCFTFFCPDCSHAPLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQE
(a)All the residues are colored in black; however, those residues in template which are identical to the residue in the query sequence are highlighted in color. Coloring scheme is based on the property of amino acids, where polar are brightly coloured while non-polar residues are colored in dark shade. (more about the colors used)
(b)Rank of templates represents the top ten threading templates used by GPCR-I-TASSER.
(c)Ident1 is the percentage sequence identity of the templates in the threading aligned region with the query sequence.
(d)Ident2 is the percentage sequence identity of the whole template chains with query sequence.
(e)Cov. represents the coverage of the threading alignment and is equal to the number of aligned residues divided by the length of query protein.
(f)Norm. Z-score is the normalized Z-score of the threading alignments. Alignment with a Normalized Z-score >1 mean a good alignment and vice versa.
(g)Download Align. provides the 3D structure of the aligned regions of the threading templates.
(h)The top 10 alignments reported above (in order of their ranking) are from the following threading programs:
       1: MUSTER   2: FFAS-3D   3: SPARKS-X   4: HHSEARCH2   5: HHSEARCH I   6: Neff-PPAS   7: HHSEARCH   8: pGenTHREADER   9: wdPPAS   10: cdPPAS   

  Top 5 Models Predicted by GPCR-I-TASSER

Generated 3D models Estimated local accuracy of models
  • Download Model 1
  • C-score=-0.31 (Read more about C-score)
  • Estimated TM-score = 0.67±0.13
  • Estimated RMSD = 6.9±4.1Å

  • Download Model 2
  • C-score = -0.98

  • Download Model 3
  • C-score = -2.29

  • Download Model 4
  • C-score = -2.39

  • Download Model 5
  • C-score = -2.97


    • [Click on A6NHA9_results.tar.bz2 to download the tarball file including all modeling results listed on this page]