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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL606788
Molecular formula	C17H21N5
IUPAC name	6-[3-(methylamino)azetidin-1-yl]-3,5-diazatricyclo[9.4.0.02,7]pentadeca-1(15),2(7),3,5,11,13-hexaen-4-amine
Molecular weight	295.39
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	2.2
Synonyms	6-[3-(methylamino)azetidin-1-yl]-3,5-diazatricyclo[9.4.0.0^{2,7}]pentadeca-1(15),2(7),3,5,11,13-hexaen-4-amine CHEMBL522673 2,4-diamino-5,6-disubstituted pyrimidine, 12 BDBM26398
Inchi Key	ZXPVZPKWXXNARI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H21N5/c1-19-12-9-22(10-12)16-14-8-4-6-11-5-2-3-7-13(11)15(14)20-17(18)21-16/h2-3,5,7,12,19H,4,6,8-10H2,1H3,(H2,18,20,21)
PubChem CID	25101945
ChEMBL	CHEMBL522673
IUPHAR	N/A
BindingDB	26398
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
439998	Histamine H4 receptor	Q91ZY1	Hrh4	Rattus norvegicus (Rat)	391
439999	Histamine H4 receptor	Q9H3N8	HRH4	Homo sapiens (Human)	390
440000	Histamine H4 receptor	Q91ZY2	Hrh4	Mus musculus (Mouse)	391

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