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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL603142
Molecular formula	C18H23N5
IUPAC name	6-[(3R)-3-(methylamino)pyrrolidin-1-yl]-3,5-diazatricyclo[9.4.0.02,7]pentadeca-1(15),2(7),3,5,11,13-hexaen-4-amine
Molecular weight	309.417
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	2.6
Synonyms	6-[(3R)-3-(methylamino)pyrrolidin-1-yl]-3,5-diazatricyclo[9.4.0.0^{2,7}]pentadeca-1(15),2(7),3,5,11,13-hexaen-4-amine CHEMBL521996 2,4-diamino-5,6-disubstituted pyrimidine, 11 BDBM26397
Inchi Key	ZNRXWEGEMFPRJE-CYBMUJFWSA-N
Inchi ID	InChI=1S/C18H23N5/c1-20-13-9-10-23(11-13)17-15-8-4-6-12-5-2-3-7-14(12)16(15)21-18(19)22-17/h2-3,5,7,13,20H,4,6,8-11H2,1H3,(H2,19,21,22)/t13-/m1/s1
PubChem CID	25071004
ChEMBL	CHEMBL521996
IUPHAR	N/A
BindingDB	26397
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
433075	Histamine H4 receptor	Q91ZY2	Hrh4	Mus musculus (Mouse)	391
433076	Histamine H4 receptor	Q91ZY1	Hrh4	Rattus norvegicus (Rat)	391
433077	Histamine H4 receptor	Q9H3N8	HRH4	Homo sapiens (Human)	390

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