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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3628734
Molecular formula	C24H33BrN4O
IUPAC name	4-(2-bromo-4-tert-butylphenyl)-8-[butyl(ethyl)amino]-6-methyl-1,3-dihydropyrido[2,3-b]pyrazin-2-one
Molecular weight	473.459
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	6.4
Synonyms	BDBM50128778
Inchi Key	MJSWCHNBFDPOGD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H33BrN4O/c1-7-9-12-28(8-2)20-13-16(3)26-23-22(20)27-21(30)15-29(23)19-11-10-17(14-18(19)25)24(4,5)6/h10-11,13-14H,7-9,12,15H2,1-6H3,(H,27,30)
PubChem CID	122193717
ChEMBL	CHEMBL3628734
IUPHAR	N/A
BindingDB	50128778
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
488593	Corticotropin-releasing factor receptor 1	P34998	CRHR1	Homo sapiens (Human)	444
488594	Corticotropin-releasing factor receptor 2	Q13324	CRHR2	Homo sapiens (Human)	411

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