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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	UNII-8U5620H545
Molecular formula	C17H21N5
IUPAC name	6-piperazin-1-yl-3,5-diazatricyclo[9.4.0.02,7]pentadeca-1(15),2(7),3,5,11,13-hexaen-4-amine
Molecular weight	295.39
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	2.2
Synonyms	8U5620H545 1027330-82-0 5H-Benzo(6,7)cyclohepta(1,2-d)pyrimidin-2-amine, 6,7-dihydro-4-(1-piperazinyl)- A-940894 2,4-diamino-5,6-disubstituted pyrimidine, 9 CHEMBL509540 6-(piperazin-1-yl)-3,5-diazatricyclo[9.4.0.0^{2,7}]pentadeca-1(15),2(7),3,5,11,13-hexaen-4-amine (4-(Piperazin-1-yl)-6,7-dihydro-5H-benzo(6,7)cyclohepta(1,2-d)pyrimidin-2-yl)amine BDBM26395 SCHEMBL604606 [ Show all ]
Inchi Key	KUZRWWLVBUPCRK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H21N5/c18-17-20-15-13-6-2-1-4-12(13)5-3-7-14(15)16(21-17)22-10-8-19-9-11-22/h1-2,4,6,19H,3,5,7-11H2,(H2,18,20,21)
PubChem CID	25071319
ChEMBL	CHEMBL509540
IUPHAR	N/A
BindingDB	26395
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
178948	Histamine H4 receptor	Q9H3N8	HRH4	Homo sapiens (Human)	390
178949	Histamine H4 receptor	Q91ZY1	Hrh4	Rattus norvegicus (Rat)	391
178950	Histamine H4 receptor	Q91ZY2	Hrh4	Mus musculus (Mouse)	391

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