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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1773293
Molecular formula	C22H26N4O6S
IUPAC name	tert-butyl 4-[[3-(4-methylsulfonylphenyl)-[1,2]oxazolo[4,5-d]pyrimidin-7-yl]oxy]piperidine-1-carboxylate
Molecular weight	474.532
Hydrogen bond acceptor	9
Hydrogen bond donor	0
XlogP	2.7
Synonyms	4-[3-(4-Methanesulfonyl-phenyl)-isoxazolo[4,5-d]pyrimidin-7-yloxy]-piperidine-1-carboxylic acid tert-butyl ester compound 29a tert-butyl 4-[[3-(4-methylsulfonylphenyl)-[1,2]oxazolo[5,4-e]pyrimidin-7-yl]oxy]piperidine-1-carboxylate 832717-22-3 GTPL5741 143144-EP2292620A2 tert-Butyl 4-((3-(4-methylsulfonylphenyl)-(1,2)oxazolo(5,4-E)pyrimidin-7-yl)oxy)piperidine-1-carboxylate compound 29a [PMID: 21444206] UNII-8L3B1I6V2T 143144-EP2287165A2 8L3B1I6V2T JYRWUSXRTGACLY-UHFFFAOYSA-N 4-(3-(4-Methanesulfonyl-phenyl)-isoxazolo(4,5-d)pyrimidin-7-yloxy)-piperidine-1-carboxylic acid tert-butyl ester tert-butyl 4-(3-(4-(methylsulfonyl)phenyl)isoxazolo[4,5-d]pyrimidin-7-yloxy)piperidine-1-carboxylate D06ACR 143144-EP2287166A2 BDBM50343445 SCHEMBL386450 [ Show all ]
Inchi Key	JYRWUSXRTGACLY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H26N4O6S/c1-22(2,3)31-21(27)26-11-9-15(10-12-26)30-20-19-18(23-13-24-20)17(25-32-19)14-5-7-16(8-6-14)33(4,28)29/h5-8,13,15H,9-12H2,1-4H3
PubChem CID	11397354
ChEMBL	CHEMBL1773293
IUPHAR	5741
BindingDB	50343445
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
163313	Glucose-dependent insulinotropic receptor	Q7TQN8	Gpr119	Rattus norvegicus (Rat)	468
163314	Glucose-dependent insulinotropic receptor	Q8TDV5	GPR119	Homo sapiens (Human)	335

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