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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2376803
Molecular formula	C16H22N6
IUPAC name	7-cyclopentyl-4-[3-(methylamino)azetidin-1-yl]pyrido[3,2-d]pyrimidin-2-amine
Molecular weight	298.394
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	2.1
Synonyms	BDBM50433358 SCHEMBL14895435
Inchi Key	HTLDHQKBLGJBRF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H22N6/c1-18-12-8-22(9-12)15-14-13(20-16(17)21-15)6-11(7-19-14)10-4-2-3-5-10/h6-7,10,12,18H,2-5,8-9H2,1H3,(H2,17,20,21)
PubChem CID	71525681
ChEMBL	CHEMBL2376803
IUPHAR	N/A
BindingDB	50433358
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
123585	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487
123586	Histamine H2 receptor	P25021	HRH2	Homo sapiens (Human)	359
123588	Histamine H3 receptor	Q9Y5N1	HRH3	Homo sapiens (Human)	445
123584	Histamine H4 receptor	Q9H3N8	HRH4	Homo sapiens (Human)	390
123587	Histamine H4 receptor	Q91ZY1	Hrh4	Rattus norvegicus (Rat)	391
123589	Histamine H4 receptor	Q91ZY2	Hrh4	Mus musculus (Mouse)	391

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