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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL27835
Molecular formula	C27H37N3O2
IUPAC name	[4-[4-[3-[(3S)-3-(dimethylamino)pyrrolidin-1-yl]propoxy]phenyl]phenyl]-(2-methylpyrrolidin-1-yl)methanone
Molecular weight	435.612
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	4.5
Synonyms	BDBM50222961
Inchi Key	AZDCRZSQRSOKCG-QBGQUKIHSA-N
Inchi ID	InChI=1S/C27H37N3O2/c1-21-6-4-17-30(21)27(31)24-9-7-22(8-10-24)23-11-13-26(14-12-23)32-19-5-16-29-18-15-25(20-29)28(2)3/h7-14,21,25H,4-6,15-20H2,1-3H3/t21?,25-/m0/s1
PubChem CID	44275558
ChEMBL	CHEMBL27835
IUPHAR	N/A
BindingDB	50222961
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
18044	Histamine H3 receptor	Q9Y5N1	HRH3	Homo sapiens (Human)	445
18045	Histamine H3 receptor	Q9QYN8	Hrh3	Rattus norvegicus (Rat)	445

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