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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3942295
Molecular formula	C17H17FN6O2
IUPAC name	[3-(3-ethyl-1,2,4-oxadiazol-5-yl)-8-methyl-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-(4-fluorophenyl)methanone
Molecular weight	356.361
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	1.4
Synonyms	US9422299, 40 BDBM242774 SCHEMBL16115514
Inchi Key	AWKTWOOCLJMRQH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H17FN6O2/c1-3-13-19-16(26-22-13)15-21-20-14-10(2)23(8-9-24(14)15)17(25)11-4-6-12(18)7-5-11/h4-7,10H,3,8-9H2,1-2H3
PubChem CID	86272101
ChEMBL	CHEMBL3942295
IUPHAR	N/A
BindingDB	242774
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
536394	Neuromedin-K receptor	P29371	TACR3	Homo sapiens (Human)	465
536393	Substance-K receptor	P21452	TACR2	Homo sapiens (Human)	398
536392	Substance-P receptor	P25103	TACR1	Homo sapiens (Human)	407

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