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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL426607
Molecular formula	C21H24Cl2N4O
IUPAC name	3-(2,4-dichlorophenyl)-7-(dicyclopropylmethyl)-8-ethyl-1-methyl-2H-purin-6-one
Molecular weight	419.35
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	5.2
Synonyms	BDBM50152049 SCHEMBL6321506 3-(2,4-Dichloro-phenyl)-7-dicyclopropylmethyl-8-ethyl-1-methyl-1,2,3,7-tetrahydro-purin-6-one
Inchi Key	AUECLXXBKDPVTQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H24Cl2N4O/c1-3-17-24-20-19(27(17)18(12-4-5-12)13-6-7-13)21(28)25(2)11-26(20)16-9-8-14(22)10-15(16)23/h8-10,12-13,18H,3-7,11H2,1-2H3
PubChem CID	10112776
ChEMBL	CHEMBL426607
IUPHAR	N/A
BindingDB	50152049
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
14544	Corticotropin-releasing factor receptor 1	P35353	Crhr1	Rattus norvegicus (Rat)	415
14543	Corticotropin-releasing factor receptor 2	Q13324	CRHR2	Homo sapiens (Human)	411

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