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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL360492
Molecular formula	C11H13ClFN
IUPAC name	7-chloro-8-fluoro-5-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine
Molecular weight	213.68
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	2.8
Synonyms	AELPHXGUKIVCSY-UHFFFAOYSA-N 8-Chloro-7-fluoro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine BDBM50161633 (1R,S)-8-chloro-7-fluoro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine SCHEMBL1094681 8-Chloro-7-fluoro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine [ Show all ]
Inchi Key	AELPHXGUKIVCSY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C11H13ClFN/c1-7-6-14-3-2-8-4-11(13)10(12)5-9(7)8/h4-5,7,14H,2-3,6H2,1H3
PubChem CID	9990808
ChEMBL	CHEMBL360492
IUPHAR	N/A
BindingDB	50161633
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
3617	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
3618	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
3616	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458

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