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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	AC1OJ1IV
Molecular formula	C19H23N5
IUPAC name	5-methyl-3-(prop-2-enylamino)-6-[(2,4,6-trimethylanilino)methyl]pyrazine-2-carbonitrile
Molecular weight	321.428
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	4.4
Synonyms	HMS2836O08 3-(allylamino)-6-[(mesitylamino)methyl]-5-methyl-2-pyrazinecarbonitrile SMR000477880 MLS001178355 5-methyl-3-(prop-2-enylamino)-6-[(2,4,6-trimethylanilino)methyl]pyrazine-2-carbonitrile ZINC4661759 CHEMBL1587946 3-(Allylamino)-5-methyl-6-[[(2,4,6-trimethylphenyl)amino]methyl]-2-pyrazinecarbonitrile MolPort-003-823-555 [ Show all ]
Inchi Key	AANRDBZIXJEKER-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H23N5/c1-6-7-21-19-16(10-20)24-17(15(5)23-19)11-22-18-13(3)8-12(2)9-14(18)4/h6,8-9,22H,1,7,11H2,2-5H3,(H,21,23)
PubChem CID	7312626
ChEMBL	CHEMBL1587946
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
362	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463

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