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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	4-ethyl-N-[3-(trifluoromethyl)phenyl]piperazine-1-carbothioamide
Molecular formula	C14H18F3N3S
IUPAC name	4-ethyl-N-[3-(trifluoromethyl)phenyl]piperazine-1-carbothioamide
Molecular weight	317.374
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	2.8
Synonyms	HMS2509G07 ZINC8829857 MolPort-002-242-909 SR-01000254669-1 MCULE-5769431005 AC1LI0KZ SMR000197584 CHEMBL1599743 STK029290 4-ethyl-N-[3-(trifluoromethyl)phenyl]-1-piperazinecarbothioamide MLS000577874 AKOS000962637 SR-01000254669 [ Show all ]
Inchi Key	AAJJLMKTUZDHEC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H18F3N3S/c1-2-19-6-8-20(9-7-19)13(21)18-12-5-3-4-11(10-12)14(15,16)17/h3-5,10H,2,6-9H2,1H3,(H,18,21)
PubChem CID	895910
ChEMBL	CHEMBL1599743
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
253	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463

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