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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Cannabinoid receptor 2
Species	Rattus norvegicus (Rat)
Gene	Cnr2
Synonym	Peripheral cannabinoid receptor CB2-R CB2 receptor CB2 CB-2 cannabinoid receptor 2 (spleen) cannabinoid receptor 2 (macrophage) rCB2 [ Show all ]
Disease	N/A for non-human GPCRs
Length	360
Amino acid sequence	MAGCRELELTNGSNGGLEFNPMKEYMILSDAQQIAVAVLCTLMGLLSALENVAVLYLILSSQRLRRKPSYLFIGSLAGADFLASVIFACNFVIFHVFHGVDSRNIFLLKIGSVTMTFTASVGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALGVMWVLSALISYLPLMGWTCCPSPCSELFPLIPNDYLLGWLLFIAILFSGIIYTYGYVLWKAHQHVASLAEHQDRQVPGIARMRLDVRLAKTLGLVMAVLLICWFPALALMGHSLVTTLSDKVKEAFAFCSMLCLVNSMINPIIYALRSGEIRSAAQHCLTGWKKYLQGLGSEGKEEAPKSSVTETEAEVKTTTGPGSRTPGCSNC
UniProt	Q9QZN9
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2470
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	arachidonylcyclopropylamide
Molecular formula	C23H37NO
IUPAC name	(5Z,8Z,11Z,14Z)-N-cyclopropylicosa-5,8,11,14-tetraenamide
Molecular weight	343.555
Hydrogen bond acceptor	1
Hydrogen bond donor	1
XlogP	6.6
Synonyms	1598AH AKOS024456525 BN0561 MolPort-003-940-098 arachidonoylcyclopropylamine CHEMBL418353 SCHEMBL6517985 (5Z,8Z,11Z,14Z)-N-Cyclopropyl-5,8,11,14-eicosatetraenamide acpa HMS3649N09 ZINC13674228 229021-64-1 Arachidonoyl Cyclopropylamide C23H37NO N-(Cyclopropyl)-5Z,8Z,11Z,14Z-eicosatetraenamide AC1NSJTH arachidonyl cyclopropylamide D02HDI SR-01000946681 (5Z,8Z,11Z,14Z)-N-cyclopropylicosa-5,8,11,14-tetraenamide ACPA (in Tocrisolvetrade mark 100) BDBM50006255 LS-63779 Arachidonoylcyclo-propylamide NCGC00162405-01 ACM229021641 Arachidonyl-cyclopropylamide GTPL739 SR-01000946681-1 [ Show all ]
Inchi Key	GLGAUBPACOBAMV-DOFZRALJSA-N
Inchi ID	InChI=1S/C23H37NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23(25)24-22-20-21-22/h6-7,9-10,12-13,15-16,22H,2-5,8,11,14,17-21H2,1H3,(H,24,25)/b7-6-,10-9-,13-12-,16-15-
PubChem CID	5311007
ChEMBL	CHEMBL418353
IUPHAR	739
BindingDB	50006255
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Ki	715.0 nM	PMID23865723	BindingDB,ChEMBL

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