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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Glucose-dependent insulinotropic receptor
Species	Mus musculus (Mouse)
Gene	Gpr119
Synonym	G protein-coupled receptor 119 G-protein coupled receptor 119 G-protein coupled receptor 2 glucose-dependent insulinotropic receptor GPCR2 GPR119 [ Show all ]
Disease	N/A for non-human GPCRs
Length	335
Amino acid sequence	MESSFSFGVILAVLTILIIAVNALVVVAMLLSIYKNDGVGLCFTLNLAVADTLIGVAISGLVTDQLSSSAQHTQKTLCSLRMAFVTSSAAASVLTVMLIAFDRYLAIKQPLRYFQIMNGLVAGACIAGLWLVSYLIGFLPLGVSIFQQTTYHGPCSFFAVFHPRFVLTLSCAGFFPAVLLFVFFYCDMLKIASVHSQQIRKMEHAGAMAGAYRPPRSVNDFKAVRTIAVLIGSFTLSWSPFLITSIVQVACHKCCLYQVLEKYLWLLGVGNSLLNPLIYAYWQREVRQQLYHMALGVKKFFTSILLLLPARNRGPERTRESAYHIVTISHPELDG
UniProt	Q7TQP3
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5263
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	SCHEMBL1447845
Molecular formula	C21H21F3N6O4
IUPAC name	[3-(trifluoromethyl)oxetan-3-yl] (3R)-4-[5-[(3-cyanopyridin-4-yl)methoxy]pyrimidin-2-yl]-3-methylpiperazine-1-carboxylate
Molecular weight	478.432
Hydrogen bond acceptor	12
Hydrogen bond donor	0
XlogP	1.5
Synonyms	CHEMBL3220237 4-[5-(3-Cyanopyridine-4-ylmethoxy)pyrimidine-2-yl]-5alpha-methylpiperazine-1-carboxylic acid 3-(trifluoromethyl)oxetane-3-yl ester
Inchi Key	GFSWORTTYOAWML-CQSZACIVSA-N
Inchi ID	InChI=1S/C21H21F3N6O4/c1-14-10-29(19(31)34-20(12-32-13-20)21(22,23)24)4-5-30(14)18-27-8-17(9-28-18)33-11-15-2-3-26-7-16(15)6-25/h2-3,7-9,14H,4-5,10-13H2,1H3/t14-/m1/s1
PubChem CID	58190317
ChEMBL	CHEMBL3220237
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor.

Experimental Data

Parameter	Value	Reference	Database source
EC50	158.49 nM	MedChemComm, (2013) 4:1:95	ChEMBL
Intrinsic activity	76.0 %	MedChemComm, (2013) 4:1:95	ChEMBL

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