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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
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GPCR

Name	G-protein coupled receptor 35
Species	Homo sapiens (Human)
Gene	GPR35
Synonym	G-protein coupled receptor 3 GPR35 KYNA receptor Kynurenic acid receptor
Disease	N/A
Length	309
Amino acid sequence	MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
UniProt	Q9HC97
Protein Data Bank	N/A
GPCR-HGmod model	Q9HC97
3D structure model	This predicted structure model is from GPCR-EXP Q9HC97.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1293267
IUPHAR	102
DrugBank	BE0005562

Ligand

Name	CHEMBL1914581
Molecular formula	C20H19N3O
IUPAC name	2-[5-(4-butylphenyl)-3-cyano-4,5-dimethylfuran-2-ylidene]propanedinitrile
Molecular weight	317.392
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	3.6
Synonyms	BDBM50357198 SCHEMBL405658 [3-Cyano-4,5-dimethyl-5-(4-butylphenyl)-2,5-dihydrofuran-2-ylidene]malononitrile
Inchi Key	FOFCIIMDQXFVOK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H19N3O/c1-4-5-6-15-7-9-17(10-8-15)20(3)14(2)18(13-23)19(24-20)16(11-21)12-22/h7-10H,4-6H2,1-3H3
PubChem CID	12138434
ChEMBL	CHEMBL1914581
IUPHAR	N/A
BindingDB	50357198
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Activity	100.0 %	PMID21950657	ChEMBL
EC50	15300.0 nM	PMID21950657	BindingDB,ChEMBL
IC50	6400.0 nM	PMID21950657	BindingDB,ChEMBL

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